iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091348

Ensembl Protein ID

ENSPTRP00000028526.3

UniProt Accession

H2QQH6; H2QQH6_PANTR

Genbank Protein ID

ENSPTRP00000028526

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AACZ03030893

Gene Name

ING2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000016631.3	ENSPTRT00000030886.3	ENSPTRP00000028526.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.30e-09	37.3	173	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr
   Q: 173  TYC-LCNQVSYGE--MIGCDNeqCPiEWFHFSCVSLT---YKPKGK-WYCPKCR 219
           69*.*******99..*****999*99***********...888886.******8 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MDQDGDQQLG PSRILAPQTL KEIDDVYEKY KKEDDLNQKK RLQQLLQRAL INSQELGDEK 60
IQIVTQMLEL VENRARQMEL HSQCFQDPAE SERASDKAKM DSSQPERSSR RPRRQRTSES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCAGG ACGGCGATCA GCAGCTCGGA CCGTCGCGGA TCCTGGCTCC GCGTAGGTTC 60
CGGGACGTGT CACTTCCGGG CTTCAGGAGG AAGTGGGTTG GTTGACTGGG CAACCGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028639--ING2
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM00249--PHD

Gene Ontology

GO:0016602--C:CCAAT-binding factor complex
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005886--C:plasma membrane
GO:0016580--C:Sin3 complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035091--F:phosphatidylinositol binding
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0030317--P:flagellated sperm motility
GO:0048133--P:male germ-line stem cell asymmetric division
GO:0007141--P:male meiosis I
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0031065--P:positive regulation of histone deacetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0030511--P:positive regulation of transforming growth factor beta receptor signaling pathway
GO:2000772--P:regulation of cellular senescence
GO:0072520--P:seminiferous tubule development
GO:0007286--P:spermatid development

KEGG

ptr:461625

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002213	Ailuropoda melanoleuca	97.55	5.00e-89	320.00
IUUC-Apl-003705	Anas platyrhynchos	88.34	4.00e-90	323.00
IUUC-Aca-004990	Anolis carolinensis	83.41	2.00e-83	302.00
IUUC-Bta-012721	Bos taurus	98.04	1.00e-89	322.00
IUUC-Cja-018960	Callithrix jacchus	98.95	2.00e-82	298.00
IUUC-Cfa-020869	Canis familiaris	97.06	2.00e-88	318.00
IUUC-Cpo-021414	Cavia porcellus	95.59	2.00e-87	315.00
IUUC-Csa-023304	Chlorocebus sabaeus	100.00	7.00e-84	303.00
IUUC-Dno-029945	Dasypus novemcinctus	97.55	2.00e-89	322.00
IUUC-Dor-030141	Dipodomys ordii	96.57	3.00e-87	314.00
IUUC-Ete-032709	Echinops telfairi	95.96	4.00e-98	350.00
IUUC-Eca-033432	Equus caballus	98.53	2.00e-89	322.00
IUUC-Eeu-035285	Erinaceus europaeus	98.04	4.00e-89	320.00
IUUC-Fca-036467	Felis catus	98.04	5.00e-89	320.00
IUUC-Fal-036700	Ficedula albicollis	87.89	3.00e-89	321.00
IUUC-Gga-040175	Gallus gallus	87.56	3.00e-90	324.00
IUUC-Hsa-045837	Homo sapiens	100.00	7.00e-84	303.00
IUUC-Itr-049062	Ictidomys tridecemlineatus	97.55	7.00e-89	320.00
IUUC-Lch-049965	Latimeria chalumnae	82.96	4.00e-83	300.00
IUUC-Laf-053353	Loxodonta africana	97.31	2.00e-99	354.00
IUUC-Mcc-055155	Macaca mulatta	100.00	6.00e-74	269.00
IUUC-Meu-056470	Macropus eugenii	94.17	6.00e-94	337.00
IUUC-Mga-059570	Meleagris gallopavo	87.89	3.00e-89	320.00
IUUC-Mmr-061385	Microcebus murinus	99.47	2.00e-83	301.00
IUUC-Mdo-062144	Monodelphis domestica	94.62	2.00e-94	338.00
IUUC-Mmu-063215	Mus musculus	96.57	7.00e-89	320.00
IUUC-Mpu-065749	Mustela putorius furo	97.06	2.00e-88	318.00
IUUC-Mlu-067245	Myotis lucifugus	75.49	5.00e-81	293.00
IUUC-Nle-069968	Nomascus leucogenys	99.17	2.00e-92	331.00
IUUC-Ocu-074870	Oryctolagus cuniculus	98.53	4.00e-90	323.00
IUUC-Ola-087400	Oryzias latipes	89.02	3.00e-44	171.00
IUUC-Oga-088336	Otolemur garnettii	98.95	7.00e-83	300.00
IUUC-Oar-090136	Ovis aries	97.55	3.00e-89	321.00
IUUC-Pan-092819	Papio anubis	100.00	7.00e-84	303.00
IUUC-Psi-093854	Pelodiscus sinensis	86.21	2.00e-62	231.00
IUUC-Pab-098346	Pongo abelii	99.47	2.00e-83	301.00
IUUC-Pca-100278	Procavia capensis	95.07	2.00e-97	348.00
IUUC-Pva-103190	Pteropus vampyrus	99.02	4.00e-90	324.00
IUUC-Rno-104940	Rattus norvegicus	96.08	1.00e-87	315.00
IUUC-Sha-107533	Sarcophilus harrisii	94.17	3.00e-95	341.00
IUUC-Sar-113630	Sorex araneus	96.08	3.00e-88	317.00
IUUC-Ssc-115734	Sus scrofa	99.02	4.00e-90	323.00
IUUC-Tgu-117034	Taeniopygia guttata	88.34	1.00e-89	322.00
IUUC-Tsy-119494	Tarsius syrichta	99.51	8.00e-83	299.00
IUUC-Ttr-128442	Tursiops truncatus	98.53	1.00e-89	321.00
IUUC-Vpa-130063	Vicugna pacos	97.06	2.00e-88	318.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence