iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033207

UUCD1 version

UUC-EqC-00239

Ensembl Protein ID

ENSECAP00000013378.1

UniProt Accession

F6TSM5; F6TSM5_HORSE

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015712.1	ENSECAT00000016565.1	ENSECAP00000013378.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-08	35.6	15	59
E3 activity/RING/U-box	7.00e-06	26.2	9	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iCle + + pl+l+CgH f++ C+ + +++   +  e rCP+C+
   Q: 15   CPICLELLTK-PLSLDCGHNFCQACITANKDSRIDQGAERRCPVCQ 59
           ********99.***************6667899999*********7 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk.......tcPvtrqplteedlvPnltlrrliq 66
           + ee  CpI lel + P  l +G+ + +++I    +++ +        cPv++ p ++ +l+Pn  + ++++
   Q: 9    IKEEVTCPICLELLTKPLSLDCGHNFCQACITA--NKDSRidqgaerRCPVCQIPYKPGNLKPNRPMANIVE 78
           57899**************************98..444445677779*****************98777665 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MASGILVGIK EEVTCPICLE LLTKPLSLDC GHNFCQACIT ANKDSRIDQG AERRCPVCQI 60
PYKPGNLKPN RPMANIVERL REVKLRPEEE QKRDLCVRHE EKLLLFCKED GKVICRLCER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG GAATCTTGGT GGGCATAAAG GAGGAGGTGA CCTGCCCCAT CTGCCTGGAG 60
CTCCTGACAA AACCCCTGAG CCTAGACTGT GGCCACAACT TCTGTCAAGC CTGCATCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR010908--Longin_dom
IPR003877--SPRY_dom
IPR032917--TRIM5
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006118	Arabidopsis lyrata	39.62	1.00e-07	50.40
IUUC-Cja-019944	Callithrix jacchus	61.70	3.00e-159	555.00
IUUC-Dor-030700	Dipodomys ordii	48.97	9.00e-128	450.00
IUUC-Eeu-034968	Erinaceus europaeus	53.59	5.00e-125	440.00
IUUC-Mlu-067695	Myotis lucifugus	61.05	2.00e-160	558.00
IUUC-Opr-071057	Ochotona princeps	53.56	6.00e-136	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence