iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007151

UUCD1 version

UUC-ArT-01406

Ensembl Protein ID

AT4G21100.1

UniProt Accession

O49552; Q0WML4; Q570Q9; DDB1B_ARATH

Genbank Protein ID

CAA17529.1; CAB79110.1; AEE84401.1; BAD95136.1; BAF01636.1

Protein Name

DNA damage-binding protein 1b; UV-damaged DNA-binding protein 1b

Genbank Nucleotide ID

AL021960; AL161554; CP002687; AK220648; AK229805

Gene Name

DDB1B; At4g21100; F7J7.40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G21100	AT4G21100.1	AT4G21100.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	HINT	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/DCX/DDB1	DDB1	18223036; 20622147

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DDB1	0	1705.3	736	1088

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DDB1

   S: 784  seleenevnfllvlDkntfelllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgrilvfsvedslklkLltvaekkvkgavidl 879
            ++ee+e++f+++lD+++fe+l++++l+++E+++s+lS++++dD+++yy+v+ta+vlpeene++kgrilvf+ve++   +L+ ++ek++kgav++l
   Q: 736  PSAEESESHFVRLLDAQSFEFLSSYPLDAFECGCSILSCSFTDDKNVYYCVGTAYVLPEENEPTKGRILVFIVEEG---RLQLITEKETKGAVYSL 828
           5789************************************************************************...***************** PP
   S: 880  vklNgkllaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmrsvtLllykdlegsfeEsardynlewmsaveilnddif 975
           +++Ngklla+in++i+ly+w++++++++el++eC+++++ilaL+++tr+dfi+VgDlm+s++Ll+yk++eg++eE+ardyn++wm+aveilnddi+
   Q: 829  NAFNGKLLASINQKIQLYKWMLRDDGTRELQSECGHHGHILALYVQTRGDFIAVGDLMKSISLLIYKHEEGAIEERARDYNANWMTAVEILNDDIY 924
           ************************************************************************************************ PP
   S: 976  lgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvlqdvgerevnrssevifgtengeigvilrlrrellkflrnlestlkk 1071
           lg++nc+N+f+vkk+ ++g+tdeer+++e+vge+++gefv++fr+g+lv++ + +++++++++vifgt++g+igvi++l++e+++fl++l+++l+k
   Q: 925  LGTDNCFNIFTVKKN-NEGATDEERARMEVVGEYHIGEFVNRFRHGSLVMKLP-DSDIGQIPTVIFGTVSGMIGVIASLPQEQYAFLEKLQTSLRK 1018
           ***************.***********************************98.****************************************** PP
   S: 1072 vikrvakieHssyRsFetekrterasgfvdgdLiesilDlsrdkavdilkvlyekrwnskkevsveeivKlveelkrlh 1150
           vik+v++++H+++RsF++ekrt++a+g++dgdLies+lDlsr k+++i+k++         +v+vee++K+veel+rlh
   Q: 1019 VIKGVGGLSHEQWRSFNNEKRTAEAKGYLDGDLIESFLDLSRGKMEEISKGM---------DVQVEELCKRVEELTRLH 1088
           ****************************************************.........9***************98 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness (By similarity). Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB) (By similarity).

Protein Sequence
(Fasta)

MSVWNYAVTA QKPTCVTHSC VGNFTSPQEL NLIVAKSTRI EIHLLSPQGL QTILDVPLYG 60
RIATMELFRP HGEAQDFLFV ATERYKFCVL QWDYESSELI TRAMGDVSDR IGRPTDNGQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGCCGGGC CGAATTAGAT CCAGGGTAAA CCTATTAATT CCAGTTATAT ACCAAACCGG 60
AACGTACCGT CTTTAAAATT TCAATTTTGT GTTCTGAACC GGCCGTTCTT CTTAACCTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0238--DNA-binding
KW-0539--Nucleus
KW-0607--Phytochrome signaling pathway
KW-1185--Reference proteome

Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom

Pfam

PF03178--CPSF_A

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0009793--P:embryo development ending in seed dormancy
GO:0006289--P:nucleotide-excision repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0009585--P:red, far-red light phototransduction

KEGG

ath:AT4G21100

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005782	Arabidopsis lyrata	97.61	0.00e+00	2176.00
IUUC-Bgr-012164	Blumeria graminis	28.96	2.00e-119	423.00
IUUC-Cel-018239	Caenorhabditis elegans	34.10	1.00e-178	620.00
IUUC-Ete-032913	Echinops telfairi	54.90	3.00e-81	296.00
IUUC-Fso-038292	Fusarium solani	27.93	7.00e-119	421.00
IUUC-Ggr-039907	Gaeumannomyces graminis	27.23	2.00e-113	403.00
IUUC-Mpo-057562	Magnaporthe poae	26.84	7.00e-108	384.00
IUUC-Spo-108029	Schizosaccharomyces pombe	27.31	6.00e-119	421.00
IUUC-Tvi-122512	Trichoderma virens	28.32	2.00e-123	436.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence