iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052409

Ensembl Protein ID

ENSLOCP00000020227.1

UniProt Accession

W5NHW8; W5NHW8_LEPOC

Genbank Protein ID

ENSLOCP00000020227

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01008641

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000016379.1	ENSLOCT00000020261.1	ENSLOCP00000020227.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.70e-55	180.8	142	178
UBD/Beta-Prp	2.60e-73	247.0	12	183

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +Ht++v+c +f +d +l+vs++dD ++++WD+++  +
   Q: 142  QHTNWVRCARFsPDgRLIVSCGDDRSVRLWDTTSRQC 178
           5***********999****************998776 PP

UBD/Beta-Prp

   S: 88   htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           +++kgh+d v++ +fsp+++ l++Gs+d  +++w+l+ +      + gh++vv++v+++p+g+l++sGs DrtvrlW  + +   + +t
   Q: 12   RHFKGHKDAVTCADFSPTNKQLATGSADTFLMIWNLKPKARAF-RFFGHKDVVSSVQFSPSGSLVASGSRDRTVRLWTPSIKGESTVFT 99
           7899999999999999999999999999999999999999888.899999999999999999999999999999999998888888888 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlq 261
             ht  v+s+sf+++g+ lv++s+d+++k+w++++++ + +ln ht++v++ rfsp++ ++vs+++D+s+r+Wd++s+++++t++
   Q: 100  A-HTATVRSVSFSQDGQKLVTASDDKSLKVWSVHRQRFLFSLNQHTNWVRCARFSPDGRLIVSCGDDRSVRLWDTTSRQCINTFT 183
           7.99999999999999999999999999999999999999999999999999999999999999999999999999999999986 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MASVLEDPTL ERHFKGHKDA VTCADFSPTN KQLATGSADT FLMIWNLKPK ARAFRFFGHK 60
DVVSSVQFSP SGSLVASGSR DRTVRLWTPS IKGESTVFTA HTATVRSVSF SQDGQKLVTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTAGATATG CACATTAAGT TTGCAAAGAT TCCTCGGTAC TCTGCTGCCA GGGTCTGTGT 60
CTCAAGCTGT AGGGTTTGAC ACAGAGGAAA AGGCTGGTAG AAACGATGGG GGATTTCCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0060271--P:cilium assembly
GO:0060287--P:epithelial cilium movement involved in determination of left/right asymmetry
GO:0007507--P:heart development
GO:0007634--P:optokinetic behavior
GO:0003014--P:renal system process
GO:0010842--P:retina layer formation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002219	Ailuropoda melanoleuca	56.50	1.00e-149	522.00
IUUC-Apl-004219	Anas platyrhynchos	61.14	1.00e-156	546.00
IUUC-Aca-005197	Anolis carolinensis	56.20	2.00e-158	552.00
IUUC-Ame-011000	Astyanax mexicanus	70.44	0.00e+00	693.00
IUUC-Bta-012706	Bos taurus	58.99	2.00e-165	575.00
IUUC-Cja-019185	Callithrix jacchus	57.05	1.00e-149	522.00
IUUC-Cfa-021274	Canis familiaris	59.06	3.00e-164	571.00
IUUC-Cpo-022351	Cavia porcellus	58.16	2.00e-162	565.00
IUUC-Csa-023032	Chlorocebus sabaeus	57.60	1.00e-159	555.00
IUUC-Cho-024508	Choloepus hoffmanni	51.57	1.00e-117	416.00
IUUC-Dre-028703	Danio rerio	68.45	0.00e+00	662.00
IUUC-Dno-028915	Dasypus novemcinctus	58.54	4.00e-153	534.00
IUUC-Ete-032353	Echinops telfairi	51.72	5.00e-133	467.00
IUUC-Eca-034136	Equus caballus	58.05	4.00e-151	527.00
IUUC-Eeu-034611	Erinaceus europaeus	52.63	6.00e-114	403.00
IUUC-Fca-036205	Felis catus	56.94	3.00e-147	514.00
IUUC-Fal-036947	Ficedula albicollis	52.56	2.00e-137	482.00
IUUC-Gga-040847	Gallus gallus	58.90	3.00e-157	548.00
IUUC-Ggo-045194	Gorilla gorilla	57.84	1.00e-163	568.00
IUUC-Hsa-047026	Homo sapiens	57.84	2.00e-163	568.00
IUUC-Lch-050067	Latimeria chalumnae	67.84	0.00e+00	679.00
IUUC-Laf-053428	Loxodonta africana	59.31	3.00e-162	564.00
IUUC-Mcc-054772	Macaca mulatta	58.69	3.00e-165	574.00
IUUC-Meu-056496	Macropus eugenii	59.45	8.00e-126	443.00
IUUC-Mga-059276	Meleagris gallopavo	57.17	7.00e-159	553.00
IUUC-Mmr-061525	Microcebus murinus	58.26	2.00e-162	565.00
IUUC-Mdo-062351	Monodelphis domestica	54.62	2.00e-156	545.00
IUUC-Mmu-063834	Mus musculus	58.14	1.00e-157	549.00
IUUC-Mpu-066453	Mustela putorius furo	58.90	7.00e-164	570.00
IUUC-Mlu-067909	Myotis lucifugus	57.66	5.00e-151	527.00
IUUC-Nle-069206	Nomascus leucogenys	58.05	4.00e-164	570.00
IUUC-Opr-070566	Ochotona princeps	51.06	4.00e-132	464.00
IUUC-Ont-072587	Oreochromis niloticus	73.64	3.00e-170	590.00
IUUC-Oan-073726	Ornithorhynchus anatinus	58.80	2.00e-150	525.00
IUUC-Ocu-074639	Oryctolagus cuniculus	58.99	9.00e-164	569.00
IUUC-Ola-086913	Oryzias latipes	63.12	7.00e-175	606.00
IUUC-Oga-088061	Otolemur garnettii	65.42	2.00e-142	498.00
IUUC-Oar-090228	Ovis aries	56.77	2.00e-166	578.00
IUUC-Ptr-091420	Pan troglodytes	58.05	4.00e-164	570.00
IUUC-Pan-092228	Papio anubis	58.47	6.00e-165	573.00
IUUC-Psi-093309	Pelodiscus sinensis	60.04	3.00e-161	561.00
IUUC-Pfo-096162	Poecilia formosa	67.56	6.00e-148	516.00
IUUC-Pab-098109	Pongo abelii	58.05	9.00e-164	569.00
IUUC-Pva-102712	Pteropus vampyrus	59.24	2.00e-165	575.00
IUUC-Rno-105260	Rattus norvegicus	57.51	2.00e-157	548.00
IUUC-Sar-113446	Sorex araneus	55.58	5.00e-149	520.00
IUUC-Ssc-115794	Sus scrofa	66.85	3.00e-151	527.00
IUUC-Tgu-116770	Taeniopygia guttata	51.17	8.00e-135	473.00
IUUC-Tru-117968	Takifugu rubripes	61.36	4.00e-170	590.00
IUUC-Tni-119953	Tetraodon nigroviridis	59.13	1.00e-157	549.00
IUUC-Tbe-128071	Tupaia belangeri	54.59	6.00e-135	473.00
IUUC-Ttr-129267	Tursiops truncatus	59.20	2.00e-164	572.00
IUUC-Vpa-130823	Vicugna pacos	58.61	6.00e-124	437.00
IUUC-Xtr-131768	Xenopus tropicalis	61.57	1.00e-174	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence