iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053703

Ensembl Protein ID

ENSLAFP00000015714.4

UniProt Accession

G3TLF1; G3TLF1_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KMT2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000018741.4	ENSLAFT00000018743.4	ENSLAFP00000015714.4
ENSLAFG00000018741.4	ENSLAFT00000033676.1	ENSLAFP00000019738.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.50e-30	103.5	864	917

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 864  KFCHVCGRKGRGTKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 917
           58********************************.88888877777******876 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

LLGLRRGLRR LRRLWAGPRL QVPEEESSDG ESDVEEFQGF HSDEDVAPSS LRSALRSQRG 60
RAPRGRGRKH KTTPVLPARL ADVAPTPPKT PARKRGEEGT ERMVQALTEL LRRAQAPPVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCTGGGGC TCCGCCGGGG CCTGCGCCGG CTCCGCCGCC TGTGGGCCGG CCCGCGCCTT 60
CAGCGGGGCC GGGGCCGGGG CCGGGGCCGG GGCTGGGGCC CGAGCCGGGG CTGGGTGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	86.11	0.00e+00	2657.00
IUUC-Aca-004718	Anolis carolinensis	53.31	0.00e+00	1763.00
IUUC-Ame-010705	Astyanax mexicanus	45.97	0.00e+00	920.00
IUUC-Bta-013578	Bos taurus	85.21	0.00e+00	2543.00
IUUC-Bdi-014882	Brachypodium distachyon	33.33	5.00e-27	115.00
IUUC-Bra-017422	Brassica rapa	33.33	2.00e-27	117.00
IUUC-Cja-019138	Callithrix jacchus	85.02	0.00e+00	2625.00
IUUC-Cfa-020020	Canis familiaris	85.95	0.00e+00	2577.00
IUUC-Cpo-021552	Cavia porcellus	83.31	0.00e+00	2575.00
IUUC-Csa-024216	Chlorocebus sabaeus	93.19	0.00e+00	2172.00
IUUC-Dre-027700	Danio rerio	48.46	0.00e+00	739.00
IUUC-Dno-029583	Dasypus novemcinctus	85.33	0.00e+00	2669.00
IUUC-Dor-030903	Dipodomys ordii	89.98	0.00e+00	1935.00
IUUC-Eca-034026	Equus caballus	94.39	0.00e+00	1898.00
IUUC-Eeu-034687	Erinaceus europaeus	95.41	0.00e+00	1062.00
IUUC-Fca-036311	Felis catus	86.53	0.00e+00	2641.00
IUUC-Gmo-039265	Gadus morhua	46.04	0.00e+00	826.00
IUUC-Gac-041840	Gasterosteus aculeatus	46.29	0.00e+00	848.00
IUUC-Ggo-044791	Gorilla gorilla	91.81	0.00e+00	2064.00
IUUC-Hsa-046988	Homo sapiens	92.75	0.00e+00	2119.00
IUUC-Hvu-047762	Hordeum vulgare	36.57	5.00e-20	92.80
IUUC-Itr-048907	Ictidomys tridecemlineatus	93.47	0.00e+00	2232.00
IUUC-Lpe-051476	Leersia perrieri	31.51	8.00e-24	105.00
IUUC-Loc-052252	Lepisosteus oculatus	53.44	0.00e+00	777.00
IUUC-Mcc-054782	Macaca mulatta	91.86	0.00e+00	2155.00
IUUC-Meu-056046	Macropus eugenii	87.05	0.00e+00	1660.00
IUUC-Mmr-061316	Microcebus murinus	89.97	0.00e+00	2159.00
IUUC-Mdo-062648	Monodelphis domestica	77.67	0.00e+00	2372.00
IUUC-Mmu-063579	Mus musculus	83.26	0.00e+00	2668.00
IUUC-Mac-064935	Musa acuminata	31.91	7.00e-30	125.00
IUUC-Mpu-066710	Mustela putorius furo	86.01	0.00e+00	2604.00
IUUC-Mlu-067559	Myotis lucifugus	91.89	0.00e+00	2152.00
IUUC-Nle-070085	Nomascus leucogenys	92.79	0.00e+00	1952.00
IUUC-Opr-071148	Ochotona princeps	82.54	0.00e+00	2580.00
IUUC-Ont-071626	Oreochromis niloticus	44.65	0.00e+00	889.00
IUUC-Ocu-074475	Oryctolagus cuniculus	83.72	0.00e+00	2525.00
IUUC-Obr-076458	Oryza brachyantha	34.48	1.00e-27	118.00
IUUC-Ogl-077851	Oryza glaberrima	36.26	7.00e-28	119.00
IUUC-Ogu-078706	Oryza glumaepatula	36.26	6.00e-28	119.00
IUUC-Oin-079802	Oryza indica	30.95	1.00e-22	101.00
IUUC-Osa-085421	Oryza sativa	36.26	1.00e-27	118.00
IUUC-Ola-086609	Oryzias latipes	49.00	0.00e+00	758.00
IUUC-Oga-088140	Otolemur garnettii	84.51	0.00e+00	2617.00
IUUC-Oar-089447	Ovis aries	92.51	0.00e+00	1963.00
IUUC-Ptr-090902	Pan troglodytes	92.89	0.00e+00	2130.00
IUUC-Pan-091930	Papio anubis	93.19	0.00e+00	2167.00
IUUC-Ppa-095221	Physcomitrella patens	36.02	1.00e-30	128.00
IUUC-Pfo-096884	Poecilia formosa	45.48	0.00e+00	902.00
IUUC-Pab-098404	Pongo abelii	90.59	0.00e+00	1018.00
IUUC-Pop-099585	Populus trichocarpa	34.44	4.00e-26	113.00
IUUC-Pca-100949	Procavia capensis	90.41	0.00e+00	1140.00
IUUC-Ppe-101920	Prunus persica	32.54	1.00e-27	118.00
IUUC-Pva-102634	Pteropus vampyrus	84.89	0.00e+00	2638.00
IUUC-Rno-105870	Rattus norvegicus	82.71	0.00e+00	2679.00
IUUC-Sit-110552	Setaria italica	34.33	2.00e-28	120.00
IUUC-Sar-113289	Sorex araneus	87.79	0.00e+00	1713.00
IUUC-Ssc-115509	Sus scrofa	85.22	0.00e+00	2645.00
IUUC-Tru-118413	Takifugu rubripes	51.89	0.00e+00	780.00
IUUC-Tca-121624	Theobroma cacao	33.17	6.00e-28	119.00
IUUC-Tae-124647	Triticum aestivum	36.57	4.00e-20	92.80
IUUC-Tbe-127825	Tupaia belangeri	89.96	0.00e+00	1154.00
IUUC-Ttr-128754	Tursiops truncatus	93.91	0.00e+00	1176.00
IUUC-Xtr-132838	Xenopus tropicalis	50.14	0.00e+00	994.00
IUUC-Xma-133119	Xiphophorus maculatus	42.36	0.00e+00	968.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence