iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.30e-09	37.2	104	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCl++f++  ++ +C H f++ C+q w      s++++ CPlC+
   Q: 104  CPICLDRFDNVSYLDRCLHKFCFRCVQEW------SKNKAECPLCK 143
           **********999999*************......**********7 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGSQPPPLGS PLSREEGEAP PLAPAEEGRR RSRRVRLRGS CRHRPSLLGR RELASSGPAV 60
PATASSEIMA SAAKEFKMDN FSPKAGTSKL QQTVPADASP DSKCPICLDR FDNVSYLDRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGATACAATT CTGGAGACTG GAGAAGTAAT TCCACCAATG AGAGATTTTC CTGATAAACA 60
TCATTGAAGA GCTCTTAAAA ATTTAAAAAA CTTGTGTAAC AGCACAAGTA TGTTTCAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0413--Isomerase
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005814--C:centriole
GO:0036064--C:ciliary basal body
GO:0000930--C:gamma-tubulin complex
GO:0016607--C:nuclear speck
GO:0032391--C:photoreceptor connecting cilium
GO:0016605--C:PML body
GO:0000922--C:spindle pole
GO:0000151--C:ubiquitin ligase complex
GO:0003823--F:antigen binding
GO:0003677--F:DNA binding
GO:0016853--F:isomerase activity
GO:0019789--F:SUMO transferase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0051457--P:maintenance of protein location in nucleus
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination
GO:0042127--P:regulation of cell proliferation

KEGG

rno:362501

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000940	Aegilops tauschii	36.76	2.00e-09	56.20
IUUC-Aml-002240	Ailuropoda melanoleuca	84.89	0.00e+00	848.00
IUUC-Atr-002964	Amborella trichopoda	35.42	2.00e-13	69.70
IUUC-Apl-003666	Anas platyrhynchos	56.73	1.00e-139	490.00
IUUC-Aca-005305	Anolis carolinensis	61.86	3.00e-144	506.00
IUUC-Aly-005926	Arabidopsis lyrata	36.17	2.00e-11	62.80
IUUC-Ath-007299	Arabidopsis thaliana	35.11	7.00e-12	64.30
IUUC-Ame-011109	Astyanax mexicanus	54.10	2.00e-111	397.00
IUUC-Bta-012637	Bos taurus	87.50	0.00e+00	876.00
IUUC-Bdi-014270	Brachypodium distachyon	40.00	2.00e-11	63.20
IUUC-Bol-015307	Brassica oleracea	32.98	3.00e-10	58.90
IUUC-Bra-017073	Brassica rapa	44.90	1.00e-08	52.80
IUUC-Cja-019105	Callithrix jacchus	88.81	0.00e+00	918.00
IUUC-Cfa-021203	Canis familiaris	85.42	0.00e+00	838.00
IUUC-Cpo-022335	Cavia porcellus	81.55	0.00e+00	801.00
IUUC-Csa-023870	Chlorocebus sabaeus	87.99	0.00e+00	905.00
IUUC-Cho-024870	Choloepus hoffmanni	85.37	0.00e+00	833.00
IUUC-Cne-026788	Cryptococcus neoformans	33.85	3.00e-07	50.80
IUUC-Dre-027535	Danio rerio	51.63	1.00e-123	437.00
IUUC-Dno-028963	Dasypus novemcinctus	85.08	0.00e+00	828.00
IUUC-Dor-030239	Dipodomys ordii	84.46	0.00e+00	741.00
IUUC-Dme-031941	Drosophila melanogaster	32.53	2.00e-38	155.00
IUUC-Ete-032300	Echinops telfairi	78.38	0.00e+00	1056.00
IUUC-Eca-033690	Equus caballus	87.05	0.00e+00	841.00
IUUC-Eeu-035257	Erinaceus europaeus	83.84	0.00e+00	816.00
IUUC-Fca-036383	Felis catus	84.72	0.00e+00	835.00
IUUC-Fal-037209	Ficedula albicollis	62.55	2.00e-157	549.00
IUUC-Gmo-039416	Gadus morhua	52.69	4.00e-117	414.00
IUUC-Gga-041267	Gallus gallus	68.96	2.00e-166	580.00
IUUC-Gac-042227	Gasterosteus aculeatus	49.26	3.00e-114	405.00
IUUC-Gma-042777	Glycine max	32.58	2.00e-09	56.20
IUUC-Ggo-044445	Gorilla gorilla	89.34	0.00e+00	925.00
IUUC-Hsa-045844	Homo sapiens	89.51	0.00e+00	927.00
IUUC-Hvu-047531	Hordeum vulgare	46.00	1.00e-10	57.40
IUUC-Itr-048818	Ictidomys tridecemlineatus	87.12	0.00e+00	875.00
IUUC-Lch-050031	Latimeria chalumnae	63.29	5.00e-158	551.00
IUUC-Lpe-051274	Leersia perrieri	37.74	9.00e-09	53.90
IUUC-Loc-052944	Lepisosteus oculatus	58.20	9.00e-140	490.00
IUUC-Laf-053820	Loxodonta africana	87.52	0.00e+00	801.00
IUUC-Mcc-054800	Macaca mulatta	87.80	0.00e+00	898.00
IUUC-Meu-056806	Macropus eugenii	72.43	5.00e-176	610.00
IUUC-Mtr-058378	Medicago truncatula	34.58	7.00e-13	67.40
IUUC-Mla-059017	Melampsora laricipopulina	36.07	4.00e-09	55.50
IUUC-Mvi-060417	Microbotryum violaceum	26.22	2.00e-17	84.30
IUUC-Mmr-061481	Microcebus murinus	87.39	0.00e+00	858.00
IUUC-Mdo-062219	Monodelphis domestica	79.44	5.00e-99	355.00
IUUC-Mmu-064138	Mus musculus	95.67	0.00e+00	919.00
IUUC-Mlu-067088	Myotis lucifugus	85.62	0.00e+00	872.00
IUUC-Nle-069862	Nomascus leucogenys	88.15	0.00e+00	940.00
IUUC-Opr-071076	Ochotona princeps	87.26	0.00e+00	753.00
IUUC-Ont-072225	Oreochromis niloticus	47.65	3.00e-110	393.00
IUUC-Oan-073069	Ornithorhynchus anatinus	65.07	8.00e-153	533.00
IUUC-Ocu-074826	Oryctolagus cuniculus	88.29	0.00e+00	881.00
IUUC-Oba-075429	Oryza barthii	37.68	1.00e-10	60.50
IUUC-Obr-076084	Oryza brachyantha	36.23	4.00e-10	58.50
IUUC-Ogl-077444	Oryza glaberrima	37.68	1.00e-10	60.10
IUUC-Ogu-078603	Oryza glumaepatula	37.68	1.00e-10	60.50
IUUC-Oin-079777	Oryza indica	37.68	1.00e-10	59.70
IUUC-Oni-082396	Oryza nivara	37.68	1.00e-10	60.50
IUUC-Opu-083698	Oryza punctata	36.62	7.00e-10	57.80
IUUC-Oru-084305	Oryza rufipogon	37.68	1.00e-10	60.50
IUUC-Ola-087377	Oryzias latipes	55.99	1.00e-107	383.00
IUUC-Oga-088059	Otolemur garnettii	83.88	0.00e+00	862.00
IUUC-Oar-089592	Ovis aries	88.00	0.00e+00	832.00
IUUC-Ptr-091233	Pan troglodytes	89.34	0.00e+00	925.00
IUUC-Pan-092743	Papio anubis	87.82	0.00e+00	901.00
IUUC-Psi-093669	Pelodiscus sinensis	59.42	0.00e+00	804.00
IUUC-Ppa-095668	Physcomitrella patens	25.95	5.00e-21	95.50
IUUC-Pfo-096706	Poecilia formosa	53.96	1.00e-105	377.00
IUUC-Pop-099119	Populus trichocarpa	24.10	6.00e-13	67.80
IUUC-Pca-100967	Procavia capensis	86.08	0.00e+00	756.00
IUUC-Ppe-101922	Prunus persica	27.27	4.00e-12	65.10
IUUC-Pva-102982	Pteropus vampyrus	86.97	0.00e+00	852.00
IUUC-Pgr-103551	Puccinia graminis	34.25	7.00e-09	54.30
IUUC-Ptt-103977	Puccinia triticina	33.33	4.00e-08	51.60
IUUC-Sha-106588	Sarcophilus harrisii	67.88	5.00e-173	602.00
IUUC-Sja-107735	Schizosaccharomyces japonicus	35.38	2.00e-07	49.30
IUUC-Smo-109039	Selaginella moellendorffii	25.69	2.00e-18	87.00
IUUC-Sly-111835	Solanum lycopersicum	42.37	1.00e-08	55.50
IUUC-Stu-112898	Solanum tuberosum	42.37	1.00e-08	55.50
IUUC-Sar-113622	Sorex araneus	84.81	3.00e-151	529.00
IUUC-Sre-115041	Sporisorium reilianum	38.36	1.00e-09	57.40
IUUC-Ssc-115244	Sus scrofa	87.12	0.00e+00	827.00
IUUC-Tgu-117180	Taeniopygia guttata	64.05	9.00e-166	577.00
IUUC-Tru-118393	Takifugu rubripes	54.04	5.00e-120	425.00
IUUC-Tsy-119408	Tarsius syrichta	89.00	0.00e+00	876.00
IUUC-Tni-120664	Tetraodon nigroviridis	55.08	9.00e-119	421.00
IUUC-Tca-121712	Theobroma cacao	26.81	1.00e-16	80.50
IUUC-Tae-122787	Triticum aestivum	38.57	1.00e-10	60.50
IUUC-Tbe-127301	Tupaia belangeri	78.98	0.00e+00	780.00
IUUC-Ttr-128204	Tursiops truncatus	86.82	0.00e+00	886.00
IUUC-Uma-129420	Ustilago maydis	43.06	8.00e-10	57.80
IUUC-Vpa-130297	Vicugna pacos	86.84	0.00e+00	831.00
IUUC-Vvi-131157	Vitis vinifera	25.73	2.00e-17	83.20
IUUC-Xtr-132845	Xenopus tropicalis	64.25	4.00e-164	572.00
IUUC-Xma-133439	Xiphophorus maculatus	53.70	1.00e-107	384.00
IUUC-Yli-134652	Yarrowia lipolytica	38.78	5.00e-06	46.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence