iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Opr-070301

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Recombination activating protein 1

Genbank Nucleotide ID

AY249881

Gene Name

RNF125; RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOPRG00000011476.1	ENSOPRT00000011477.1	ENSOPRP00000010471.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.00e-08	35.2	37	76
E3 activity/RING/U-box	1.20e-09	37.8	33	97

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CSVCLEVLHQ-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqaw 68
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++
   Q: 33   TSFDCSVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEY 97
           57*******************************99999*********999999999999999987 PP

Organism

Ochotona princeps

Protein Sequence
(Fasta)

MGSVLSSETG KSAPSSATPR ALERKGDPEL PLTSFDCSVC LEVLHQPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYQNC TECDTLXXXX XXXXXXXXXX 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCCG TGCTGAGCAG CGAAACTGGC AAGTCTGCTC CTTCCTCTGC CACCCCACGG 60
GCCCTGGAGC GCAAGGGGGA CCCGGAGCTG CCCCTCACTT CTTTCGACTG CTCCGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF00097--zf-C3HC4
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	80.17	5.00e-107	379.00
IUUC-Aca-004839	Anolis carolinensis	51.16	7.00e-49	186.00
IUUC-Bta-012827	Bos taurus	78.02	5.00e-105	373.00
IUUC-Bdi-014205	Brachypodium distachyon	43.08	1.00e-09	54.30
IUUC-Cja-018794	Callithrix jacchus	78.45	3.00e-104	370.00
IUUC-Cfa-021234	Canis familiaris	78.88	1.00e-97	348.00
IUUC-Cpo-022412	Cavia porcellus	68.10	2.00e-85	307.00
IUUC-Csa-023406	Chlorocebus sabaeus	79.74	3.00e-106	377.00
IUUC-Cho-024427	Choloepus hoffmanni	96.05	1.00e-75	275.00
IUUC-Dno-030085	Dasypus novemcinctus	78.45	1.00e-104	371.00
IUUC-Dor-030911	Dipodomys ordii	88.30	1.00e-33	135.00
IUUC-Ete-032469	Echinops telfairi	75.43	7.00e-100	355.00
IUUC-Eca-034352	Equus caballus	79.74	4.00e-106	376.00
IUUC-Eeu-034889	Erinaceus europaeus	65.09	6.00e-81	293.00
IUUC-Fca-036116	Felis catus	78.88	2.00e-99	354.00
IUUC-Hsa-046518	Homo sapiens	78.88	9.00e-105	372.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	80.23	1.00e-78	285.00
IUUC-Laf-053363	Loxodonta africana	80.34	1.00e-106	378.00
IUUC-Meu-056101	Macropus eugenii	65.88	1.00e-78	285.00
IUUC-Mdo-062046	Monodelphis domestica	63.09	2.00e-80	291.00
IUUC-Mmu-063184	Mus musculus	65.71	8.00e-38	148.00
IUUC-Mpu-065708	Mustela putorius furo	79.74	1.00e-105	375.00
IUUC-Mlu-067561	Myotis lucifugus	71.19	2.00e-70	257.00
IUUC-Nle-069665	Nomascus leucogenys	77.57	9.00e-95	338.00
IUUC-Ocu-074562	Oryctolagus cuniculus	97.87	2.00e-51	193.00
IUUC-Oga-088958	Otolemur garnettii	80.17	1.00e-106	378.00
IUUC-Oar-089541	Ovis aries	75.71	1.00e-75	274.00
IUUC-Ptr-090989	Pan troglodytes	79.31	8.00e-106	375.00
IUUC-Pan-092372	Papio anubis	78.88	2.00e-105	374.00
IUUC-Pab-098718	Pongo abelii	66.38	7.00e-82	295.00
IUUC-Pca-100453	Procavia capensis	79.31	9.00e-105	372.00
IUUC-Pva-102931	Pteropus vampyrus	80.17	2.00e-98	351.00
IUUC-Rno-105771	Rattus norvegicus	75.00	1.00e-79	288.00
IUUC-Sha-107557	Sarcophilus harrisii	63.52	2.00e-85	308.00
IUUC-Sar-113435	Sorex araneus	92.55	1.00e-48	184.00
IUUC-Ssc-116388	Sus scrofa	79.74	2.00e-106	377.00
IUUC-Tsy-119439	Tarsius syrichta	77.40	2.00e-76	277.00
IUUC-Tbe-127417	Tupaia belangeri	74.29	2.00e-37	148.00
IUUC-Ttr-129212	Tursiops truncatus	79.74	6.00e-107	379.00
IUUC-Vpa-130153	Vicugna pacos	78.45	4.00e-104	369.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence