iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069535

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01033571

Gene Name

SH3RF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000009812.1	ENSNLET00000012532.1	ENSNLEP00000011949.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.30e-08	33.3	12	53
UBD/SH3	1.40e-30	105.0	383	437

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+e ++   +vlpC+H+f++ Clq++     ++ ke rCP Cr
   Q: 12   CPVCFEKLDVTAKVLPCQHTFCKPCLQRV----FKAHKELRCPECR 53
           ********88899****************....99**********8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + + +l++y+a   deL l+kG+ ++v+  ++qd gWl+gv+  +g+ G+fP+n+v 
   Q: 383  NMFVALHSYSARGPDELDLQKGEGIRVL-GKCQD-GWLRGVSLVTGRVGIFPNNYVI 437
           7889************************.77776.9*******************96 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MDDLTLLDLL ECPVCFEKLD VTAKVLPCQH TFCKPCLQRV FKAHKELRCP ECRTPVFSNI 60
EALPANLLLV RLLDGVRSGQ SSGRGGSFRR PGTMTLQDGR KSRTNPRRLQ ASPFRLVPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGATT TGACATTACT TGATCTTCTG GAGTGCCCTG TGTGCTTTGA GAAGCTCGAT 60
GTCACAGCCA AAGTCCTCCC TTGCCAGCAC ACCTTCTGCA AACCATGTCT ACAGCGGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011511--SH3_2
IPR001452--SH3_domain
IPR028511--SH3RF2
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9
PF13445--zf-RING_UBOX

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0010923--P:negative regulation of phosphatase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001594	Ailuropoda melanoleuca	86.28	0.00e+00	1075.00
IUUC-Apl-003443	Anas platyrhynchos	58.44	1.00e-162	566.00
IUUC-Aca-004632	Anolis carolinensis	51.89	2.00e-167	582.00
IUUC-Bta-013400	Bos taurus	87.04	0.00e+00	1045.00
IUUC-Cel-018180	Caenorhabditis elegans	26.94	2.00e-20	95.10
IUUC-Cja-019686	Callithrix jacchus	82.34	0.00e+00	1036.00
IUUC-Cfa-020893	Canis familiaris	88.24	0.00e+00	1090.00
IUUC-Cpo-021638	Cavia porcellus	82.37	0.00e+00	1033.00
IUUC-Csa-023846	Chlorocebus sabaeus	94.58	0.00e+00	1189.00
IUUC-Cho-024609	Choloepus hoffmanni	86.32	2.00e-163	569.00
IUUC-Dno-028940	Dasypus novemcinctus	84.71	0.00e+00	1044.00
IUUC-Dor-030491	Dipodomys ordii	77.39	6.00e-128	451.00
IUUC-Dse-031414	Dothistroma septosporum	35.82	1.00e-08	55.50
IUUC-Ete-032513	Echinops telfairi	84.01	0.00e+00	1027.00
IUUC-Eca-034241	Equus caballus	89.06	0.00e+00	1119.00
IUUC-Eeu-034636	Erinaceus europaeus	79.78	0.00e+00	903.00
IUUC-Fca-035862	Felis catus	85.36	0.00e+00	1058.00
IUUC-Gga-040748	Gallus gallus	54.18	5.00e-140	491.00
IUUC-Ggo-045267	Gorilla gorilla	95.83	0.00e+00	1234.00
IUUC-Hsa-045761	Homo sapiens	95.27	0.00e+00	1225.00
IUUC-Itr-048226	Ictidomys tridecemlineatus	83.80	0.00e+00	1046.00
IUUC-Lch-050498	Latimeria chalumnae	43.74	1.00e-119	424.00
IUUC-Laf-054061	Loxodonta africana	77.72	0.00e+00	810.00
IUUC-Mcc-054746	Macaca mulatta	93.79	0.00e+00	1162.00
IUUC-Meu-056390	Macropus eugenii	57.98	4.00e-88	319.00
IUUC-Mga-059398	Meleagris gallopavo	64.77	1.00e-88	319.00
IUUC-Mmr-061390	Microcebus murinus	85.90	0.00e+00	907.00
IUUC-Mdo-062951	Monodelphis domestica	71.47	0.00e+00	936.00
IUUC-Mmu-063840	Mus musculus	79.06	0.00e+00	993.00
IUUC-Mpu-065840	Mustela putorius furo	86.45	0.00e+00	1095.00
IUUC-Mlu-067378	Myotis lucifugus	84.46	0.00e+00	1032.00
IUUC-Ncr-068956	Neurospora crassa	33.33	3.00e-08	54.30
IUUC-Opr-070739	Ochotona princeps	81.16	0.00e+00	1001.00
IUUC-Oan-073468	Ornithorhynchus anatinus	65.98	0.00e+00	768.00
IUUC-Ocu-074343	Oryctolagus cuniculus	82.83	0.00e+00	986.00
IUUC-Oga-088276	Otolemur garnettii	79.97	0.00e+00	991.00
IUUC-Oar-090315	Ovis aries	85.28	0.00e+00	1033.00
IUUC-Ptr-091119	Pan troglodytes	95.27	0.00e+00	1227.00
IUUC-Pan-092158	Papio anubis	95.91	0.00e+00	889.00
IUUC-Psi-092959	Pelodiscus sinensis	57.74	0.00e+00	704.00
IUUC-Pab-097675	Pongo abelii	96.11	0.00e+00	1219.00
IUUC-Pca-101021	Procavia capensis	76.52	0.00e+00	920.00
IUUC-Pva-102619	Pteropus vampyrus	87.66	0.00e+00	1038.00
IUUC-Rno-105918	Rattus norvegicus	79.34	0.00e+00	1002.00
IUUC-Sha-107391	Sarcophilus harrisii	67.52	0.00e+00	870.00
IUUC-Sja-107661	Schizosaccharomyces japonicus	44.83	1.00e-10	60.80
IUUC-Sar-113148	Sorex araneus	80.23	0.00e+00	630.00
IUUC-Ssc-116219	Sus scrofa	79.25	9.00e-120	422.00
IUUC-Tgu-116584	Taeniopygia guttata	55.53	9.00e-107	380.00
IUUC-Tsy-118968	Tarsius syrichta	83.91	2.00e-164	572.00
IUUC-Tbe-128007	Tupaia belangeri	90.61	0.00e+00	811.00
IUUC-Ttr-128499	Tursiops truncatus	84.47	0.00e+00	1070.00
IUUC-Vpa-130075	Vicugna pacos	79.92	2.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence