iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117042

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01031128

Gene Name

LOC100222219

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000007801.1	ENSTGUT00000008138.1	ENSTGUP00000008053.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-76	257.9	509	834

Active Site

Position(s)	Description	Evidence
804	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 9    levefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnpdsglknp..ehlklFeflGrllgkalqdgrlld 89
           +e++f  E  +d+gG +r+ la +s+el+ ++      l++f++++n+ + +  ++d+++ np  + +  +e++G+++g al+ +++l 
   Q: 509  WECKFIAEGIIDQGGGFRDSLADMSEELCPSSadtpvpLPFFVRTSNQGNGTGEARDMYVPNPscKDFPKYEWIGQIMGAALRGKEFLV 597
           45*****************************9999*99**********************9998889999******************* PP
   S: 90   lplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfs...vseeilgetkeeeLkpgGenipVtneNkeeYv 174
           l l+ +++k+l g+++s+ +d+++vd+ l+k l+ ++ +     ++ +++++f    + +++l++++ +eL+p+G+n+ V +e+++e++
   Q: 598  LALPGFVWKQLTGEEVSWsKDFPAVDSVLVKLLEVMEVM-----DKDTFEFKFGnelTYTTVLSDQRMVELIPNGSNTAVRYEDRKEFI 681
           *************************************77.....333455555533445567999************************ PP
   S: 175  klvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           +lv ++rl+e  keq+ a+++G+ +v+p+ +l+l+t++ele  +cG++e++v++lkk t++++ +++++  +q+Fwe+l++f++e+r++
   Q: 682  RLVQKARLEE-SKEQIMAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALKKLTRFED-FEPQDTRVQYFWEALNNFTNEDRSR 768
           *********9.9*************************************************76.************************* PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           fL+FvTg+srlP+        r++++++   ++++d lP+s+TC ++L LP+Y + ++++ekL+yA  ++ +++
   Q: 769  FLRFVTGRSRLPA--------RIYIYPDkmgSETTDALPESSTCSSTLFLPNYATAKVCEEKLRYAAYNCVAID 834
           ************5........66677767888899*********************************998776 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

EAPHQVLGRL RFLLQCSECF RRARALPAAL CYVPREVQYK ICKDPAAAAA AAARSLLSVW 60
DSPGPARGGK RAARATIEVR KGGCLRATGE EYCNSAGLWV KLSKEQLEEY RSGCDLEEGW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGCGCCGC ACCAGGTGCT GGGCCGGCTG CGGTTCCTGC TGCAGTGCAG CGAGTGCTTC 60
CGCCGCGCCC GGGCGCTGCC CGCCGCGCTC TGCTACGTGC CGCGGGAGGT GCAGTACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	79.77	0.00e+00	1397.00
IUUC-Apl-003715	Anas platyrhynchos	97.29	0.00e+00	1472.00
IUUC-Aca-004377	Anolis carolinensis	86.82	0.00e+00	1503.00
IUUC-Ame-011918	Astyanax mexicanus	68.46	0.00e+00	1202.00
IUUC-Bta-012736	Bos taurus	80.12	0.00e+00	1414.00
IUUC-Cja-019926	Callithrix jacchus	79.88	0.00e+00	1409.00
IUUC-Cfa-020753	Canis familiaris	87.69	0.00e+00	1072.00
IUUC-Cpo-021415	Cavia porcellus	79.42	0.00e+00	1400.00
IUUC-Csa-023096	Chlorocebus sabaeus	79.65	0.00e+00	1404.00
IUUC-Dre-028746	Danio rerio	75.15	0.00e+00	1285.00
IUUC-Dno-029293	Dasypus novemcinctus	87.19	0.00e+00	983.00
IUUC-Dor-031113	Dipodomys ordii	87.66	0.00e+00	1132.00
IUUC-Ete-032601	Echinops telfairi	75.84	0.00e+00	1233.00
IUUC-Eca-034198	Equus caballus	78.48	0.00e+00	1395.00
IUUC-Eeu-034708	Erinaceus europaeus	88.17	0.00e+00	836.00
IUUC-Fca-035478	Felis catus	80.84	0.00e+00	1399.00
IUUC-Fal-037366	Ficedula albicollis	95.29	0.00e+00	1583.00
IUUC-Gmo-039020	Gadus morhua	78.78	0.00e+00	1076.00
IUUC-Gga-040332	Gallus gallus	96.56	0.00e+00	1647.00
IUUC-Gac-042336	Gasterosteus aculeatus	75.18	0.00e+00	1332.00
IUUC-Ggo-045382	Gorilla gorilla	79.65	0.00e+00	1404.00
IUUC-Hsa-046562	Homo sapiens	79.65	0.00e+00	1404.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	79.77	0.00e+00	1405.00
IUUC-Lch-049606	Latimeria chalumnae	71.45	0.00e+00	896.00
IUUC-Loc-052448	Lepisosteus oculatus	67.87	0.00e+00	1165.00
IUUC-Laf-054507	Loxodonta africana	79.09	0.00e+00	1411.00
IUUC-Mcc-055690	Macaca mulatta	79.53	0.00e+00	1403.00
IUUC-Meu-055970	Macropus eugenii	80.66	0.00e+00	1377.00
IUUC-Mga-059654	Meleagris gallopavo	98.08	0.00e+00	1458.00
IUUC-Mmr-061069	Microcebus murinus	79.77	0.00e+00	1407.00
IUUC-Mdo-062547	Monodelphis domestica	90.07	0.00e+00	776.00
IUUC-Mmu-063096	Mus musculus	79.65	0.00e+00	1413.00
IUUC-Mpu-065846	Mustela putorius furo	79.88	0.00e+00	1409.00
IUUC-Mlu-067992	Myotis lucifugus	83.70	0.00e+00	1362.00
IUUC-Nle-069565	Nomascus leucogenys	78.73	0.00e+00	1305.00
IUUC-Opr-070853	Ochotona princeps	73.88	0.00e+00	914.00
IUUC-Ont-071628	Oreochromis niloticus	74.79	0.00e+00	1298.00
IUUC-Ocu-074094	Oryctolagus cuniculus	79.65	0.00e+00	1407.00
IUUC-Ola-087384	Oryzias latipes	74.15	0.00e+00	1330.00
IUUC-Oga-088224	Otolemur garnettii	79.77	0.00e+00	1411.00
IUUC-Oar-090043	Ovis aries	78.27	0.00e+00	1342.00
IUUC-Ptr-090852	Pan troglodytes	79.42	0.00e+00	1397.00
IUUC-Pan-092787	Papio anubis	79.53	0.00e+00	1404.00
IUUC-Psi-092986	Pelodiscus sinensis	77.50	0.00e+00	1041.00
IUUC-Pma-094416	Petromyzon marinus	41.46	0.00e+00	630.00
IUUC-Pfo-096720	Poecilia formosa	74.71	0.00e+00	1340.00
IUUC-Pab-098325	Pongo abelii	77.03	0.00e+00	1055.00
IUUC-Pca-100885	Procavia capensis	72.51	0.00e+00	1066.00
IUUC-Pva-102829	Pteropus vampyrus	66.32	0.00e+00	1105.00
IUUC-Rno-104882	Rattus norvegicus	80.00	0.00e+00	1411.00
IUUC-Sha-106811	Sarcophilus harrisii	83.02	2.00e-108	385.00
IUUC-Sar-113020	Sorex araneus	75.30	0.00e+00	654.00
IUUC-Ssc-115436	Sus scrofa	82.96	6.00e-137	479.00
IUUC-Tru-118419	Takifugu rubripes	72.67	0.00e+00	1247.00
IUUC-Tsy-118829	Tarsius syrichta	80.00	0.00e+00	843.00
IUUC-Tni-120410	Tetraodon nigroviridis	61.25	0.00e+00	1006.00
IUUC-Tbe-128113	Tupaia belangeri	87.99	0.00e+00	714.00
IUUC-Ttr-128167	Tursiops truncatus	76.02	0.00e+00	1318.00
IUUC-Xtr-132910	Xenopus tropicalis	70.65	0.00e+00	1169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence