iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-047872

Ensembl Protein ID

ENSSTOP00000021235.1

UniProt Accession

I3NA38; I3NA38_ICTTR

Genbank Protein ID

ENSSTOP00000021235

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01072723

Gene Name

BTRC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000022481.1	ENSSTOT00000030000.1	ENSSTOP00000021235.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.70e-54	177.1	405	440
UBD/Beta-Prp	7.30e-62	209.2	319	443

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlrtgvll 36
           gH++ v+c++f d +++vsG++Dg+ikvWDl    ++
   Q: 405  GHEELVRCIRF-DnKRIVSGAYDGKIKVWDLVAALDP 440
           8**********.44****************9876665 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           l r l gh a+v+ v+f+++  ++v++s Drtikvw+ st++ v+tl+gh++ + +l++      +vsGs+d+tir+wd+e g cl+ +
   Q: 319  LRRVLVGHRAAVNVVDFDDK--YIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRD--RLVVSGSSDNTIRLWDIECGACLR-V 402
           445569************99..8*************************************9..************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdl........k 167
           l+gh+++v+c++++   + +vsG++D+++++Wdl        +
   Q: 403  LEGHEELVRCIRFDN--KRIVSGAYDGKIKVWDLvaaldpraP 443
           *************99..****************9555555552 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MKTENCVAKT KLANGTSSMI VPKQRKLSAS YEKEKELCVK YFEQWSESDQ VEFVEHLISQ 60
MCHYQHGHIN SYLKPMLQRD FITALPARGL DHIAENILSY LDAKSLCAAE LVCKEWYRVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGTAGGAGA GGGCGGGGGG AAGGAAGAGG AGGCGGGATC CCTGCGCTGC GTTGGCTGCG 60
GCCTGGCACC AAAGGGGCGG CCCCGGCGGA GAGCAGACCC AGTGGCCCTG GCGATTATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR021977--Beta-TrCP_D
IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12125--Beta-TrCP_D
PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM01028--Beta-TrCP_D
SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0071407--P:cellular response to organic cyclic compound
GO:0033598--P:mammary gland epithelial cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0042753--P:positive regulation of circadian rhythm
GO:0045862--P:positive regulation of proteolysis
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006470--P:protein dephosphorylation
GO:0031648--P:protein destabilization
GO:0000209--P:protein polyubiquitination
GO:0060828--P:regulation of canonical Wnt signaling pathway
GO:0051726--P:regulation of cell cycle
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061136--P:regulation of proteasomal protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001961	Ailuropoda melanoleuca	99.56	0.00e+00	941.00
IUUC-Apl-003437	Anas platyrhynchos	98.43	0.00e+00	912.00
IUUC-Aca-004410	Anolis carolinensis	97.79	0.00e+00	926.00
IUUC-Acl-008355	Aspergillus clavatus	30.47	1.00e-48	187.00
IUUC-Afl-008678	Aspergillus flavus	34.42	3.00e-43	169.00
IUUC-Afu-008790	Aspergillus fumigatus	31.30	1.00e-46	181.00
IUUC-Ani-009431	Aspergillus nidulans	35.74	1.00e-44	174.00
IUUC-Ang-009766	Aspergillus niger	32.07	3.00e-50	192.00
IUUC-Aor-010185	Aspergillus oryzae	29.28	1.00e-48	187.00
IUUC-Ate-010492	Aspergillus terreus	31.47	3.00e-48	186.00
IUUC-Ame-011393	Astyanax mexicanus	84.65	0.00e+00	790.00
IUUC-Bgr-012194	Blumeria graminis	32.76	2.00e-50	193.00
IUUC-Bta-013453	Bos taurus	99.56	0.00e+00	941.00
IUUC-Bci-013685	Botrytis cinerea	32.68	7.00e-51	194.00
IUUC-Cel-018392	Caenorhabditis elegans	63.03	2.00e-163	569.00
IUUC-Cja-019121	Callithrix jacchus	99.56	0.00e+00	941.00
IUUC-Cfa-020553	Canis familiaris	99.78	0.00e+00	942.00
IUUC-Cpo-022126	Cavia porcellus	97.57	0.00e+00	886.00
IUUC-Csa-023688	Chlorocebus sabaeus	99.56	0.00e+00	941.00
IUUC-Cho-024658	Choloepus hoffmanni	82.03	2.00e-107	382.00
IUUC-Cin-025188	Ciona intestinalis	81.13	0.00e+00	736.00
IUUC-Csv-026020	Ciona savignyi	78.01	0.00e+00	712.00
IUUC-Cgl-026429	Colletotrichum gloeosporioides	33.83	2.00e-57	216.00
IUUC-Dre-028160	Danio rerio	84.88	0.00e+00	793.00
IUUC-Dno-029484	Dasypus novemcinctus	99.12	0.00e+00	936.00
IUUC-Dor-031010	Dipodomys ordii	97.52	0.00e+00	900.00
IUUC-Dse-031287	Dothistroma septosporum	29.83	1.00e-50	194.00
IUUC-Dme-031885	Drosophila melanogaster	80.91	0.00e+00	747.00
IUUC-Ete-032978	Echinops telfairi	82.53	0.00e+00	738.00
IUUC-Eca-033374	Equus caballus	99.34	0.00e+00	937.00
IUUC-Eeu-034760	Erinaceus europaeus	75.41	0.00e+00	637.00
IUUC-Fca-035427	Felis catus	99.78	0.00e+00	942.00
IUUC-Fal-037530	Ficedula albicollis	98.90	0.00e+00	935.00
IUUC-Fox-037978	Fusarium oxysporum	34.73	3.00e-59	223.00
IUUC-Fso-038077	Fusarium solani	32.75	2.00e-54	206.00
IUUC-Gmo-038590	Gadus morhua	82.42	0.00e+00	781.00
IUUC-Ggr-039974	Gaeumannomyces graminis	33.50	2.00e-53	204.00
IUUC-Gga-041087	Gallus gallus	98.90	0.00e+00	935.00
IUUC-Gac-041305	Gasterosteus aculeatus	84.08	0.00e+00	783.00
IUUC-Ggo-045369	Gorilla gorilla	99.56	0.00e+00	940.00
IUUC-Hsa-045962	Homo sapiens	99.56	0.00e+00	941.00
IUUC-Lch-050285	Latimeria chalumnae	90.13	0.00e+00	841.00
IUUC-Loc-052686	Lepisosteus oculatus	96.91	0.00e+00	919.00
IUUC-Lma-053289	Leptosphaeria maculans	38.43	2.00e-47	184.00
IUUC-Laf-054022	Loxodonta africana	99.78	0.00e+00	940.00
IUUC-Mcc-055782	Macaca mulatta	99.56	0.00e+00	939.00
IUUC-Meu-056078	Macropus eugenii	90.54	0.00e+00	820.00
IUUC-Mor-057283	Magnaporthe oryzae	34.58	5.00e-56	212.00
IUUC-Mpo-057540	Magnaporthe poae	33.75	6.00e-54	205.00
IUUC-Mga-059388	Meleagris gallopavo	98.90	0.00e+00	935.00
IUUC-Mmr-060969	Microcebus murinus	99.78	0.00e+00	942.00
IUUC-Mdo-063041	Monodelphis domestica	99.34	0.00e+00	937.00
IUUC-Mmu-064096	Mus musculus	98.90	0.00e+00	934.00
IUUC-Mpu-066875	Mustela putorius furo	99.78	0.00e+00	941.00
IUUC-Mlu-067621	Myotis lucifugus	99.11	0.00e+00	924.00
IUUC-Nfi-068263	Neosartorya fischeri	30.41	5.00e-48	185.00
IUUC-Ncr-068639	Neurospora crassa	39.93	8.00e-45	175.00
IUUC-Nle-069548	Nomascus leucogenys	99.56	0.00e+00	941.00
IUUC-Opr-071194	Ochotona princeps	92.05	0.00e+00	848.00
IUUC-Ont-071792	Oreochromis niloticus	84.08	0.00e+00	786.00
IUUC-Oan-072867	Ornithorhynchus anatinus	95.33	0.00e+00	925.00
IUUC-Ocu-074246	Oryctolagus cuniculus	99.78	0.00e+00	942.00
IUUC-Ola-086985	Oryzias latipes	84.65	0.00e+00	788.00
IUUC-Oga-088244	Otolemur garnettii	99.55	0.00e+00	924.00
IUUC-Oar-089199	Ovis aries	98.90	0.00e+00	933.00
IUUC-Ptr-091039	Pan troglodytes	88.49	0.00e+00	827.00
IUUC-Pan-092826	Papio anubis	99.56	0.00e+00	941.00
IUUC-Psi-093485	Pelodiscus sinensis	96.47	0.00e+00	902.00
IUUC-Pma-094315	Petromyzon marinus	84.63	0.00e+00	772.00
IUUC-Pno-094808	Phaeosphaeria nodorum	29.58	2.00e-43	170.00
IUUC-Pfo-096783	Poecilia formosa	84.88	0.00e+00	789.00
IUUC-Pab-097680	Pongo abelii	99.12	0.00e+00	936.00
IUUC-Pca-100843	Procavia capensis	91.39	0.00e+00	829.00
IUUC-Pva-102793	Pteropus vampyrus	98.42	0.00e+00	899.00
IUUC-Pgr-103331	Puccinia graminis	39.53	4.00e-50	192.00
IUUC-Ptt-103853	Puccinia triticina	32.26	4.00e-58	218.00
IUUC-Pte-104392	Pyrenophora teres	37.37	4.00e-47	183.00
IUUC-Pyt-104678	Pyrenophora triticirepentis	37.72	2.00e-47	184.00
IUUC-Rno-105304	Rattus norvegicus	98.90	0.00e+00	934.00
IUUC-Sha-107454	Sarcophilus harrisii	99.34	0.00e+00	936.00
IUUC-Spo-108200	Schizosaccharomyces pombe	32.78	9.00e-61	227.00
IUUC-Ssl-108619	Sclerotinia sclerotiorum	36.67	4.00e-42	166.00
IUUC-Sar-113471	Sorex araneus	78.15	0.00e+00	666.00
IUUC-Ssc-115490	Sus scrofa	99.56	0.00e+00	940.00
IUUC-Tgu-117445	Taeniopygia guttata	98.68	0.00e+00	935.00
IUUC-Tru-117671	Takifugu rubripes	81.70	0.00e+00	783.00
IUUC-Tsy-118983	Tarsius syrichta	94.04	0.00e+00	876.00
IUUC-Tni-120359	Tetraodon nigroviridis	81.48	0.00e+00	781.00
IUUC-Tre-122207	Trichoderma reesei	34.49	2.00e-53	203.00
IUUC-Tme-127141	Tuber melanosporum	37.05	6.00e-61	228.00
IUUC-Tbe-128146	Tupaia belangeri	86.98	0.00e+00	752.00
IUUC-Ttr-128946	Tursiops truncatus	99.56	0.00e+00	941.00
IUUC-Uma-129491	Ustilago maydis	38.21	2.00e-44	174.00
IUUC-Vda-129941	Verticillium dahliae	32.84	2.00e-54	207.00
IUUC-Vpa-130709	Vicugna pacos	97.35	0.00e+00	912.00
IUUC-Xtr-132861	Xenopus tropicalis	96.91	0.00e+00	919.00
IUUC-Yli-134582	Yarrowia lipolytica	34.94	4.00e-53	202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence