iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-005130

Ensembl Protein ID

ENSACAP00000004907.3

UniProt Accession

G1KDG5; G1KDG5_ANOCA

Protein Name

Uncharacterized protein

Gene Name

ITSN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000004697.3	ENSACAT00000005019.3	ENSACAP00000004907.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-68	225.5	1150	1201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +v+ +ydy aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+
   Q: 1150 QVIGMYDYIAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQMGLFPSNYVK 1201
           46779**********************..8889******..9*************8 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MAQFPTPFAG NLDIWGITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQLEFSI AMKLIKLKLQ GYQLPSSLPP IMKQPPIAIS SAPGFGIGGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATCTATTA GCAAGTTAGA GGTGTTTAAA CCATGGCTCA GTTTCCCACA CCTTTTGCGG 60
GTAAGTATTA ACATCATTTT CTTATACTAC TATTAAAGAG AAAACTATTT CACAACCAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000722	Aegilops tauschii	40.96	2.00e-13	72.00
IUUC-Aml-001218	Ailuropoda melanoleuca	88.40	0.00e+00	2239.00
IUUC-Apl-003335	Anas platyrhynchos	91.30	0.00e+00	2257.00
IUUC-Aly-005557	Arabidopsis lyrata	38.16	6.00e-11	63.50
IUUC-Ago-007935	Ashbya gossypii	34.33	2.00e-13	70.90
IUUC-Ame-011878	Astyanax mexicanus	75.73	0.00e+00	1912.00
IUUC-Bta-012863	Bos taurus	88.84	0.00e+00	2219.00
IUUC-Bdi-014016	Brachypodium distachyon	39.77	4.00e-13	70.50
IUUC-Cja-019012	Callithrix jacchus	89.61	0.00e+00	2209.00
IUUC-Cfa-020171	Canis familiaris	89.31	0.00e+00	2259.00
IUUC-Cpo-021352	Cavia porcellus	82.41	0.00e+00	2635.00
IUUC-Cho-024969	Choloepus hoffmanni	79.03	0.00e+00	1784.00
IUUC-Cin-025435	Ciona intestinalis	45.66	0.00e+00	994.00
IUUC-Csv-026290	Ciona savignyi	59.29	0.00e+00	785.00
IUUC-Dre-028623	Danio rerio	77.29	0.00e+00	1952.00
IUUC-Dno-030044	Dasypus novemcinctus	89.52	0.00e+00	2251.00
IUUC-Dor-030272	Dipodomys ordii	81.86	0.00e+00	1948.00
IUUC-Ete-032927	Echinops telfairi	96.19	0.00e+00	1021.00
IUUC-Eca-033469	Equus caballus	88.96	0.00e+00	2215.00
IUUC-Eeu-034977	Erinaceus europaeus	81.34	0.00e+00	989.00
IUUC-Fca-036419	Felis catus	88.76	0.00e+00	2241.00
IUUC-Fal-037236	Ficedula albicollis	88.92	0.00e+00	2235.00
IUUC-Gmo-039632	Gadus morhua	70.87	0.00e+00	1685.00
IUUC-Gga-040835	Gallus gallus	89.04	0.00e+00	2209.00
IUUC-Gac-041948	Gasterosteus aculeatus	72.60	0.00e+00	1815.00
IUUC-Hsa-045699	Homo sapiens	89.61	0.00e+00	2258.00
IUUC-Hvu-047530	Hordeum vulgare	39.77	1.00e-12	68.20
IUUC-Itr-048773	Ictidomys tridecemlineatus	85.70	0.00e+00	2154.00
IUUC-Lch-050502	Latimeria chalumnae	77.34	0.00e+00	1606.00
IUUC-Lpe-051250	Leersia perrieri	40.96	2.00e-13	71.60
IUUC-Loc-052613	Lepisosteus oculatus	81.40	0.00e+00	1980.00
IUUC-Laf-053608	Loxodonta africana	88.55	0.00e+00	2218.00
IUUC-Mcc-055720	Macaca mulatta	89.81	0.00e+00	2237.00
IUUC-Meu-056445	Macropus eugenii	82.58	0.00e+00	1636.00
IUUC-Mmr-061258	Microcebus murinus	89.53	0.00e+00	2224.00
IUUC-Mdo-062019	Monodelphis domestica	89.21	0.00e+00	2146.00
IUUC-Mmu-063885	Mus musculus	87.47	0.00e+00	2220.00
IUUC-Nle-069448	Nomascus leucogenys	77.51	0.00e+00	1096.00
IUUC-Opr-070441	Ochotona princeps	82.87	0.00e+00	1933.00
IUUC-Ont-071752	Oreochromis niloticus	73.14	0.00e+00	1813.00
IUUC-Oan-073390	Ornithorhynchus anatinus	84.81	0.00e+00	2113.00
IUUC-Ocu-073753	Oryctolagus cuniculus	85.99	0.00e+00	2808.00
IUUC-Ogu-078849	Oryza glumaepatula	40.96	2.00e-13	71.60
IUUC-Olo-080259	Oryza longistaminata	40.96	1.00e-13	72.40
IUUC-Ome-081199	Oryza meridionalis	40.96	2.00e-13	72.00
IUUC-Oni-082167	Oryza nivara	40.96	3.00e-13	70.90
IUUC-Oru-084541	Oryza rufipogon	40.96	3.00e-13	70.90
IUUC-Ola-087489	Oryzias latipes	49.84	0.00e+00	1168.00
IUUC-Oga-088602	Otolemur garnettii	89.49	0.00e+00	2250.00
IUUC-Oar-090195	Ovis aries	88.44	0.00e+00	2210.00
IUUC-Ptr-091363	Pan troglodytes	89.69	0.00e+00	2259.00
IUUC-Pan-092385	Papio anubis	89.03	0.00e+00	2218.00
IUUC-Ppa-095426	Physcomitrella patens	39.74	8.00e-12	65.90
IUUC-Pfo-097486	Poecilia formosa	73.55	0.00e+00	1844.00
IUUC-Pop-098963	Populus trichocarpa	39.51	2.00e-10	62.00
IUUC-Pca-100270	Procavia capensis	70.14	0.00e+00	1244.00
IUUC-Pva-102335	Pteropus vampyrus	86.21	0.00e+00	2149.00
IUUC-Ptt-103973	Puccinia triticina	25.07	6.00e-27	117.00
IUUC-Rno-106122	Rattus norvegicus	87.14	0.00e+00	2198.00
IUUC-Sha-106851	Sarcophilus harrisii	88.24	0.00e+00	2170.00
IUUC-Sit-110414	Setaria italica	39.76	2.00e-13	71.20
IUUC-Sbi-114170	Sorghum bicolor	39.33	6.00e-14	73.20
IUUC-Sre-115028	Sporisorium reilianum	35.10	2.00e-32	135.00
IUUC-Tgu-117028	Taeniopygia guttata	90.36	0.00e+00	2278.00
IUUC-Tru-117789	Takifugu rubripes	75.90	0.00e+00	1849.00
IUUC-Tsy-119039	Tarsius syrichta	91.89	0.00e+00	1356.00
IUUC-Tni-119952	Tetraodon nigroviridis	72.89	0.00e+00	1717.00
IUUC-Tae-123242	Triticum aestivum	40.96	3.00e-13	70.90
IUUC-Tur-126623	Triticum urartu	39.77	3.00e-13	70.90
IUUC-Tbe-127754	Tupaia belangeri	75.30	0.00e+00	1529.00
IUUC-Ttr-129178	Tursiops truncatus	89.06	0.00e+00	2219.00
IUUC-Uma-129456	Ustilago maydis	31.40	2.00e-31	132.00
IUUC-Vpa-130687	Vicugna pacos	81.07	0.00e+00	1065.00
IUUC-Xtr-132905	Xenopus tropicalis	86.88	0.00e+00	2149.00
IUUC-Xma-134144	Xiphophorus maculatus	75.73	0.00e+00	1839.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence