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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046469
UUCD1 version UUC-HoS-00312
Ensembl Protein ID ENSP00000254816.1
UniProt Accession Q96LD4; Q96AD0; Q96GU5; Q9BRN7; TRI47_HUMAN
Genbank Protein ID AAK07687.1; EAW89332.1; AAH06153.1; AAH09225.2; AAH17299.1
Protein Name Tripartite motif-containing protein 47; Gene overexpressed in astrocytoma protein; RING finger protein 100
Genbank Nucleotide ID AY026763; AC087289; BC006153; BC009225; BC017299
Gene Name TRIM47; GOA; RNF100
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000132481.6 ENST00000254816.5 ENSP00000254816.1
ENSG00000132481.6 ENST00000585333.1 ENSP00000467645.1
ENSG00000132481.6 ENST00000587339.2 ENSP00000465010.2
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbcircBaseCircNetmiRTarBase
microRNATRANSFACTargetScanRepTar
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Information
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRIDmUbiSiDa
DNA Methylation
MethyCancerTCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/RING/RING RING 18248090
Classification
Family E-value Score Start End
E3 activity/RING/U-box 3.50e-05 25.4 7 76
E3 activity/RING/RING 3.70e-10 41.8 9 58
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/U-box
   S: 6    flCpIslelMrdPvvlpsGitydrssIek.wlasggk.........tcPvtrqpl.teedlvPnltlrrl 64
           f CpI le+ r+Pv+lp+G+ +  +++   w  +g +          cP++++p+ +  +l  n+tl +l
   Q: 7    FSCPICLEPLREPVTLPCGHNFCLACLGAlWPHRGASgaggpggaaRCPLCQEPFpDGLQLRKNHTLSEL 76
           99***********************997624444444667999999*********7778899**999776 PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkw....pglknssskefrCPlCr 46
           C+iCle++++ p++lpCgH f++ Cl   w            +++rCPlC+
   Q: 9    CPICLEPLRE-PVTLPCGHNFCLACLgALWphrgASGAGGPGGAARCPLCQ 58
           ********99.***************7777777744444457788*****7 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MDGSGPFSCP ICLEPLREPV TLPCGHNFCL ACLGALWPHR GASGAGGPGG AARCPLCQEP 60
FPDGLQLRKN HTLSELLQLR QGSGPGSGPG PAPALAPEPS APSALPSVPE PSAPCAPEPW 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046469|E3,RING;E3,U-box|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCGGCGCCC TGGGCGGCCG CGGAGTCATG GACGGCAGTG GACCCTTCAG CTGCCCCATC 60
TGCCTAGAGC CACTCCGGGA GCCGGTGACG CTGCCCTGCG GCCACAACTT CTGTCTCGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046469|E3,RING;E3,U-box|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0488--Methylation
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001870--B30.2/SPRY
IPR013320--ConA-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00643--zf-B_box
SMART

SM00336--BBOX
SM00184--RING
Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
KEGG hsa:91107
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001364 Ailuropoda melanoleuca 89.46 0.00e+00 756.00
IUUC-Aca-005308 Anolis carolinensis 54.23 4.00e-106 377.00
IUUC-Bta-013256 Bos taurus 88.00 0.00e+00 855.00
IUUC-Cja-018778 Callithrix jacchus 87.99 0.00e+00 894.00
IUUC-Cfa-020705 Canis familiaris 90.53 5.00e-98 352.00
IUUC-Cpo-021797 Cavia porcellus 84.11 0.00e+00 892.00
IUUC-Csa-023409 Chlorocebus sabaeus 93.91 0.00e+00 955.00
IUUC-Dor-030726 Dipodomys ordii 86.14 0.00e+00 947.00
IUUC-Eca-033641 Equus caballus 90.58 3.00e-180 624.00
IUUC-Eeu-034657 Erinaceus europaeus 90.57 6.00e-107 380.00
IUUC-Fca-036282 Felis catus 76.79 4.00e-179 621.00
IUUC-Fal-036823 Ficedula albicollis 55.96 5.00e-121 427.00
IUUC-Gga-040334 Gallus gallus 54.92 8.00e-118 416.00
IUUC-Ggo-044515 Gorilla gorilla 97.81 0.00e+00 996.00
IUUC-Itr-048949 Ictidomys tridecemlineatus 77.12 0.00e+00 804.00
IUUC-Laf-054448 Loxodonta africana 86.52 0.00e+00 940.00
IUUC-Mcc-054916 Macaca mulatta 94.06 0.00e+00 957.00
IUUC-Meu-056438 Macropus eugenii 79.15 0.00e+00 939.00
IUUC-Mga-059813 Meleagris gallopavo 54.81 4.00e-138 484.00
IUUC-Mmr-060614 Microcebus murinus 85.00 0.00e+00 878.00
IUUC-Mdo-062464 Monodelphis domestica 77.98 0.00e+00 850.00
IUUC-Mmu-063631 Mus musculus 88.01 0.00e+00 943.00
IUUC-Mpu-066154 Mustela putorius furo 90.50 0.00e+00 627.00
IUUC-Mlu-067203 Myotis lucifugus 89.29 0.00e+00 693.00
IUUC-Nle-069591 Nomascus leucogenys 96.86 0.00e+00 729.00
IUUC-Opr-070649 Ochotona princeps 91.21 0.00e+00 781.00
IUUC-Oan-073653 Ornithorhynchus anatinus 84.91 6.00e-104 371.00
IUUC-Ocu-074752 Oryctolagus cuniculus 88.85 0.00e+00 866.00
IUUC-Oga-088971 Otolemur garnettii 90.91 0.00e+00 968.00
IUUC-Oar-089868 Ovis aries 76.50 2.00e-142 498.00
IUUC-Ptr-091634 Pan troglodytes 96.57 0.00e+00 997.00
IUUC-Pan-092126 Papio anubis 92.32 0.00e+00 951.00
IUUC-Psi-093955 Pelodiscus sinensis 58.60 1.00e-114 405.00
IUUC-Pfo-096134 Poecilia formosa 29.57 2.00e-52 200.00
IUUC-Pab-097985 Pongo abelii 94.06 0.00e+00 961.00
IUUC-Pva-102360 Pteropus vampyrus 81.09 0.00e+00 808.00
IUUC-Rno-104845 Rattus norvegicus 87.07 0.00e+00 910.00
IUUC-Sha-107613 Sarcophilus harrisii 79.90 5.00e-172 597.00
IUUC-Ssc-116292 Sus scrofa 89.81 0.00e+00 808.00
IUUC-Tgu-116986 Taeniopygia guttata 52.05 1.00e-165 577.00
IUUC-Tbe-127869 Tupaia belangeri 77.24 5.00e-163 567.00
Created Date 25-Jun-2017

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