iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065727

Ensembl Protein ID

ENSMPUP00000000647.1

UniProt Accession

M3XNJ7; M3XNJ7_MUSPF

Genbank Protein ID

ENSMPUP00000000647

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01047778

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000653.1	ENSMPUT00000000659.1	ENSMPUP00000000647.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	48.15	6.00e-09	58.90	IUUC-Dme-031659
UBD/Alpha-Helix/UBA	89.22	2.00e-178	622.00	IUUC-Hsa-046390
ULD/UDP/UFD/PB1	89.22	2.00e-178	622.00	IUUC-Hsa-046390
UBD/Alpha-Helix/UBA	86.86	4.00e-179	624.00	IUUC-Mmu-063589
UBD/Alpha-Helix/UBA	87.13	4.00e-177	617.00	IUUC-Rno-105539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

DEDGDLVAFS SDEELTMALS YVKDDIFRIY IKEKKECRRD HRPPCAQEMP RGLVHPNVIC 60
DGCNGPVVGT RYKCSVCPDY DLCAACEGKG LHREHSKLVL PAAFGPLPEG FSHSRWLRKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGAGGACG GAGACCTGGT GGCCTTTTCC AGTGACGAGG AACTGACCAT GGCACTGTCC 60
TATGTGAAGG ATGACATCTT CCGTATTTAC ATTAAAGGTA AAGGCTTGTT CTGGGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF16577--UBA_5
PF00569--ZZ

SMART

SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	92.72	1.00e-180	625.00
IUUC-Apl-003897	Anas platyrhynchos	59.48	2.00e-114	405.00
IUUC-Aca-004699	Anolis carolinensis	49.48	2.00e-85	309.00
IUUC-Ame-010982	Astyanax mexicanus	45.48	8.00e-65	241.00
IUUC-Bta-012634	Bos taurus	87.87	1.00e-180	625.00
IUUC-Cel-018660	Caenorhabditis elegans	43.75	2.00e-11	61.60
IUUC-Cja-019684	Callithrix jacchus	88.14	7.00e-174	603.00
IUUC-Cfa-020573	Canis familiaris	87.65	6.00e-147	513.00
IUUC-Cpo-021425	Cavia porcellus	78.76	2.00e-150	525.00
IUUC-Csa-023968	Chlorocebus sabaeus	88.38	4.00e-170	590.00
IUUC-Cho-024596	Choloepus hoffmanni	83.23	2.00e-52	199.00
IUUC-Cin-025557	Ciona intestinalis	25.75	2.00e-18	86.70
IUUC-Csv-025974	Ciona savignyi	57.50	6.00e-09	54.70
IUUC-Cne-027045	Cryptococcus neoformans	50.98	1.00e-09	59.30
IUUC-Dre-028621	Danio rerio	45.26	4.00e-83	301.00
IUUC-Dno-029060	Dasypus novemcinctus	86.90	0.00e+00	637.00
IUUC-Dor-030547	Dipodomys ordii	87.80	2.00e-106	379.00
IUUC-Dme-031659	Drosophila melanogaster	48.15	9.00e-10	58.50
IUUC-Ete-033201	Echinops telfairi	78.40	3.00e-157	547.00
IUUC-Eca-033456	Equus caballus	89.12	0.00e+00	656.00
IUUC-Eeu-035157	Erinaceus europaeus	83.60	9.00e-166	575.00
IUUC-Fca-035403	Felis catus	92.72	0.00e+00	639.00
IUUC-Fal-036798	Ficedula albicollis	58.48	2.00e-115	409.00
IUUC-Gmo-039619	Gadus morhua	45.15	1.00e-41	163.00
IUUC-Gga-040137	Gallus gallus	57.72	2.00e-115	408.00
IUUC-Gac-042410	Gasterosteus aculeatus	47.76	2.00e-84	306.00
IUUC-Ggo-044690	Gorilla gorilla	89.76	5.00e-172	597.00
IUUC-Hsa-046390	Homo sapiens	89.22	3.00e-171	594.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	89.49	0.00e+00	654.00
IUUC-Lch-049658	Latimeria chalumnae	50.65	1.00e-100	360.00
IUUC-Loc-052589	Lepisosteus oculatus	48.85	9.00e-98	350.00
IUUC-Laf-053746	Loxodonta africana	76.28	6.00e-152	530.00
IUUC-Mcc-055635	Macaca mulatta	88.65	3.00e-172	598.00
IUUC-Meu-056528	Macropus eugenii	50.13	1.00e-92	332.00
IUUC-Mga-059458	Meleagris gallopavo	58.99	2.00e-115	409.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	1.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	82.07	1.00e-107	383.00
IUUC-Mdo-063083	Monodelphis domestica	63.64	2.00e-127	448.00
IUUC-Mmu-063589	Mus musculus	85.79	0.00e+00	633.00
IUUC-Mlu-067026	Myotis lucifugus	86.02	2.00e-179	620.00
IUUC-Nle-069356	Nomascus leucogenys	58.03	9.00e-87	313.00
IUUC-Opr-071091	Ochotona princeps	67.91	3.00e-81	295.00
IUUC-Ont-071864	Oreochromis niloticus	50.27	8.00e-91	327.00
IUUC-Oan-073308	Ornithorhynchus anatinus	65.04	2.00e-128	452.00
IUUC-Ocu-074110	Oryctolagus cuniculus	88.71	3.00e-178	617.00
IUUC-Ola-086944	Oryzias latipes	48.17	1.00e-40	158.00
IUUC-Oga-088869	Otolemur garnettii	87.63	2.00e-175	608.00
IUUC-Oar-089857	Ovis aries	88.44	0.00e+00	629.00
IUUC-Ptr-091640	Pan troglodytes	89.22	2.00e-171	595.00
IUUC-Pan-092831	Papio anubis	89.22	3.00e-173	601.00
IUUC-Psi-093925	Pelodiscus sinensis	58.85	2.00e-113	402.00
IUUC-Pma-094576	Petromyzon marinus	33.72	4.00e-22	99.00
IUUC-Pfo-097297	Poecilia formosa	48.48	1.00e-82	300.00
IUUC-Pab-098725	Pongo abelii	78.44	3.00e-148	518.00
IUUC-Pca-101106	Procavia capensis	87.33	4.00e-166	577.00
IUUC-Pva-102710	Pteropus vampyrus	86.96	1.00e-158	552.00
IUUC-Rno-105539	Rattus norvegicus	87.13	0.00e+00	647.00
IUUC-Sha-107469	Sarcophilus harrisii	60.00	7.00e-121	427.00
IUUC-Ssc-115526	Sus scrofa	89.49	4.00e-178	617.00
IUUC-Tgu-117194	Taeniopygia guttata	59.01	1.00e-115	409.00
IUUC-Tru-117896	Takifugu rubripes	50.79	3.00e-90	325.00
IUUC-Tni-119943	Tetraodon nigroviridis	49.74	1.00e-79	290.00
IUUC-Ttr-128676	Tursiops truncatus	88.41	0.00e+00	645.00
IUUC-Vda-129812	Verticillium dahliae	36.00	3.00e-07	50.40
IUUC-Vpa-130319	Vicugna pacos	93.00	2.00e-55	208.00
IUUC-Xtr-132907	Xenopus tropicalis	54.87	5.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence