iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tgu-117050

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01011590

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000005854.1	ENSTGUT00000006148.1	ENSTGUP00000006089.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-21	75.5	47	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.80e-09	36.2	148	175

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e+ ah++vLaa+S++F+a+f++e++es+  ++v ik+v+   +r l++++Yt +++ +e
   Q: 47   CDVTIVAEDMEIAAHRVVLAACSPYFHAMFTGEMSESR-AKKVRIKEVDGWTLRMLIDYIYTAEIQVTE 114
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 3    NclgilrfAdlydcpdLkdaaldfilkh 30
           Nclgi++fAd++ c+dL ++a++++ kh
   Q: 148  NCLGIRAFADMHACTDLLSKANTYAGKH 175
           ************************9888 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

CTKLCHQKPL DLKEDNTEIH CPITVNPWHM KKAFKVMNEL RSQNLLCDVT IVAEDMEIAA 60
HRVVLAACSP YFHAMFTGEM SESRAKKVRI KEVDGWTLRM LIDYIYTAEI QVTEENVQVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTACCAAAC TTTGCCATCA GAAGCCCTTG GATCTGAAAG AAGATAACAC CGAAATTCAC 60
TGTCCTATTA CAGTAAATCC ATGGCACATG AAGAAAGCTT TTAAAGTTAT GAATGAATTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	91.62	0.00e+00	1094.00
IUUC-Apl-003260	Anas platyrhynchos	98.12	0.00e+00	1145.00
IUUC-Aca-005143	Anolis carolinensis	87.01	0.00e+00	1076.00
IUUC-Cja-018942	Callithrix jacchus	91.62	0.00e+00	1095.00
IUUC-Cfa-020886	Canis familiaris	91.62	0.00e+00	1095.00
IUUC-Cpo-022543	Cavia porcellus	91.45	0.00e+00	1093.00
IUUC-Csa-023088	Chlorocebus sabaeus	91.62	0.00e+00	1095.00
IUUC-Dre-028082	Danio rerio	81.37	0.00e+00	974.00
IUUC-Dno-029873	Dasypus novemcinctus	89.46	0.00e+00	1074.00
IUUC-Dor-030460	Dipodomys ordii	73.16	0.00e+00	799.00
IUUC-Dse-031229	Dothistroma septosporum	34.88	2.00e-08	52.00
IUUC-Dme-032172	Drosophila melanogaster	60.36	0.00e+00	660.00
IUUC-Eca-033798	Equus caballus	90.94	0.00e+00	1088.00
IUUC-Eeu-034824	Erinaceus europaeus	84.71	0.00e+00	923.00
IUUC-Fca-036455	Felis catus	91.62	0.00e+00	1095.00
IUUC-Fal-037293	Ficedula albicollis	99.46	0.00e+00	1088.00
IUUC-Gmo-038811	Gadus morhua	78.01	0.00e+00	859.00
IUUC-Gga-040805	Gallus gallus	97.26	0.00e+00	1138.00
IUUC-Gac-041979	Gasterosteus aculeatus	80.28	0.00e+00	863.00
IUUC-Ggo-044620	Gorilla gorilla	86.67	0.00e+00	1031.00
IUUC-Hsa-046265	Homo sapiens	91.45	0.00e+00	1093.00
IUUC-Lch-049939	Latimeria chalumnae	82.39	0.00e+00	964.00
IUUC-Loc-052780	Lepisosteus oculatus	85.64	0.00e+00	1022.00
IUUC-Laf-053800	Loxodonta africana	91.45	0.00e+00	1093.00
IUUC-Mcc-055732	Macaca mulatta	90.58	0.00e+00	1079.00
IUUC-Meu-056011	Macropus eugenii	92.08	0.00e+00	1015.00
IUUC-Mmr-061067	Microcebus murinus	90.10	0.00e+00	1076.00
IUUC-Mdo-062977	Monodelphis domestica	91.11	0.00e+00	1085.00
IUUC-Mmu-064035	Mus musculus	90.81	0.00e+00	1071.00
IUUC-Mpu-066726	Mustela putorius furo	91.79	0.00e+00	1097.00
IUUC-Mlu-067020	Myotis lucifugus	91.28	0.00e+00	1091.00
IUUC-Nle-069456	Nomascus leucogenys	91.45	0.00e+00	1093.00
IUUC-Opr-071130	Ochotona princeps	82.39	0.00e+00	956.00
IUUC-Ont-072219	Oreochromis niloticus	80.68	0.00e+00	916.00
IUUC-Oan-073699	Ornithorhynchus anatinus	90.77	0.00e+00	932.00
IUUC-Ocu-074045	Oryctolagus cuniculus	91.28	0.00e+00	1090.00
IUUC-Oga-088494	Otolemur garnettii	91.45	0.00e+00	1093.00
IUUC-Oar-089645	Ovis aries	91.45	0.00e+00	1092.00
IUUC-Ptr-091063	Pan troglodytes	91.45	0.00e+00	1093.00
IUUC-Psi-093946	Pelodiscus sinensis	91.82	0.00e+00	1106.00
IUUC-Pma-094177	Petromyzon marinus	75.35	0.00e+00	790.00
IUUC-Pfo-096817	Poecilia formosa	80.17	0.00e+00	934.00
IUUC-Pab-097768	Pongo abelii	91.45	0.00e+00	1092.00
IUUC-Pca-100607	Procavia capensis	75.00	0.00e+00	764.00
IUUC-Pva-102218	Pteropus vampyrus	85.81	0.00e+00	1012.00
IUUC-Rno-105250	Rattus norvegicus	91.11	0.00e+00	1087.00
IUUC-Sar-113249	Sorex araneus	91.32	0.00e+00	1075.00
IUUC-Sre-115091	Sporisorium reilianum	53.12	5.40e-01	29.60
IUUC-Ssc-115423	Sus scrofa	91.62	0.00e+00	1094.00
IUUC-Tru-118239	Takifugu rubripes	79.56	0.00e+00	954.00
IUUC-Tsy-119377	Tarsius syrichta	78.63	0.00e+00	938.00
IUUC-Tni-120122	Tetraodon nigroviridis	80.29	0.00e+00	862.00
IUUC-Vpa-130707	Vicugna pacos	88.01	0.00e+00	824.00
IUUC-Xtr-132035	Xenopus tropicalis	84.79	0.00e+00	1038.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence