iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052621

Ensembl Protein ID

ENSLOCP00000010257.1

UniProt Accession

W5MPE8; W5MPE8_LEPOC

Genbank Protein ID

ENSLOCP00000010257

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01013695

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000008435.1	ENSLOCT00000010270.1	ENSLOCP00000010257.1
ENSLOCG00000008435.1	ENSLOCT00000010285.1	ENSLOCP00000010272.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-84	284.2	119	417

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl+NlgNtC++NS+LQcL+ + +l++++l+++++k+      ep  ++++++q+ ++++  ++ ++++p  +l+ lk++a++f+  +q+
   Q: 119  GLQNLGNTCFLNSALQCLTYTAPLANYMLSREHSKTC----HEPGFCMMCTMQNHITQVFANSGNVIKPIGVLNELKRIAKHFRFGSQE 203
           9*****************************5554444....36899******************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl++ +d++++++          + ++         + + +++ ++l++++F+g l+s++kcl+c+ vs +++p ld+ l+++  
   Q: 204  DAHEFLRYTVDAMQKSC----------LPGS---------KLDRQTQATTLVHQIFGGYLRSRVKCLNCKAVSDTFDPYLDVALEIKTA 273
           *****************..........3333.........356789999**************************************** PP
   S: 180  eetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctsp 268
           +     +++++Le+f+k+e+l+gen+y+c+kckk + a+k++++++ ++vL++ LkRf    ++++  ki k v +p+ Ld++pf++++
   Q: 274  Q-----NISKALEQFVKPEHLDGENAYKCTKCKKMVPASKRFTIHRGSNVLTISLKRF----ANYNGGKIAKDVRYPEYLDIRPFMSQS 353
           *.....9***************************************************....557788********************6 PP
   S: 269  eekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
             +   ++ Y L+av+vHsG s++ GHY++yvk ++g+W++++Ds+V+ ++  +vl+   ++aYvlfY r
   Q: 354  HGE---PQVYVLYAVLVHSGfSCHAGHYYCYVKASNGQWYQMNDSSVSISDIRSVLN---QQAYVLFYIR 417
           554...9**************************************************...********87 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MTIVDKPTET SDPESGQSEL SGSPTPSSSG DMDTSSASWG AGSSTSDPPK NKTPCVGPTP 60
GAAVYTSSSV PAPERPKSPI HKEQSLMASG DGIALPQKIL FPAERLSLKW NQVHRIGAGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACTTGCACT CTTCATGTTC GTAGGCCAGG TGAAGAGTTT TTTTAACATA GTCTCCTAAT 60
CCCGCGCCTT CCTTTACTGC TCATAAGGTG GAAATACAAT GTTCCTTAAA CTCCCATCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001055	Aegilops tauschii	42.31	2.00e-69	257.00
IUUC-Atr-003102	Amborella trichopoda	48.38	2.00e-88	320.00
IUUC-Apl-003459	Anas platyrhynchos	53.63	4.00e-152	532.00
IUUC-Aca-004440	Anolis carolinensis	59.44	0.00e+00	741.00
IUUC-Aly-006389	Arabidopsis lyrata	44.77	2.00e-79	290.00
IUUC-Ath-006710	Arabidopsis thaliana	44.44	3.00e-79	289.00
IUUC-Ago-007836	Ashbya gossypii	26.94	3.00e-31	130.00
IUUC-Ame-011358	Astyanax mexicanus	73.71	0.00e+00	815.00
IUUC-Bta-012803	Bos taurus	65.67	0.00e+00	701.00
IUUC-Bol-015086	Brassica oleracea	44.48	4.00e-84	306.00
IUUC-Bra-016634	Brassica rapa	44.59	2.00e-84	307.00
IUUC-Cja-019199	Callithrix jacchus	64.34	0.00e+00	699.00
IUUC-Cfa-020597	Canis familiaris	65.56	0.00e+00	699.00
IUUC-Cpo-021945	Cavia porcellus	64.51	0.00e+00	706.00
IUUC-Csa-023485	Chlorocebus sabaeus	64.69	0.00e+00	702.00
IUUC-Cho-024575	Choloepus hoffmanni	61.39	5.00e-149	522.00
IUUC-Dre-028442	Danio rerio	70.85	0.00e+00	790.00
IUUC-Dno-029673	Dasypus novemcinctus	64.75	0.00e+00	697.00
IUUC-Ete-033088	Echinops telfairi	73.78	4.00e-154	538.00
IUUC-Eca-033579	Equus caballus	65.38	0.00e+00	707.00
IUUC-Eeu-034511	Erinaceus europaeus	42.75	2.00e-84	307.00
IUUC-Fca-035792	Felis catus	65.08	0.00e+00	688.00
IUUC-Fal-037075	Ficedula albicollis	56.81	1.00e-168	587.00
IUUC-Gmo-038478	Gadus morhua	74.03	7.00e-172	596.00
IUUC-Gga-040504	Gallus gallus	56.43	1.00e-164	573.00
IUUC-Gma-044075	Glycine max	50.16	1.00e-87	317.00
IUUC-Ggo-044798	Gorilla gorilla	62.94	5.00e-175	608.00
IUUC-Hsa-046072	Homo sapiens	64.86	0.00e+00	699.00
IUUC-Hvu-047620	Hordeum vulgare	40.53	1.00e-71	265.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	50.32	0.00e+00	723.00
IUUC-Lch-049867	Latimeria chalumnae	60.32	0.00e+00	809.00
IUUC-Laf-054330	Loxodonta africana	64.34	0.00e+00	701.00
IUUC-Mtr-058537	Medicago truncatula	46.51	1.00e-87	317.00
IUUC-Mla-059049	Melampsora laricipopulina	40.62	2.00e-60	226.00
IUUC-Mga-059501	Meleagris gallopavo	51.26	1.00e-146	514.00
IUUC-Mvi-060547	Microbotryum violaceum	44.29	2.00e-80	293.00
IUUC-Mmr-060864	Microcebus murinus	54.73	0.00e+00	721.00
IUUC-Mdo-062395	Monodelphis domestica	66.84	0.00e+00	752.00
IUUC-Mmu-064236	Mus musculus	64.32	0.00e+00	683.00
IUUC-Mac-064815	Musa acuminata	48.53	1.00e-87	317.00
IUUC-Mpu-065822	Mustela putorius furo	65.73	0.00e+00	717.00
IUUC-Mlu-067091	Myotis lucifugus	63.64	0.00e+00	691.00
IUUC-Nle-069004	Nomascus leucogenys	64.69	0.00e+00	702.00
IUUC-Opr-071170	Ochotona princeps	67.26	5.00e-155	542.00
IUUC-Ont-071832	Oreochromis niloticus	68.51	0.00e+00	757.00
IUUC-Oan-073711	Ornithorhynchus anatinus	71.98	0.00e+00	699.00
IUUC-Ocu-074596	Oryctolagus cuniculus	65.57	0.00e+00	688.00
IUUC-Oga-088641	Otolemur garnettii	64.67	0.00e+00	698.00
IUUC-Oar-089760	Ovis aries	72.49	0.00e+00	667.00
IUUC-Ptr-091445	Pan troglodytes	64.69	0.00e+00	700.00
IUUC-Pan-092484	Papio anubis	64.69	0.00e+00	702.00
IUUC-Psi-093277	Pelodiscus sinensis	66.26	0.00e+00	723.00
IUUC-Pma-094651	Petromyzon marinus	40.55	3.00e-52	198.00
IUUC-Pfo-096469	Poecilia formosa	68.58	0.00e+00	739.00
IUUC-Pab-097794	Pongo abelii	68.12	0.00e+00	686.00
IUUC-Pva-103238	Pteropus vampyrus	59.44	1.00e-178	620.00
IUUC-Rno-105068	Rattus norvegicus	66.48	0.00e+00	690.00
IUUC-Sha-106713	Sarcophilus harrisii	67.19	0.00e+00	770.00
IUUC-Smo-108763	Selaginella moellendorffii	49.35	3.00e-83	301.00
IUUC-Sly-111722	Solanum lycopersicum	46.23	1.00e-82	301.00
IUUC-Stu-112912	Solanum tuberosum	43.68	3.00e-82	300.00
IUUC-Sar-113340	Sorex araneus	71.55	0.00e+00	650.00
IUUC-Tgu-117149	Taeniopygia guttata	57.28	8.00e-170	591.00
IUUC-Tru-117776	Takifugu rubripes	71.23	0.00e+00	716.00
IUUC-Tsy-118974	Tarsius syrichta	64.16	0.00e+00	700.00
IUUC-Tni-120774	Tetraodon nigroviridis	75.38	0.00e+00	691.00
IUUC-Ttr-128764	Tursiops truncatus	57.89	6.00e-162	565.00
IUUC-Vvi-131535	Vitis vinifera	48.25	1.00e-90	327.00
IUUC-Xtr-132544	Xenopus tropicalis	70.71	1.00e-157	549.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence