iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089048

Ensembl Protein ID

ENSOGAP00000004237.2

UniProt Accession

H0WQK5; H0WQK5_OTOGA

Genbank Protein ID

ENSOGAP00000004237

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03180149

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000004738.2	ENSOGAT00000004742.2	ENSOGAP00000004237.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.00e-14	53.3	168	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+gk G fP+n+v++++
   Q: 168  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGKTGWFPSNYVREIK 222
           68999*********************7..999*******..8**************997 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MNPEERIVTW LISLGVLDSP KKTICDPEEF LKSSLKNGVV LCKLINRLVP GSVEKYCLEP 60
QTEAECTNNI NDFLKACATL QVEVFNPDDL YSGVNFSKVL STLLAVNKAT EGQAIATGSE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAGCGAAT CGTGACATGG CTTATATCTT TGGGAGTTTT AGATTCCCCC 60
AAAAAGACCA TCTGTGATCC GGAGGAGTTT TTGAAGTCCT CGCTGAAGAA TGGGGTAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001631	Ailuropoda melanoleuca	82.77	0.00e+00	1308.00
IUUC-Apl-003960	Anas platyrhynchos	69.22	0.00e+00	942.00
IUUC-Bta-013527	Bos taurus	87.50	0.00e+00	1183.00
IUUC-Cja-018935	Callithrix jacchus	87.78	0.00e+00	1207.00
IUUC-Cfa-021269	Canis familiaris	86.36	0.00e+00	1195.00
IUUC-Cpo-021620	Cavia porcellus	82.82	0.00e+00	1129.00
IUUC-Csa-023415	Chlorocebus sabaeus	87.78	0.00e+00	1207.00
IUUC-Dno-029201	Dasypus novemcinctus	85.67	0.00e+00	1173.00
IUUC-Dor-030868	Dipodomys ordii	70.31	0.00e+00	883.00
IUUC-Eca-033500	Equus caballus	87.78	0.00e+00	1185.00
IUUC-Eeu-035269	Erinaceus europaeus	80.68	9.00e-163	566.00
IUUC-Fca-035683	Felis catus	86.08	0.00e+00	1172.00
IUUC-Fal-037611	Ficedula albicollis	69.93	0.00e+00	942.00
IUUC-Gga-040940	Gallus gallus	68.23	0.00e+00	939.00
IUUC-Ggo-044755	Gorilla gorilla	88.49	0.00e+00	1216.00
IUUC-Hsa-046210	Homo sapiens	88.07	0.00e+00	1211.00
IUUC-Lch-049517	Latimeria chalumnae	65.02	0.00e+00	912.00
IUUC-Laf-054196	Loxodonta africana	88.04	0.00e+00	1176.00
IUUC-Mcc-055716	Macaca mulatta	87.78	0.00e+00	1207.00
IUUC-Meu-056285	Macropus eugenii	71.61	0.00e+00	668.00
IUUC-Mtr-058576	Medicago truncatula	46.15	2.00e-11	62.80
IUUC-Mga-060029	Meleagris gallopavo	69.50	0.00e+00	961.00
IUUC-Mmr-060803	Microcebus murinus	89.20	0.00e+00	1197.00
IUUC-Mdo-062654	Monodelphis domestica	74.08	0.00e+00	1018.00
IUUC-Mmu-063479	Mus musculus	84.59	0.00e+00	1137.00
IUUC-Mpu-066065	Mustela putorius furo	86.64	0.00e+00	1171.00
IUUC-Mlu-068222	Myotis lucifugus	88.65	0.00e+00	1193.00
IUUC-Nle-069379	Nomascus leucogenys	88.35	0.00e+00	1214.00
IUUC-Opr-070687	Ochotona princeps	72.61	0.00e+00	810.00
IUUC-Ont-072240	Oreochromis niloticus	56.62	0.00e+00	915.00
IUUC-Oan-073067	Ornithorhynchus anatinus	71.13	0.00e+00	1157.00
IUUC-Ocu-074852	Oryctolagus cuniculus	86.93	0.00e+00	1174.00
IUUC-Oar-089339	Ovis aries	87.50	0.00e+00	1179.00
IUUC-Pan-092666	Papio anubis	85.55	0.00e+00	1160.00
IUUC-Psi-093116	Pelodiscus sinensis	69.79	0.00e+00	963.00
IUUC-Pma-094701	Petromyzon marinus	53.72	2.00e-110	392.00
IUUC-Pab-098567	Pongo abelii	88.35	0.00e+00	1216.00
IUUC-Pca-100997	Procavia capensis	74.72	0.00e+00	948.00
IUUC-Pva-102500	Pteropus vampyrus	86.08	0.00e+00	1142.00
IUUC-Rno-104974	Rattus norvegicus	84.74	0.00e+00	1117.00
IUUC-Sar-113420	Sorex araneus	81.39	0.00e+00	1081.00
IUUC-Ssc-115679	Sus scrofa	87.26	0.00e+00	1043.00
IUUC-Tgu-117069	Taeniopygia guttata	70.07	0.00e+00	961.00
IUUC-Tru-118488	Takifugu rubripes	55.14	0.00e+00	834.00
IUUC-Tsy-119243	Tarsius syrichta	77.33	0.00e+00	763.00
IUUC-Tni-120584	Tetraodon nigroviridis	58.63	0.00e+00	809.00
IUUC-Tbe-127994	Tupaia belangeri	75.32	0.00e+00	979.00
IUUC-Ttr-128839	Tursiops truncatus	88.31	0.00e+00	1167.00
IUUC-Vpa-130144	Vicugna pacos	78.41	0.00e+00	1025.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence