iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pma-094420

Ensembl Protein ID

ENSPMAP00000005488.1

UniProt Accession

S4RJV5; S4RJV5_PETMA

Protein Name

Tyrosine-protein kinase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000004997.1	ENSPMAT00000005508.1	ENSPMAP00000005488.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.40e-13	49.8	38	95

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W++   + ++ +G +P+n+++ ++
   Q: 38   TNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWCEV--HSRNGQGWVPSNYITPVN 95
           57899************************.*********98..899999*********997 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

EALHQPSDGD GDGPSLREAV RWNSKENLLS VPGDPDDTNL FVALYDFVAS GDNTLSITKG 60
EKLRVLGYNQ NGEWCEVHSR NGQGWVPSNY ITPVNSLEKH SWYHGPISRN AAEYLLSSGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGCCCTGC ACCAGCCCAG CGACGGGGAT GGAGACGGCC CGAGCCTCCG GGAGGCCGTG 60
CGCTGGAACT CCAAGGAGAA CCTCCTCTCC GTCCCCGGGG ACCCCGACGA CACGAACCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR033221--ABL1
IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001550	Ailuropoda melanoleuca	73.19	0.00e+00	871.00
IUUC-Apl-003452	Anas platyrhynchos	78.10	0.00e+00	874.00
IUUC-Aca-005312	Anolis carolinensis	72.02	0.00e+00	870.00
IUUC-Ame-011903	Astyanax mexicanus	77.92	0.00e+00	843.00
IUUC-Bta-012351	Bos taurus	78.16	0.00e+00	866.00
IUUC-Cja-019491	Callithrix jacchus	73.56	0.00e+00	872.00
IUUC-Cfa-021256	Canis familiaris	72.87	0.00e+00	870.00
IUUC-Cpo-022046	Cavia porcellus	73.56	0.00e+00	868.00
IUUC-Csa-023046	Chlorocebus sabaeus	51.72	0.00e+00	913.00
IUUC-Cho-024714	Choloepus hoffmanni	75.71	0.00e+00	843.00
IUUC-Dre-028190	Danio rerio	84.53	0.00e+00	824.00
IUUC-Dno-029853	Dasypus novemcinctus	78.52	0.00e+00	873.00
IUUC-Dor-030416	Dipodomys ordii	61.15	0.00e+00	698.00
IUUC-Dme-032098	Drosophila melanogaster	69.89	0.00e+00	723.00
IUUC-Ete-032899	Echinops telfairi	80.16	1.00e-108	386.00
IUUC-Eca-033720	Equus caballus	73.19	0.00e+00	873.00
IUUC-Eeu-035173	Erinaceus europaeus	68.53	0.00e+00	796.00
IUUC-Fca-035967	Felis catus	73.56	0.00e+00	869.00
IUUC-Fal-036723	Ficedula albicollis	77.74	0.00e+00	873.00
IUUC-Gmo-039550	Gadus morhua	72.44	0.00e+00	828.00
IUUC-Gga-040481	Gallus gallus	77.92	0.00e+00	872.00
IUUC-Gac-041643	Gasterosteus aculeatus	71.77	0.00e+00	838.00
IUUC-Ggo-045299	Gorilla gorilla	73.40	0.00e+00	871.00
IUUC-Hsa-047033	Homo sapiens	73.33	3.00e-27	111.00
IUUC-Itr-047935	Ictidomys tridecemlineatus	73.19	0.00e+00	877.00
IUUC-Lch-050530	Latimeria chalumnae	72.52	0.00e+00	855.00
IUUC-Loc-051933	Lepisosteus oculatus	68.78	0.00e+00	859.00
IUUC-Laf-053609	Loxodonta africana	78.52	0.00e+00	874.00
IUUC-Mcc-055654	Macaca mulatta	51.59	0.00e+00	913.00
IUUC-Meu-056488	Macropus eugenii	64.50	0.00e+00	669.00
IUUC-Mga-059270	Meleagris gallopavo	77.88	0.00e+00	873.00
IUUC-Mmr-060593	Microcebus murinus	73.30	0.00e+00	872.00
IUUC-Mdo-062227	Monodelphis domestica	78.38	0.00e+00	861.00
IUUC-Mmu-064002	Mus musculus	72.13	0.00e+00	872.00
IUUC-Mpu-066197	Mustela putorius furo	72.71	0.00e+00	867.00
IUUC-Mlu-067255	Myotis lucifugus	78.30	0.00e+00	863.00
IUUC-Nle-070062	Nomascus leucogenys	71.02	0.00e+00	847.00
IUUC-Opr-070327	Ochotona princeps	66.24	0.00e+00	743.00
IUUC-Ont-072307	Oreochromis niloticus	75.85	0.00e+00	835.00
IUUC-Oan-073100	Ornithorhynchus anatinus	78.34	0.00e+00	868.00
IUUC-Ocu-074051	Oryctolagus cuniculus	69.77	0.00e+00	848.00
IUUC-Ola-087389	Oryzias latipes	77.68	0.00e+00	862.00
IUUC-Oga-088145	Otolemur garnettii	78.52	0.00e+00	869.00
IUUC-Oar-090432	Ovis aries	72.40	0.00e+00	856.00
IUUC-Ptr-090800	Pan troglodytes	73.40	0.00e+00	872.00
IUUC-Pan-092279	Papio anubis	68.30	0.00e+00	849.00
IUUC-Psi-093078	Pelodiscus sinensis	51.91	0.00e+00	915.00
IUUC-Pfo-096979	Poecilia formosa	79.46	0.00e+00	835.00
IUUC-Pab-097949	Pongo abelii	70.23	0.00e+00	850.00
IUUC-Pca-100874	Procavia capensis	85.21	2.00e-165	575.00
IUUC-Pva-102415	Pteropus vampyrus	73.32	0.00e+00	859.00
IUUC-Rno-105370	Rattus norvegicus	77.98	0.00e+00	870.00
IUUC-Sha-106711	Sarcophilus harrisii	77.70	0.00e+00	867.00
IUUC-Ssc-115472	Sus scrofa	73.64	0.00e+00	872.00
IUUC-Tgu-117037	Taeniopygia guttata	72.68	0.00e+00	870.00
IUUC-Tru-118410	Takifugu rubripes	68.85	0.00e+00	832.00
IUUC-Tsy-119216	Tarsius syrichta	81.35	0.00e+00	857.00
IUUC-Tni-119991	Tetraodon nigroviridis	68.37	0.00e+00	824.00
IUUC-Tbe-127362	Tupaia belangeri	68.93	0.00e+00	833.00
IUUC-Ttr-128209	Tursiops truncatus	73.48	0.00e+00	872.00
IUUC-Vpa-130800	Vicugna pacos	68.01	0.00e+00	845.00
IUUC-Xtr-132965	Xenopus tropicalis	73.20	0.00e+00	833.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence