iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037128

Ensembl Protein ID

ENSFALP00000005582.1

UniProt Accession

U3JS28; U3JS28_FICAL

Genbank Protein ID

ENSFALP00000005582

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001183

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005360.1	ENSFALT00000005609.1	ENSFALP00000005582.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	7.60e-08	32.0	5	45
ULD/UDP/UFD/UBX	1.20e-19	70.3	570	647
ULD/UDP/UBQ/UBQ_Other	4.10e-08	32.7	112	171

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 1    sededkleqlve.MGF.dreealqaLraannnleaAveyLl 39
           +++e++l+ +++ +G+ + +ea++ L+++n++l aA++ ++
   Q: 5    MDREMILADFQAcTGIeNIDEAITLLEQNNWDLVAAINGVI 45
           689**********************************9875 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           t++ ++l+iR+p+G++++r+F +s +l+ +++fv+ ++++++++++L+ +fPrr++++ + +++l e +L+p+++l++e
   Q: 570  TESVSKLRIRTPSGEFFERRFLASSKLQVVFDFVA-SKGYPWEEYKLLGTFPRRDVTQLDPNKSLLEVKLYPQETLFLE 647
           4559*******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+++K  +e +l ip   +++++kG      +d   L++++l+ ++ +++l
   Q: 112  NVDVVLEDSSTVGDIKHILENELQIP--ASKMLLKGWKTgdvDDSTVLKSLHLPKNNSLYVL 171
           4456667888****************..779**998887777***************99987 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MASNMDREMI LADFQACTGI ENIDEAITLL EQNNWDLVAA INGVIPQENG ILQSEYGVET 60
LHGPAYGPSS HSAAASSAPS SSSAFRHVVP SRQIVERQPR MLDFRVEYRD RNVDVVLEDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGGATGAT GGATGATGGA TGGATGGATG ATGGATGATG GATGGATGAT GGATGATGGA 60
TGGATGGATG ATGGATGATG GATGGATGAT GGATGATGCG GGACGCAGCT GGCTGCAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

KEGG

fab:101815138

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	91.09	0.00e+00	1151.00
IUUC-Apl-004127	Anas platyrhynchos	98.27	0.00e+00	1220.00
IUUC-Aca-005188	Anolis carolinensis	94.19	0.00e+00	1168.00
IUUC-Ame-010696	Astyanax mexicanus	76.26	0.00e+00	856.00
IUUC-Bta-012965	Bos taurus	91.09	0.00e+00	1153.00
IUUC-Cel-018420	Caenorhabditis elegans	28.24	2.00e-29	123.00
IUUC-Cja-019128	Callithrix jacchus	91.27	0.00e+00	1160.00
IUUC-Cfa-021201	Canis familiaris	73.15	0.00e+00	888.00
IUUC-Cpo-021475	Cavia porcellus	91.89	0.00e+00	859.00
IUUC-Csa-024076	Chlorocebus sabaeus	91.55	0.00e+00	1159.00
IUUC-Cho-025067	Choloepus hoffmanni	78.49	0.00e+00	1013.00
IUUC-Cin-025663	Ciona intestinalis	44.07	4.00e-70	258.00
IUUC-Csv-025894	Ciona savignyi	34.36	3.00e-71	262.00
IUUC-Dre-027508	Danio rerio	75.26	0.00e+00	948.00
IUUC-Dno-029336	Dasypus novemcinctus	90.63	0.00e+00	1142.00
IUUC-Dor-030218	Dipodomys ordii	84.18	0.00e+00	1037.00
IUUC-Dme-031581	Drosophila melanogaster	32.44	2.00e-93	336.00
IUUC-Ete-032860	Echinops telfairi	71.90	0.00e+00	635.00
IUUC-Eca-034321	Equus caballus	92.18	0.00e+00	994.00
IUUC-Eeu-034844	Erinaceus europaeus	69.09	9.00e-133	467.00
IUUC-Fca-036575	Felis catus	92.55	0.00e+00	689.00
IUUC-Gmo-038694	Gadus morhua	74.27	0.00e+00	912.00
IUUC-Gga-040826	Gallus gallus	98.31	0.00e+00	1253.00
IUUC-Gac-042125	Gasterosteus aculeatus	75.08	0.00e+00	977.00
IUUC-Ggo-045254	Gorilla gorilla	91.71	0.00e+00	1160.00
IUUC-Hsa-046722	Homo sapiens	91.55	0.00e+00	1160.00
IUUC-Hvu-047478	Hordeum vulgare	38.64	2.00e-07	50.40
IUUC-Itr-048149	Ictidomys tridecemlineatus	92.53	3.00e-97	346.00
IUUC-Lch-050312	Latimeria chalumnae	82.73	0.00e+00	691.00
IUUC-Loc-051990	Lepisosteus oculatus	81.40	0.00e+00	977.00
IUUC-Laf-054375	Loxodonta africana	93.10	0.00e+00	695.00
IUUC-Mcc-054627	Macaca mulatta	91.38	0.00e+00	1130.00
IUUC-Meu-056611	Macropus eugenii	69.77	8.00e-127	447.00
IUUC-Mga-059400	Meleagris gallopavo	96.15	0.00e+00	1228.00
IUUC-Mvi-060222	Microbotryum violaceum	34.21	7.30e-02	28.10
IUUC-Mmr-060882	Microcebus murinus	90.48	0.00e+00	1122.00
IUUC-Mdo-061874	Monodelphis domestica	90.92	0.00e+00	1181.00
IUUC-Mmu-063444	Mus musculus	90.17	0.00e+00	1145.00
IUUC-Mpu-065713	Mustela putorius furo	90.88	0.00e+00	1117.00
IUUC-Mlu-068122	Myotis lucifugus	88.96	0.00e+00	1095.00
IUUC-Nle-069025	Nomascus leucogenys	91.09	0.00e+00	1147.00
IUUC-Opr-071089	Ochotona princeps	80.49	0.00e+00	1038.00
IUUC-Ont-072421	Oreochromis niloticus	75.30	0.00e+00	964.00
IUUC-Oan-073092	Ornithorhynchus anatinus	88.68	0.00e+00	865.00
IUUC-Ola-086497	Oryzias latipes	75.41	0.00e+00	966.00
IUUC-Oga-088854	Otolemur garnettii	90.48	0.00e+00	1160.00
IUUC-Oar-090120	Ovis aries	90.94	0.00e+00	1129.00
IUUC-Ptr-091554	Pan troglodytes	91.71	0.00e+00	1160.00
IUUC-Pan-091985	Papio anubis	91.55	0.00e+00	1135.00
IUUC-Psi-093548	Pelodiscus sinensis	95.91	0.00e+00	1159.00
IUUC-Pma-094123	Petromyzon marinus	52.74	1.00e-53	202.00
IUUC-Pfo-096729	Poecilia formosa	74.33	0.00e+00	962.00
IUUC-Pab-097810	Pongo abelii	91.71	0.00e+00	1160.00
IUUC-Pca-101079	Procavia capensis	83.68	0.00e+00	849.00
IUUC-Pva-102534	Pteropus vampyrus	83.70	0.00e+00	875.00
IUUC-Rno-105127	Rattus norvegicus	88.94	0.00e+00	1036.00
IUUC-Sce-106395	Saccharomyces cerevisiae	23.37	5.00e-04	39.30
IUUC-Sha-106667	Sarcophilus harrisii	93.09	0.00e+00	1045.00
IUUC-Sar-113424	Sorex araneus	78.19	0.00e+00	628.00
IUUC-Ssc-115974	Sus scrofa	91.04	0.00e+00	1105.00
IUUC-Tgu-116495	Taeniopygia guttata	99.69	0.00e+00	1265.00
IUUC-Tru-118727	Takifugu rubripes	73.35	0.00e+00	944.00
IUUC-Tsy-118906	Tarsius syrichta	86.18	0.00e+00	1042.00
IUUC-Tni-119717	Tetraodon nigroviridis	76.69	0.00e+00	957.00
IUUC-Tbe-127849	Tupaia belangeri	78.04	0.00e+00	677.00
IUUC-Ttr-128660	Tursiops truncatus	87.12	0.00e+00	1087.00
IUUC-Vpa-130359	Vicugna pacos	90.88	0.00e+00	1123.00
IUUC-Xtr-132212	Xenopus tropicalis	87.79	0.00e+00	733.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence