iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021333

Ensembl Protein ID

ENSCPOP00000021087.1

UniProt Accession

H0WDL4; H0WDL4_CAVPO

Genbank Protein ID

ENSCPOP00000021087

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02013683

Gene Name

IFT80

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000026743.1	ENSCPOT00000021092.1	ENSCPOP00000021087.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-14	53.4	235	263

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 235  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 263
           99*********9978888887.689*9999 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MRLKISLLKE PNFLNMASHQ ELVSCVGWTT AEELYSCSDD HQIVKWNLLA SETSQIVKLP 60
DDIYPIDLHW FPKSLGTKKQ TQAESFVLTS SDGKFHLISK LGRVEKSVEA HCGAVLAGRW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGACTGA AGATATCTCT TTTAAAAGAA CCAAAGCATA TCCTTTTAAT ATTTACAAAC 60
TATATTGTAA TCACCTGATG ATAGTATTAT TGAACAGTTT TTTTTCCAGT TTTTTAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	95.58	0.00e+00	886.00
IUUC-Apl-003721	Anas platyrhynchos	77.50	0.00e+00	1210.00
IUUC-Aca-004488	Anolis carolinensis	77.30	0.00e+00	1217.00
IUUC-Ame-011402	Astyanax mexicanus	79.11	0.00e+00	807.00
IUUC-Bta-013037	Bos taurus	76.15	0.00e+00	1125.00
IUUC-Cel-018360	Caenorhabditis elegans	37.64	4.00e-161	561.00
IUUC-Cja-019076	Callithrix jacchus	82.88	0.00e+00	1030.00
IUUC-Cfa-020999	Canis familiaris	85.98	0.00e+00	1326.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	43.61	2.00e-169	589.00
IUUC-Csa-023699	Chlorocebus sabaeus	86.35	0.00e+00	1325.00
IUUC-Cho-024904	Choloepus hoffmanni	85.71	0.00e+00	814.00
IUUC-Cin-025399	Ciona intestinalis	51.85	0.00e+00	830.00
IUUC-Csv-026186	Ciona savignyi	50.64	0.00e+00	792.00
IUUC-Dre-028276	Danio rerio	67.73	0.00e+00	1124.00
IUUC-Dno-029824	Dasypus novemcinctus	86.95	0.00e+00	1335.00
IUUC-Dor-031141	Dipodomys ordii	81.42	0.00e+00	1228.00
IUUC-Dme-031620	Drosophila melanogaster	32.10	4.00e-121	429.00
IUUC-Ete-033028	Echinops telfairi	59.21	0.00e+00	676.00
IUUC-Eca-033339	Equus caballus	84.87	0.00e+00	1294.00
IUUC-Eeu-034909	Erinaceus europaeus	79.40	0.00e+00	803.00
IUUC-Fca-035780	Felis catus	86.15	0.00e+00	1296.00
IUUC-Fal-037447	Ficedula albicollis	71.24	0.00e+00	1099.00
IUUC-Gmo-038657	Gadus morhua	54.59	0.00e+00	704.00
IUUC-Gga-040689	Gallus gallus	77.89	0.00e+00	1206.00
IUUC-Gac-041586	Gasterosteus aculeatus	65.57	0.00e+00	871.00
IUUC-Hsa-047005	Homo sapiens	85.97	0.00e+00	1338.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	84.24	0.00e+00	927.00
IUUC-Lch-050459	Latimeria chalumnae	74.09	0.00e+00	1169.00
IUUC-Loc-052774	Lepisosteus oculatus	70.99	0.00e+00	910.00
IUUC-Laf-053765	Loxodonta africana	85.27	0.00e+00	1281.00
IUUC-Mcc-055052	Macaca mulatta	86.35	0.00e+00	1325.00
IUUC-Meu-056368	Macropus eugenii	73.43	0.00e+00	647.00
IUUC-Mga-059488	Meleagris gallopavo	78.03	0.00e+00	1213.00
IUUC-Mmr-061527	Microcebus murinus	85.36	0.00e+00	1303.00
IUUC-Mdo-062850	Monodelphis domestica	83.39	0.00e+00	1026.00
IUUC-Mmu-063117	Mus musculus	85.22	0.00e+00	1299.00
IUUC-Mpu-066550	Mustela putorius furo	84.70	0.00e+00	1181.00
IUUC-Mlu-067772	Myotis lucifugus	81.66	0.00e+00	1212.00
IUUC-Nle-069215	Nomascus leucogenys	85.33	0.00e+00	1326.00
IUUC-Opr-070725	Ochotona princeps	65.16	0.00e+00	927.00
IUUC-Ont-072147	Oreochromis niloticus	67.51	0.00e+00	1108.00
IUUC-Oan-073176	Ornithorhynchus anatinus	86.99	8.00e-63	231.00
IUUC-Ocu-073896	Oryctolagus cuniculus	84.29	0.00e+00	1024.00
IUUC-Ola-086767	Oryzias latipes	60.68	0.00e+00	818.00
IUUC-Oga-088113	Otolemur garnettii	85.49	0.00e+00	1328.00
IUUC-Oar-089683	Ovis aries	81.23	0.00e+00	1254.00
IUUC-Ptr-091563	Pan troglodytes	86.10	0.00e+00	1338.00
IUUC-Pan-092042	Papio anubis	86.35	0.00e+00	1325.00
IUUC-Psi-093306	Pelodiscus sinensis	77.69	0.00e+00	1262.00
IUUC-Ppa-095694	Physcomitrella patens	41.31	2.00e-179	623.00
IUUC-Pfo-096800	Poecilia formosa	66.07	0.00e+00	1090.00
IUUC-Pab-098356	Pongo abelii	85.84	0.00e+00	1335.00
IUUC-Pva-102246	Pteropus vampyrus	81.67	0.00e+00	1216.00
IUUC-Rno-105195	Rattus norvegicus	85.21	0.00e+00	1303.00
IUUC-Sha-107056	Sarcophilus harrisii	83.84	0.00e+00	1300.00
IUUC-Smo-109240	Selaginella moellendorffii	40.05	4.00e-151	528.00
IUUC-Sar-113301	Sorex araneus	62.75	5.00e-96	345.00
IUUC-Ssc-116040	Sus scrofa	98.80	1.00e-146	512.00
IUUC-Tgu-117127	Taeniopygia guttata	73.06	0.00e+00	1149.00
IUUC-Tru-118663	Takifugu rubripes	65.05	0.00e+00	1066.00
IUUC-Tsy-119207	Tarsius syrichta	77.56	0.00e+00	679.00
IUUC-Tni-120705	Tetraodon nigroviridis	64.16	0.00e+00	1058.00
IUUC-Tbe-127434	Tupaia belangeri	77.27	0.00e+00	759.00
IUUC-Ttr-128937	Tursiops truncatus	85.34	0.00e+00	1320.00
IUUC-Vpa-130518	Vicugna pacos	81.06	0.00e+00	1203.00
IUUC-Xtr-131879	Xenopus tropicalis	70.55	0.00e+00	1131.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence