iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023609

Ensembl Protein ID

ENSCSAP00000000639.1

UniProt Accession

A0A0D9QWA0; A0A0D9QWA0_CHLSB

Genbank Protein ID

ENSCSAP00000000639

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01134247

Gene Name

TRIM5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000004290.1	ENSCSAT00000002319.1	ENSCSAP00000000639.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-09	36.9	15	60
E3 activity/RING/U-box	3.50e-07	30.2	9	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl..qkwpglknssskefrCPlCr 46
           C+iCle + + pl+lpCgH f++ C+  ++   ++  +  e +CP+Cr
   Q: 15   CPICLELLTE-PLSLPCGHSFCQACItaNHK-ESMLYKEEERSCPVCR 60
           ********99.***************76444.66666888889****8 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk........tcPvtrqplteedlvPnltlrrliqa 67
           v ee  CpI lel ++P  lp+G+++ +++I      +++        +cPv+r + ++e++ Pn  + +++++
   Q: 9    VKEEVTCPICLELLTEPLSLPCGHSFCQACITANH--KESmlykeeerSCPVCRISYQPENIQPNRHVANIVEK 80
           78999**************************8744..22234566667*****************998887776 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MASGILLNVK EEVTCPICLE LLTEPLSLPC GHSFCQACIT ANHKESMLYK EEERSCPVCR 60
ISYQPENIQP NRHVANIVEK LREVKLSPEE GQKVDHCARH GEKLLLFCQE DSKVICWLCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCACTTTC CTGCCCCGAT GTGAGCAAGA ATTTCCTGCA CTTCCTCTAG GAAAATTCCT 60
TTGCGCAAAT CAGTCCCCTG GATTGGTGAG TGAATCCTAA CCATGTCTTT CCTGGCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR032917--TRIM5
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:1990462--C:omegasome
GO:0000932--C:P-body
GO:0008329--F:signaling pattern recognition receptor activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0051607--P:defense response to virus
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410--P:positive regulation of MAPK cascade
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0031664--P:regulation of lipopolysaccharide-mediated signaling pathway
GO:0032880--P:regulation of protein localization

KEGG

csab:103247881

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bta-013110	Bos taurus	55.89	7.00e-156	543.00
IUUC-Cja-019944	Callithrix jacchus	66.60	0.00e+00	655.00
IUUC-Cre-022597	Chlamydomonas reinhardtii	31.71	9.00e-09	54.70
IUUC-Cho-024416	Choloepus hoffmanni	62.65	2.00e-92	333.00
IUUC-Dor-030700	Dipodomys ordii	49.81	1.00e-140	493.00
IUUC-Ete-033021	Echinops telfairi	51.17	3.00e-121	428.00
IUUC-Ggo-044783	Gorilla gorilla	81.17	0.00e+00	807.00
IUUC-Hsa-046573	Homo sapiens	83.88	0.00e+00	852.00
IUUC-Kpa-049392	Komagataella pastoris	33.04	7.00e-10	57.80
IUUC-Mcc-055525	Macaca mulatta	93.01	0.00e+00	992.00
IUUC-Mmr-061336	Microcebus murinus	59.46	1.00e-151	529.00
IUUC-Mlu-067695	Myotis lucifugus	57.52	2.00e-152	531.00
IUUC-Nle-069081	Nomascus leucogenys	79.42	0.00e+00	805.00
IUUC-Opr-071057	Ochotona princeps	50.98	1.00e-133	469.00
IUUC-Oar-090073	Ovis aries	55.01	1.00e-144	506.00
IUUC-Ptr-090927	Pan troglodytes	82.72	0.00e+00	828.00
IUUC-Pan-092730	Papio anubis	92.43	0.00e+00	985.00
IUUC-Pab-098782	Pongo abelii	82.72	0.00e+00	845.00
IUUC-Sar-113094	Sorex araneus	47.96	2.00e-114	406.00
IUUC-Tsy-119055	Tarsius syrichta	60.27	2.00e-166	578.00
IUUC-Tbe-127426	Tupaia belangeri	51.16	1.00e-131	462.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence