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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045932
Ensembl Protein ID ENSP00000368813.2
UniProt Accession Q8N239; KLH34_HUMAN
Genbank Protein ID BAC03848.1; AAI09032.1
Protein Name Kelch-like protein 34
Genbank Nucleotide ID AK092279; AL772392
Gene Name KLHL34
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000185915.5 ENST00000379499.3 ENSP00000368813.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
miRTarBasemicroRNATRANSFACTargetScan
RepTarmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 4.50e-13 51.0 29 93
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +Dv+l+ +g+ef+ah++ La sS++F+alf+++  es+    ++++  ++  ++ ll+F+Yt  l+
   Q: 29   CDVTLETEGSEFPAHRSLLACSSDYFRALFKSHTQESR-ARVIHLHVPSAAGLQRLLDFIYTAWLS 93
           9************************************9.9******99**************8766 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MSYFLSYCKA HGGALLTGYQ ALRAEGFLCD VTLETEGSEF PAHRSLLACS SDYFRALFKS 60
HTQESRARVI HLHVPSAAGL QRLLDFIYTA WLSLSMDTVE DTLEAASYLQ VTEALGLCGR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045932|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTTGTCCCC GGCCTTCGCG GGTGCCCGCA GAACCCGTCC TCCTCGTCCA CCCCGGAGAG 60
GTCAGAGTCC TCGCCCTGCA CTCCCGGGAC GCCGCATCTG CGCCGTCGGA CATCCAGCAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045932|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005615--C:extracellular space
GO:0016567--P:protein ubiquitination
KEGG hsa:257240
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001332 Ailuropoda melanoleuca 85.12 0.00e+00 958.00
IUUC-Apl-003397 Anas platyrhynchos 52.58 1.00e-164 573.00
IUUC-Aca-005046 Anolis carolinensis 50.08 3.00e-161 561.00
IUUC-Ame-010614 Astyanax mexicanus 40.56 3.00e-116 412.00
IUUC-Bta-012398 Bos taurus 88.77 0.00e+00 916.00
IUUC-Cja-019513 Callithrix jacchus 87.75 0.00e+00 934.00
IUUC-Cfa-020271 Canis familiaris 87.96 0.00e+00 921.00
IUUC-Cpo-021570 Cavia porcellus 82.34 0.00e+00 954.00
IUUC-Csa-023939 Chlorocebus sabaeus 95.96 0.00e+00 1035.00
IUUC-Dre-027419 Danio rerio 38.57 7.00e-117 414.00
IUUC-Dno-029912 Dasypus novemcinctus 87.35 0.00e+00 999.00
IUUC-Dor-030827 Dipodomys ordii 81.50 0.00e+00 926.00
IUUC-Eeu-035056 Erinaceus europaeus 81.45 0.00e+00 905.00
IUUC-Fca-036382 Felis catus 78.63 0.00e+00 883.00
IUUC-Fal-037567 Ficedula albicollis 51.54 4.00e-169 588.00
IUUC-Gga-040307 Gallus gallus 52.86 2.00e-167 582.00
IUUC-Gac-041818 Gasterosteus aculeatus 37.22 1.00e-89 323.00
IUUC-Ggo-045460 Gorilla gorilla 93.16 0.00e+00 953.00
IUUC-Itr-048321 Ictidomys tridecemlineatus 83.03 0.00e+00 859.00
IUUC-Lch-050093 Latimeria chalumnae 44.80 1.00e-150 526.00
IUUC-Loc-052133 Lepisosteus oculatus 43.62 6.00e-127 447.00
IUUC-Laf-053511 Loxodonta africana 88.10 2.00e-135 475.00
IUUC-Mcc-055396 Macaca mulatta 95.96 0.00e+00 1008.00
IUUC-Mmr-060664 Microcebus murinus 89.64 0.00e+00 917.00
IUUC-Mdo-062058 Monodelphis domestica 72.27 0.00e+00 836.00
IUUC-Mmu-064318 Mus musculus 82.66 0.00e+00 884.00
IUUC-Mpu-065754 Mustela putorius furo 85.71 0.00e+00 956.00
IUUC-Opr-070464 Ochotona princeps 81.13 0.00e+00 699.00
IUUC-Ont-071463 Oreochromis niloticus 35.68 7.00e-92 331.00
IUUC-Ocu-074434 Oryctolagus cuniculus 84.22 0.00e+00 920.00
IUUC-Ola-086467 Oryzias latipes 37.24 6.00e-95 341.00
IUUC-Oga-089092 Otolemur garnettii 85.20 0.00e+00 894.00
IUUC-Ptr-090457 Pan troglodytes 91.93 0.00e+00 954.00
IUUC-Pan-092610 Papio anubis 95.96 0.00e+00 1016.00
IUUC-Psi-093009 Pelodiscus sinensis 49.44 9.00e-170 590.00
IUUC-Pfo-097358 Poecilia formosa 35.93 7.00e-91 328.00
IUUC-Pab-097741 Pongo abelii 96.96 0.00e+00 1008.00
IUUC-Pva-102251 Pteropus vampyrus 88.25 0.00e+00 976.00
IUUC-Rno-105869 Rattus norvegicus 82.92 0.00e+00 876.00
IUUC-Sha-107242 Sarcophilus harrisii 70.02 0.00e+00 777.00
IUUC-Tgu-116693 Taeniopygia guttata 50.97 1.00e-171 596.00
IUUC-Tru-117864 Takifugu rubripes 34.64 4.00e-85 309.00
IUUC-Tsy-118840 Tarsius syrichta 89.74 0.00e+00 1002.00
IUUC-Tbe-128143 Tupaia belangeri 86.99 4.00e-175 608.00
IUUC-Xtr-132958 Xenopus tropicalis 46.76 2.00e-155 542.00
Created Date 25-Jun-2017

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