iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044498

UUCD1 version

UUC-GoG-00417

Ensembl Protein ID

ENSGGOP00000010066.2

UniProt Accession

G3R475; G3R475_GORGO

Protein Name

Uncharacterized protein

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010317.2	ENSGGOT00000010358.2	ENSGGOP00000010066.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/ZnF_A20	5.60e-19	68.2	13	47

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/ZnF_A20

   S: 1    dpskllCkkgCgfYGnpetngyCSkCyreelrrrr 35
           d+s+llCkkgCg+YGnp+++g+CSkC+ree++++r
   Q: 13   DQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKAR 47
           79*******************************86 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER 60
LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKAEIQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCCTTA AGTCTGAACG CCGAGGAATT CATGTGGATC AATCGGATCT CCTGTGCAAG 60
AAAGGATGTG GTTACTACGG CAACCCTGCC TGGCAGGGTT TCTGCTCCAA GTGCTGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003123--VPS9
IPR002653--Znf_A20

PROSITE

PS51205--VPS9
PS51036--ZF_A20

Pfam

PF02204--VPS9
PF01754--zf-A20

SMART

SM00167--VPS9
SM00259--ZnF_A20

Gene Ontology

GO:0031982--C:vesicle
GO:0003677--F:DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001771	Ailuropoda melanoleuca	72.17	2.00e-173	602.00
IUUC-Apl-004018	Anas platyrhynchos	79.72	0.00e+00	702.00
IUUC-Aca-004889	Anolis carolinensis	31.91	1.00e-08	54.70
IUUC-Ago-007776	Ashbya gossypii	35.88	4.00e-19	89.00
IUUC-Acl-008235	Aspergillus clavatus	41.61	3.00e-26	113.00
IUUC-Afl-008570	Aspergillus flavus	42.29	2.00e-28	120.00
IUUC-Afu-008815	Aspergillus fumigatus	40.00	2.00e-26	114.00
IUUC-Ani-009381	Aspergillus nidulans	40.99	3.00e-26	113.00
IUUC-Ang-009615	Aspergillus niger	40.48	1.00e-27	117.00
IUUC-Aor-010195	Aspergillus oryzae	41.81	9.00e-29	121.00
IUUC-Ate-010514	Aspergillus terreus	42.86	1.00e-27	118.00
IUUC-Ame-011365	Astyanax mexicanus	57.48	4.00e-159	554.00
IUUC-Bta-013124	Bos taurus	83.33	0.00e+00	728.00
IUUC-Bci-013943	Botrytis cinerea	42.57	3.00e-27	117.00
IUUC-Cel-018199	Caenorhabditis elegans	42.95	6.00e-35	142.00
IUUC-Cja-019941	Callithrix jacchus	85.37	0.00e+00	745.00
IUUC-Cfa-020845	Canis familiaris	82.61	0.00e+00	660.00
IUUC-Cpo-022037	Cavia porcellus	82.32	0.00e+00	717.00
IUUC-Csa-023495	Chlorocebus sabaeus	85.37	0.00e+00	750.00
IUUC-Cho-025076	Choloepus hoffmanni	76.63	0.00e+00	639.00
IUUC-Cin-025400	Ciona intestinalis	38.61	3.00e-91	328.00
IUUC-Csv-025941	Ciona savignyi	32.73	8.00e-63	234.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	42.74	2.00e-24	107.00
IUUC-Dre-028484	Danio rerio	62.45	1.00e-160	559.00
IUUC-Dno-028906	Dasypus novemcinctus	83.13	0.00e+00	721.00
IUUC-Dor-030124	Dipodomys ordii	80.65	0.00e+00	688.00
IUUC-Dme-031696	Drosophila melanogaster	29.34	2.00e-56	213.00
IUUC-Ete-032573	Echinops telfairi	74.40	7.00e-162	563.00
IUUC-Eca-033711	Equus caballus	83.54	0.00e+00	730.00
IUUC-Eeu-034459	Erinaceus europaeus	96.97	2.00e-73	270.00
IUUC-Fca-035447	Felis catus	81.71	0.00e+00	735.00
IUUC-Fal-036605	Ficedula albicollis	76.80	0.00e+00	647.00
IUUC-Fox-037967	Fusarium oxysporum	48.68	4.00e-17	83.60
IUUC-Fso-038110	Fusarium solani	39.19	5.00e-25	109.00
IUUC-Gmo-038785	Gadus morhua	57.56	7.00e-163	566.00
IUUC-Ggr-039760	Gaeumannomyces graminis	42.03	1.00e-25	112.00
IUUC-Gga-040584	Gallus gallus	80.28	0.00e+00	712.00
IUUC-Gac-042469	Gasterosteus aculeatus	54.73	1.00e-131	463.00
IUUC-Hsa-046625	Homo sapiens	85.77	0.00e+00	748.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	82.52	0.00e+00	719.00
IUUC-Lch-050529	Latimeria chalumnae	68.41	0.00e+00	723.00
IUUC-Loc-052644	Lepisosteus oculatus	62.41	1.00e-159	556.00
IUUC-Laf-054337	Loxodonta africana	80.49	0.00e+00	707.00
IUUC-Mcc-055659	Macaca mulatta	79.67	9.00e-135	473.00
IUUC-Meu-056084	Macropus eugenii	76.02	1.00e-94	340.00
IUUC-Mpo-057454	Magnaporthe poae	40.40	2.00e-26	114.00
IUUC-Mla-059068	Melampsora laricipopulina	40.14	2.00e-25	110.00
IUUC-Mga-059624	Meleagris gallopavo	69.03	0.00e+00	695.00
IUUC-Mvi-060282	Microbotryum violaceum	49.11	5.00e-21	97.10
IUUC-Mmr-061142	Microcebus murinus	83.33	0.00e+00	734.00
IUUC-Mdo-062289	Monodelphis domestica	79.67	0.00e+00	747.00
IUUC-Mmu-063961	Mus musculus	82.72	0.00e+00	724.00
IUUC-Mpu-066291	Mustela putorius furo	82.93	0.00e+00	730.00
IUUC-Mlu-067431	Myotis lucifugus	79.67	0.00e+00	691.00
IUUC-Nfi-068422	Neosartorya fischeri	40.00	4.00e-27	116.00
IUUC-Ncr-068843	Neurospora crassa	39.60	2.00e-25	110.00
IUUC-Nle-069079	Nomascus leucogenys	85.16	0.00e+00	742.00
IUUC-Opr-070790	Ochotona princeps	94.44	2.00e-57	216.00
IUUC-Ont-071789	Oreochromis niloticus	59.58	4.00e-144	504.00
IUUC-Oan-072946	Ornithorhynchus anatinus	78.30	0.00e+00	674.00
IUUC-Ocu-073816	Oryctolagus cuniculus	83.94	0.00e+00	735.00
IUUC-Ola-086334	Oryzias latipes	53.66	6.00e-138	484.00
IUUC-Olu-087719	Ostreococcus lucimarinus	37.50	8.00e-22	98.20
IUUC-Oga-088992	Otolemur garnettii	73.51	0.00e+00	739.00
IUUC-Oar-089789	Ovis aries	83.57	0.00e+00	732.00
IUUC-Ptr-091636	Pan troglodytes	85.77	0.00e+00	747.00
IUUC-Pan-092911	Papio anubis	84.96	0.00e+00	742.00
IUUC-Psi-093194	Pelodiscus sinensis	69.04	0.00e+00	703.00
IUUC-Pma-094212	Petromyzon marinus	40.32	3.00e-80	292.00
IUUC-Pno-094831	Phaeosphaeria nodorum	40.79	1.00e-24	108.00
IUUC-Pfo-096694	Poecilia formosa	56.39	4.00e-145	508.00
IUUC-Pab-097706	Pongo abelii	85.57	0.00e+00	745.00
IUUC-Pca-100879	Procavia capensis	62.15	4.00e-44	171.00
IUUC-Pva-103225	Pteropus vampyrus	76.41	0.00e+00	649.00
IUUC-Pgr-103564	Puccinia graminis	39.57	3.00e-24	107.00
IUUC-Ptt-103802	Puccinia triticina	45.61	1.00e-24	108.00
IUUC-Rno-106101	Rattus norvegicus	82.52	0.00e+00	723.00
IUUC-Sce-106460	Saccharomyces cerevisiae	36.99	9.00e-21	94.70
IUUC-Sha-106919	Sarcophilus harrisii	70.85	0.00e+00	709.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	37.27	1.00e-24	107.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	29.82	1.00e-07	51.60
IUUC-Sar-112929	Sorex araneus	92.05	5.00e-146	511.00
IUUC-Ssc-115239	Sus scrofa	83.94	0.00e+00	736.00
IUUC-Tgu-117499	Taeniopygia guttata	78.25	0.00e+00	684.00
IUUC-Tru-118027	Takifugu rubripes	52.62	2.00e-110	392.00
IUUC-Tsy-119462	Tarsius syrichta	82.81	0.00e+00	704.00
IUUC-Tni-120855	Tetraodon nigroviridis	52.38	6.00e-141	494.00
IUUC-Tre-122186	Trichoderma reesei	37.87	2.00e-26	114.00
IUUC-Tvi-122541	Trichoderma virens	33.50	3.00e-26	113.00
IUUC-Tbe-127453	Tupaia belangeri	79.53	7.00e-179	620.00
IUUC-Ttr-128526	Tursiops truncatus	83.13	0.00e+00	726.00
IUUC-Vda-129737	Verticillium dahliae	38.36	1.00e-21	98.60
IUUC-Vpa-130505	Vicugna pacos	73.58	3.00e-161	561.00
IUUC-Vvi-131088	Vitis vinifera	43.52	3.00e-20	93.20
IUUC-Xtr-132799	Xenopus tropicalis	65.45	6.00e-176	610.00
IUUC-Xma-133345	Xiphophorus maculatus	56.45	5.00e-140	491.00
IUUC-Yli-134416	Yarrowia lipolytica	47.46	1.00e-25	110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence