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Tag Content
UUCD2 ID IUUC-Cfa-020753
UUCD1 version UUC-CaF-00273
Ensembl Protein ID ENSCAFP00000006958.4
UniProt Accession E2RBL8; E2RBL8_CANLF
Genbank Protein ID ENSCAFP00000006958
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03009785
Gene Name HECTD3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000004672.4 ENSCAFT00000007516.4 ENSCAFP00000006958.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 8.10e-77 259.2 243 569
Active Site
Position(s) Description Evidence
539 Glycyl thioester intermediate {ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 8    rlevefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnpdsglknp..ehlklFeflGrllgkalqdgrll 88
            +e++f  E  +d+gG +r+ la +s+el+ ++      l++f++++n+ + +  ++d+++ np  + +  +e++G+l+g al+ +++l
   Q: 243  WWECKFIAEGIIDQGGGFRDSLADMSEELCPSSadtpvpLPFFVRTANQGNGTGEARDMYVPNPscRDFAKYEWIGQLMGAALRGKEFL 331
           355*****************************9999*99**********************9999999********************* PP
   S: 89   dlplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfsvseei...lgetkeeeLkpgGenipVtneNkeeY 173
            l l+ +++k+l g+++s+ +d+++vd+ l+k l+ ++      +++++++++f ++ +    l++++++eL+pgG+ i V +e+++++
   Q: 332  VLALPGFVWKQLSGEEVSWsKDFPAVDSVLVKLLEVMEG-----MDKETFEFKFGKELTFttvLSDQQVVELIPGGAGIVVGYEDRSRF 415
           **************************************5.....56666777777443334449************************* PP
   S: 174  vklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           ++lv + rl+e  keqv+a+++G+ +v+p+ +l+l+t++ele  +cG++e++v++l+k t++++ +++++  +q+Fwe+l++f++e+r+
   Q: 416  IQLVQKTRLEE-SKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFED-FEPSDTRVQYFWEALNNFTNEDRS 502
           **********9.9*************************************************76.************************ PP
   S: 263  afLqFvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +fL+FvTg+srlP+        r++++++   ++++d lP+s+TC ++L LP+Y s + ++ekL+yA  ++ +++
   Q: 503  RFLRFVTGRSRLPA--------RIYIYPDklgYETTDALPESSTCSSTLFLPHYASAKLCEEKLRYAAYNCVAID 569
           *************5........6667777799999**********************************998776 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MKKGTIVKKL LLTVDTTDDN FMPKRVVIYG GEGDNLKKLS DVSIDETLIG DVCVLEDMTV 60
HLPVIEIRIV ECRDDGIDVR LRGIKIKSSR QRELGLNADL FQPTSLVRYP RLEGTDPEVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020753|E3,HECT|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGCAGCTGG CGGAACACCT GGGCGACTGC GGGCTGAACG AGGGCTGGCT GCTGGTGTGC 60
CGCCCGGCGG AGGGCGGGGC CCGCCTCGTA CCCATCGACA CCCCAGACCA CCTCCAGCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020753|E3,HECT|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
PROSITE

PS51284--DOC
PS50237--HECT
Pfam

PF00632--HECT
SMART

SM00119--HECTc
Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001229 Ailuropoda melanoleuca 99.31 0.00e+00 1177.00
IUUC-Apl-003715 Anas platyrhynchos 88.21 0.00e+00 1053.00
IUUC-Aca-004377 Anolis carolinensis 87.18 0.00e+00 1042.00
IUUC-Ame-011918 Astyanax mexicanus 75.56 0.00e+00 913.00
IUUC-Bta-012736 Bos taurus 98.79 0.00e+00 1177.00
IUUC-Cja-019926 Callithrix jacchus 98.61 0.00e+00 1174.00
IUUC-Cpo-021415 Cavia porcellus 97.57 0.00e+00 1163.00
IUUC-Csa-023096 Chlorocebus sabaeus 98.44 0.00e+00 1174.00
IUUC-Dre-028746 Danio rerio 78.51 0.00e+00 929.00
IUUC-Dno-029293 Dasypus novemcinctus 97.36 0.00e+00 1073.00
IUUC-Dor-031113 Dipodomys ordii 97.75 0.00e+00 1171.00
IUUC-Ete-032601 Echinops telfairi 88.91 0.00e+00 1034.00
IUUC-Eca-034198 Equus caballus 98.09 0.00e+00 1169.00
IUUC-Eeu-034708 Erinaceus europaeus 97.77 0.00e+00 909.00
IUUC-Fca-035478 Felis catus 99.65 0.00e+00 1184.00
IUUC-Fal-037366 Ficedula albicollis 87.35 0.00e+00 1046.00
IUUC-Gmo-039020 Gadus morhua 76.12 0.00e+00 938.00
IUUC-Gga-040332 Gallus gallus 87.69 0.00e+00 1043.00
IUUC-Gac-042336 Gasterosteus aculeatus 77.72 0.00e+00 956.00
IUUC-Ggo-045382 Gorilla gorilla 98.61 0.00e+00 1174.00
IUUC-Hsa-046562 Homo sapiens 98.61 0.00e+00 1174.00
IUUC-Itr-048208 Ictidomys tridecemlineatus 97.92 0.00e+00 1166.00
IUUC-Lch-049606 Latimeria chalumnae 71.95 0.00e+00 699.00
IUUC-Loc-052448 Lepisosteus oculatus 66.90 0.00e+00 778.00
IUUC-Laf-054507 Loxodonta africana 97.23 0.00e+00 1157.00
IUUC-Mcc-055690 Macaca mulatta 98.44 0.00e+00 1174.00
IUUC-Meu-055970 Macropus eugenii 91.68 0.00e+00 1082.00
IUUC-Mga-059654 Meleagris gallopavo 88.04 0.00e+00 1048.00
IUUC-Mmr-061069 Microcebus murinus 98.44 0.00e+00 1173.00
IUUC-Mdo-062547 Monodelphis domestica 92.20 0.00e+00 795.00
IUUC-Mmu-063096 Mus musculus 97.75 0.00e+00 1164.00
IUUC-Mpu-065846 Mustela putorius furo 99.65 0.00e+00 1183.00
IUUC-Mlu-067992 Myotis lucifugus 97.92 0.00e+00 1164.00
IUUC-Nle-069565 Nomascus leucogenys 98.67 0.00e+00 1066.00
IUUC-Opr-070853 Ochotona princeps 82.93 0.00e+00 948.00
IUUC-Ont-071628 Oreochromis niloticus 77.99 0.00e+00 928.00
IUUC-Ocu-074094 Oryctolagus cuniculus 98.27 0.00e+00 1171.00
IUUC-Ola-087384 Oryzias latipes 78.37 0.00e+00 971.00
IUUC-Oga-088224 Otolemur garnettii 98.27 0.00e+00 1172.00
IUUC-Oar-090043 Ovis aries 97.92 0.00e+00 1162.00
IUUC-Ptr-090852 Pan troglodytes 98.44 0.00e+00 1171.00
IUUC-Pan-092787 Papio anubis 98.44 0.00e+00 1175.00
IUUC-Psi-092986 Pelodiscus sinensis 75.87 0.00e+00 867.00
IUUC-Pma-094416 Petromyzon marinus 41.99 7.00e-131 461.00
IUUC-Pfo-096720 Poecilia formosa 78.51 0.00e+00 969.00
IUUC-Pab-098325 Pongo abelii 98.71 0.00e+00 796.00
IUUC-Pca-100885 Procavia capensis 80.56 0.00e+00 913.00
IUUC-Pva-102829 Pteropus vampyrus 78.39 4.00e-159 555.00
IUUC-Rno-104882 Rattus norvegicus 97.92 0.00e+00 1165.00
IUUC-Sha-106811 Sarcophilus harrisii 90.09 7.00e-116 410.00
IUUC-Sar-113020 Sorex araneus 83.14 0.00e+00 709.00
IUUC-Ssc-115436 Sus scrofa 98.72 3.00e-87 315.00
IUUC-Tgu-117042 Taeniopygia guttata 87.69 0.00e+00 1049.00
IUUC-Tru-118419 Takifugu rubripes 76.95 0.00e+00 921.00
IUUC-Tsy-118829 Tarsius syrichta 97.59 3.00e-171 595.00
IUUC-Tni-120410 Tetraodon nigroviridis 60.83 0.00e+00 683.00
IUUC-Tbe-128113 Tupaia belangeri 98.69 0.00e+00 782.00
IUUC-Ttr-128167 Tursiops truncatus 93.07 0.00e+00 1080.00
IUUC-Xtr-132910 Xenopus tropicalis 74.35 0.00e+00 843.00
Created Date 25-Jun-2017

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