iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037619

Ensembl Protein ID

ENSFALP00000005214.1

UniProt Accession

U3JR10; U3JR10_FICAL

Genbank Protein ID

ENSFALP00000005214

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000355

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000005003.1	ENSFALT00000005239.1	ENSFALP00000005214.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.60e-17	63.3	63	128
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.80e-09	34.7	162	193

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k ++ +ei+d + ++ ++l+kF Y+++l++
   Q: 63   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QKLIEIRDFDGDAIEDLVKFAYSSRLTL 128
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ f++ hF+
   Q: 162  PSNCLAVRAFAESHNRIDLMDMADQFACEHFT 193
           89*****************************7 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MASESMVPEQ AKQHLIKGKR RQQQQTRPSN SDGDEDVFVF EANEAWKDFH SSLLHFFEAG 60
ELCDVTLKVG SKLISCHKLV LACVIPYFRA MFLSEMAEAK QKLIEIRDFD GDAIEDLVKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG AATCCATGGT TCCTGAGCAG GCAAAACAAC ATCTGATAAA GGGAAAAAGG 60
CGGCAGCAGC AGCAAACTCG GCCTTCCAAC AGCGATGGGG ATGAGGATGT CTTCGTGTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

fab:101813618

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	90.63	0.00e+00	1154.00
IUUC-Atr-002726	Amborella trichopoda	37.45	3.00e-43	170.00
IUUC-Apl-003978	Anas platyrhynchos	93.84	0.00e+00	1199.00
IUUC-Aca-004958	Anolis carolinensis	87.52	0.00e+00	1115.00
IUUC-Ame-011139	Astyanax mexicanus	82.98	0.00e+00	1079.00
IUUC-Bta-013142	Bos taurus	90.11	0.00e+00	1147.00
IUUC-Cel-018551	Caenorhabditis elegans	40.51	1.00e-129	457.00
IUUC-Cja-019650	Callithrix jacchus	90.00	0.00e+00	1173.00
IUUC-Cfa-021046	Canis familiaris	90.61	0.00e+00	1152.00
IUUC-Cpo-022445	Cavia porcellus	89.18	0.00e+00	1106.00
IUUC-Csa-023642	Chlorocebus sabaeus	90.48	0.00e+00	1177.00
IUUC-Cho-025012	Choloepus hoffmanni	75.04	0.00e+00	849.00
IUUC-Dre-027723	Danio rerio	81.54	0.00e+00	1068.00
IUUC-Dno-028964	Dasypus novemcinctus	90.59	0.00e+00	966.00
IUUC-Dor-030899	Dipodomys ordii	78.15	1.00e-128	453.00
IUUC-Ete-032815	Echinops telfairi	87.90	0.00e+00	1134.00
IUUC-Eca-034162	Equus caballus	90.31	0.00e+00	1134.00
IUUC-Eeu-034660	Erinaceus europaeus	89.16	0.00e+00	1132.00
IUUC-Fca-035659	Felis catus	90.47	0.00e+00	1152.00
IUUC-Fox-037999	Fusarium oxysporum	31.17	4.00e-08	51.20
IUUC-Gmo-038546	Gadus morhua	84.63	0.00e+00	1046.00
IUUC-Ggr-040041	Gaeumannomyces graminis	31.97	2.00e-07	49.70
IUUC-Gga-040770	Gallus gallus	94.33	0.00e+00	1182.00
IUUC-Gac-042557	Gasterosteus aculeatus	80.06	0.00e+00	1046.00
IUUC-Ggo-044741	Gorilla gorilla	90.48	0.00e+00	1177.00
IUUC-Hsa-046025	Homo sapiens	90.48	0.00e+00	1177.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	92.90	0.00e+00	1057.00
IUUC-Loc-052834	Lepisosteus oculatus	84.25	0.00e+00	1025.00
IUUC-Laf-054513	Loxodonta africana	89.01	0.00e+00	1152.00
IUUC-Mcc-054707	Macaca mulatta	90.32	0.00e+00	1173.00
IUUC-Meu-056779	Macropus eugenii	90.19	0.00e+00	1162.00
IUUC-Mtr-058180	Medicago truncatula	34.10	1.00e-37	151.00
IUUC-Mga-059676	Meleagris gallopavo	93.84	0.00e+00	1179.00
IUUC-Mmr-061359	Microcebus murinus	88.71	0.00e+00	1125.00
IUUC-Mdo-062527	Monodelphis domestica	89.41	0.00e+00	1152.00
IUUC-Mmu-063112	Mus musculus	86.19	0.00e+00	1139.00
IUUC-Mac-064682	Musa acuminata	35.90	6.00e-42	165.00
IUUC-Mpu-065800	Mustela putorius furo	90.47	0.00e+00	1150.00
IUUC-Mlu-067536	Myotis lucifugus	88.11	0.00e+00	1103.00
IUUC-Nle-069397	Nomascus leucogenys	90.48	0.00e+00	1177.00
IUUC-Opr-070599	Ochotona princeps	89.63	0.00e+00	953.00
IUUC-Ont-072580	Oreochromis niloticus	81.36	0.00e+00	1061.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.76	0.00e+00	1172.00
IUUC-Ocu-074026	Oryctolagus cuniculus	90.15	0.00e+00	1129.00
IUUC-Ola-086776	Oryzias latipes	80.16	0.00e+00	1009.00
IUUC-Oga-088651	Otolemur garnettii	89.86	0.00e+00	1140.00
IUUC-Oar-089567	Ovis aries	88.98	0.00e+00	1122.00
IUUC-Ptr-091564	Pan troglodytes	90.48	0.00e+00	1177.00
IUUC-Pan-092578	Papio anubis	90.48	0.00e+00	1177.00
IUUC-Psi-093635	Pelodiscus sinensis	91.74	0.00e+00	1130.00
IUUC-Pma-094660	Petromyzon marinus	62.67	0.00e+00	765.00
IUUC-Pfo-097507	Poecilia formosa	80.59	0.00e+00	991.00
IUUC-Pab-098025	Pongo abelii	90.48	0.00e+00	1177.00
IUUC-Pca-101046	Procavia capensis	81.64	4.00e-172	597.00
IUUC-Ppe-101154	Prunus persica	33.07	1.00e-38	154.00
IUUC-Pva-102359	Pteropus vampyrus	93.64	0.00e+00	872.00
IUUC-Rno-105750	Rattus norvegicus	87.30	0.00e+00	1125.00
IUUC-Sha-107513	Sarcophilus harrisii	91.77	0.00e+00	1182.00
IUUC-Sly-111482	Solanum lycopersicum	33.07	4.00e-42	166.00
IUUC-Stu-112032	Solanum tuberosum	33.46	1.00e-42	167.00
IUUC-Sar-113616	Sorex araneus	68.49	1.00e-113	403.00
IUUC-Ssc-116205	Sus scrofa	90.43	0.00e+00	965.00
IUUC-Tgu-117435	Taeniopygia guttata	98.38	0.00e+00	1251.00
IUUC-Tru-118709	Takifugu rubripes	80.10	0.00e+00	1055.00
IUUC-Tsy-119466	Tarsius syrichta	93.43	0.00e+00	1061.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.13	0.00e+00	1050.00
IUUC-Tca-120913	Theobroma cacao	34.40	3.00e-35	143.00
IUUC-Tbe-127704	Tupaia belangeri	91.06	0.00e+00	1014.00
IUUC-Ttr-128892	Tursiops truncatus	92.22	0.00e+00	882.00
IUUC-Vpa-130545	Vicugna pacos	91.00	0.00e+00	969.00
IUUC-Xtr-132289	Xenopus tropicalis	84.11	0.00e+00	1038.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence