iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-054844

Ensembl Protein ID

ENSMMUP00000023598.1

UniProt Accession

F7ELX5; F7ELX5_MACMU

Genbank Protein ID

AFE66911.1; AFH28889.1

Protein Name

CD2-associated protein

Genbank Nucleotide ID

JSUE03030979; JU472085

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017952.2	ENSMMUT00000025223.2	ENSMMUP00000023598.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.30e-67	222.8	270	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deLt+k+G+++++i+ke+ ++gW+kg  el+gk+G+fP+nF ++++
   Q: 270  AKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWKG--ELNGKEGVFPDNFAVQIN 329
           689***************************************..9**************997 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE 60
TEFKDDSLPI KRERHGNVAS LVQRISTYGL PAGGIQPHPQ TKNIKKKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGTAAGA GACTCGGGCG CTTCCAGTCG CCCGTCCGGA CCTTCCAGAT CCGGGGAGGC 60
TGTGCCCTTT CTCGGCCTTA TGGGGAGGCA ACGGCGGTCA GCCCCTGAGC GGCAGCATCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

KEGG

mcc:705221

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	88.92	0.00e+00	966.00
IUUC-Apl-003573	Anas platyrhynchos	63.82	6.00e-165	574.00
IUUC-Aca-005118	Anolis carolinensis	64.58	9.00e-168	583.00
IUUC-Ame-010657	Astyanax mexicanus	53.93	2.00e-91	330.00
IUUC-Bta-012577	Bos taurus	86.31	0.00e+00	876.00
IUUC-Cja-020010	Callithrix jacchus	93.27	0.00e+00	998.00
IUUC-Cfa-020040	Canis familiaris	91.38	0.00e+00	963.00
IUUC-Cpo-021906	Cavia porcellus	83.39	0.00e+00	817.00
IUUC-Csa-024008	Chlorocebus sabaeus	99.53	0.00e+00	1005.00
IUUC-Cho-024359	Choloepus hoffmanni	72.02	2.00e-59	223.00
IUUC-Csv-026228	Ciona savignyi	40.37	2.00e-24	104.00
IUUC-Dre-027661	Danio rerio	54.78	1.00e-93	337.00
IUUC-Dno-029568	Dasypus novemcinctus	87.52	0.00e+00	879.00
IUUC-Dor-030286	Dipodomys ordii	76.96	0.00e+00	716.00
IUUC-Ete-032576	Echinops telfairi	68.24	0.00e+00	635.00
IUUC-Eca-033438	Equus caballus	89.98	0.00e+00	980.00
IUUC-Eeu-034588	Erinaceus europaeus	73.01	2.00e-150	525.00
IUUC-Fca-036597	Felis catus	90.02	0.00e+00	982.00
IUUC-Fal-037305	Ficedula albicollis	64.22	2.00e-170	592.00
IUUC-Gmo-039516	Gadus morhua	46.04	5.00e-67	249.00
IUUC-Gga-040979	Gallus gallus	66.00	0.00e+00	630.00
IUUC-Gac-041945	Gasterosteus aculeatus	52.89	3.00e-80	293.00
IUUC-Ggo-044488	Gorilla gorilla	96.40	0.00e+00	1009.00
IUUC-Hsa-045909	Homo sapiens	96.24	0.00e+00	1009.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	91.52	5.00e-125	440.00
IUUC-Lch-049481	Latimeria chalumnae	55.32	2.00e-155	543.00
IUUC-Loc-052715	Lepisosteus oculatus	52.04	3.00e-143	502.00
IUUC-Laf-053444	Loxodonta africana	86.43	0.00e+00	917.00
IUUC-Meu-056491	Macropus eugenii	65.28	0.00e+00	627.00
IUUC-Mga-060154	Meleagris gallopavo	66.20	2.00e-180	625.00
IUUC-Mmr-061099	Microcebus murinus	90.92	0.00e+00	929.00
IUUC-Mdo-062769	Monodelphis domestica	70.57	0.00e+00	758.00
IUUC-Mmu-063136	Mus musculus	85.45	0.00e+00	801.00
IUUC-Mpu-066509	Mustela putorius furo	90.03	0.00e+00	891.00
IUUC-Mlu-067174	Myotis lucifugus	86.43	0.00e+00	892.00
IUUC-Nle-070147	Nomascus leucogenys	96.56	0.00e+00	1018.00
IUUC-Opr-070752	Ochotona princeps	82.97	8.00e-171	593.00
IUUC-Ont-071810	Oreochromis niloticus	56.27	8.00e-102	364.00
IUUC-Oan-072731	Ornithorhynchus anatinus	74.26	6.00e-170	590.00
IUUC-Ocu-074331	Oryctolagus cuniculus	90.50	0.00e+00	917.00
IUUC-Ola-086404	Oryzias latipes	46.71	1.00e-91	330.00
IUUC-Oga-088200	Otolemur garnettii	91.24	0.00e+00	1014.00
IUUC-Oar-090423	Ovis aries	84.60	0.00e+00	842.00
IUUC-Ptr-091230	Pan troglodytes	96.71	0.00e+00	1014.00
IUUC-Pan-091823	Papio anubis	99.53	0.00e+00	1003.00
IUUC-Psi-093127	Pelodiscus sinensis	63.08	1.00e-165	576.00
IUUC-Pfo-096539	Poecilia formosa	50.44	4.00e-89	322.00
IUUC-Pab-097666	Pongo abelii	96.87	0.00e+00	1004.00
IUUC-Pca-100812	Procavia capensis	81.59	2.00e-132	466.00
IUUC-Pva-102260	Pteropus vampyrus	82.88	0.00e+00	773.00
IUUC-Rno-106038	Rattus norvegicus	85.13	0.00e+00	834.00
IUUC-Sha-106975	Sarcophilus harrisii	72.42	0.00e+00	731.00
IUUC-Sar-113386	Sorex araneus	87.40	6.00e-109	388.00
IUUC-Ssc-115569	Sus scrofa	92.31	1.00e-115	408.00
IUUC-Tgu-117104	Taeniopygia guttata	65.03	0.00e+00	632.00
IUUC-Tru-117649	Takifugu rubripes	53.98	4.00e-97	348.00
IUUC-Tsy-119258	Tarsius syrichta	83.07	0.00e+00	852.00
IUUC-Tni-120755	Tetraodon nigroviridis	46.28	6.00e-126	444.00
IUUC-Tbe-127842	Tupaia belangeri	71.59	7.00e-125	441.00
IUUC-Ttr-129205	Tursiops truncatus	89.73	0.00e+00	820.00
IUUC-Vpa-130434	Vicugna pacos	85.79	0.00e+00	775.00
IUUC-Xtr-132766	Xenopus tropicalis	58.11	1.00e-88	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence