iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115724

Ensembl Protein ID

ENSSSCP00000022636.1

UniProt Accession

I3LEZ7; I3LEZ7_PIG

Genbank Protein ID

ENSSSCP00000022636

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

FP565308

Gene Name

HDAC6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000025545.1	ENSSSCT00000022405.1	ENSSSCP00000022636.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/ZnF/ZnF_UBP	75.96	0.00e+00	1655.00	IUUC-Hsa-046904

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

NRVRGEVSPA MTSTGQDSTT TRQRRSRHNP HSPPHDSSVT SKRGVKKGAG LRSSPNLADV 60
KKKGRMKKLS QAAEQDLIVG LQGLDLNLEA RTPSGTGLVL DEQLNEFHCL WDDSFPEGPE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACATTTGGTG AGTGCTTCCT TGCGTACCAC CTTAGTGAAT ATGAACTCAG AAAATTCTCA 60
CATTTGTCAT CATCACCACT CCCTTTTTGG CCGCCACCAG CCTCGTCCAA TTTCCACCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000286--His_deacetylse
IPR023801--His_deacetylse_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50271--ZF_UBP

Pfam

PF00850--Hist_deacetyl
PF02148--zf-UBP

PRINTS

PR01270--HDASUPER

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0016235--C:aggresome
GO:0030424--C:axon
GO:0005901--C:caveola
GO:0031252--C:cell leading edge
GO:0005881--C:cytoplasmic microtubule
GO:0005829--C:cytosol
GO:0030425--C:dendrite
GO:0030286--C:dynein complex
GO:0000118--C:histone deacetylase complex
GO:0043204--C:perikaryon
GO:0048471--C:perinuclear region of cytoplasm
GO:0001047--F:core promoter binding
GO:0004407--F:histone deacetylase activity
GO:0042903--F:tubulin deacetylase activity
GO:0008270--F:zinc ion binding
GO:0070842--P:aggresome assembly
GO:0070301--P:cellular response to hydrogen peroxide
GO:0071218--P:cellular response to misfolded protein
GO:0048668--P:collateral sprouting
GO:0060997--P:dendritic spine morphogenesis
GO:0070846--P:Hsp90 deacetylation
GO:0032418--P:lysosome localization
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0051646--P:mitochondrion localization
GO:0007026--P:negative regulation of microtubule depolymerization
GO:0045861--P:negative regulation of proteolysis
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:0034983--P:peptidyl-lysine deacetylation
GO:0070845--P:polyubiquitinated misfolded protein transport
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0010634--P:positive regulation of epithelial cell migration
GO:1901300--P:positive regulation of hydrogen peroxide-mediated programmed cell death
GO:0010870--P:positive regulation of receptor biosynthetic process
GO:0009967--P:positive regulation of signal transduction
GO:0043241--P:protein complex disassembly
GO:0000209--P:protein polyubiquitination
GO:0070201--P:regulation of establishment of protein localization
GO:0045598--P:regulation of fat cell differentiation
GO:0040029--P:regulation of gene expression, epigenetic
GO:0031647--P:regulation of protein stability
GO:0010469--P:regulation of receptor activity
GO:0070848--P:response to growth factor
GO:0009636--P:response to toxic substance
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000749	Aegilops tauschii	41.30	8.00e-70	257.00
IUUC-Aml-002087	Ailuropoda melanoleuca	82.46	0.00e+00	1848.00
IUUC-Atr-002745	Amborella trichopoda	45.03	2.00e-79	290.00
IUUC-Aca-004303	Anolis carolinensis	58.32	0.00e+00	990.00
IUUC-Aly-006432	Arabidopsis lyrata	46.48	9.00e-81	294.00
IUUC-Ath-007355	Arabidopsis thaliana	40.52	2.00e-81	296.00
IUUC-Ago-007972	Ashbya gossypii	40.96	4.00e-75	275.00
IUUC-Acl-008187	Aspergillus clavatus	45.72	5.00e-81	295.00
IUUC-Afl-008399	Aspergillus flavus	54.49	3.00e-46	179.00
IUUC-Afu-008954	Aspergillus fumigatus	40.30	2.00e-70	259.00
IUUC-Ani-009142	Aspergillus nidulans	43.28	2.00e-73	270.00
IUUC-Ang-009522	Aspergillus niger	34.76	1.00e-41	164.00
IUUC-Aor-010069	Aspergillus oryzae	43.67	2.00e-72	266.00
IUUC-Ate-010291	Aspergillus terreus	44.65	2.00e-80	293.00
IUUC-Ame-010780	Astyanax mexicanus	46.37	0.00e+00	920.00
IUUC-Bta-013052	Bos taurus	81.52	0.00e+00	1755.00
IUUC-Bci-013789	Botrytis cinerea	41.27	8.00e-78	285.00
IUUC-Bdi-014007	Brachypodium distachyon	45.85	4.00e-83	302.00
IUUC-Bol-015468	Brassica oleracea	42.45	1.00e-79	290.00
IUUC-Bra-016680	Brassica rapa	44.41	2.00e-79	290.00
IUUC-Cel-018220	Caenorhabditis elegans	38.33	1.00e-141	497.00
IUUC-Cja-019473	Callithrix jacchus	80.46	0.00e+00	1403.00
IUUC-Cfa-020263	Canis familiaris	82.34	0.00e+00	1795.00
IUUC-Cpo-021691	Cavia porcellus	77.72	0.00e+00	1732.00
IUUC-Csa-024223	Chlorocebus sabaeus	84.46	0.00e+00	1494.00
IUUC-Cgl-026709	Colletotrichum gloeosporioides	39.90	1.00e-73	270.00
IUUC-Cne-026978	Cryptococcus neoformans	44.44	5.00e-81	295.00
IUUC-Dre-028820	Danio rerio	51.60	0.00e+00	1056.00
IUUC-Dno-029160	Dasypus novemcinctus	73.13	0.00e+00	1598.00
IUUC-Dor-030859	Dipodomys ordii	67.89	0.00e+00	1548.00
IUUC-Dse-031186	Dothistroma septosporum	40.93	4.00e-71	262.00
IUUC-Dme-031963	Drosophila melanogaster	44.76	0.00e+00	667.00
IUUC-Ete-032279	Echinops telfairi	66.19	2.00e-149	522.00
IUUC-Eca-033842	Equus caballus	81.66	0.00e+00	1861.00
IUUC-Eeu-034487	Erinaceus europaeus	77.81	1.00e-158	553.00
IUUC-Fca-036430	Felis catus	82.53	0.00e+00	1786.00
IUUC-Fox-038067	Fusarium oxysporum	41.04	2.00e-76	280.00
IUUC-Fso-038263	Fusarium solani	42.38	5.00e-77	281.00
IUUC-Ggr-040062	Gaeumannomyces graminis	41.54	1.00e-73	270.00
IUUC-Gma-043738	Glycine max	48.93	4.00e-84	305.00
IUUC-Ggo-045022	Gorilla gorilla	85.15	0.00e+00	1499.00
IUUC-Hsa-046904	Homo sapiens	75.74	0.00e+00	1690.00
IUUC-Hvu-047285	Hordeum vulgare	45.23	2.00e-80	292.00
IUUC-Itr-048484	Ictidomys tridecemlineatus	78.26	0.00e+00	1748.00
IUUC-Kpa-049281	Komagataella pastoris	41.27	3.00e-78	286.00
IUUC-Lch-050330	Latimeria chalumnae	47.33	0.00e+00	940.00
IUUC-Lpe-051214	Leersia perrieri	46.75	3.00e-83	302.00
IUUC-Lma-053263	Leptosphaeria maculans	45.55	7.00e-83	301.00
IUUC-Laf-053386	Loxodonta africana	78.29	0.00e+00	1692.00
IUUC-Mcc-055530	Macaca mulatta	75.91	0.00e+00	1699.00
IUUC-Meu-056442	Macropus eugenii	68.60	0.00e+00	954.00
IUUC-Mor-057095	Magnaporthe oryzae	41.44	4.00e-81	295.00
IUUC-Mpo-057389	Magnaporthe poae	42.45	2.00e-73	270.00
IUUC-Mtr-058463	Medicago truncatula	47.85	6.00e-85	308.00
IUUC-Mla-059143	Melampsora laricipopulina	42.63	3.00e-78	285.00
IUUC-Mmr-060637	Microcebus murinus	84.64	0.00e+00	1535.00
IUUC-Mdo-062198	Monodelphis domestica	62.25	0.00e+00	1249.00
IUUC-Mmu-063346	Mus musculus	72.64	0.00e+00	1626.00
IUUC-Mac-064630	Musa acuminata	45.26	2.00e-80	293.00
IUUC-Mpu-065884	Mustela putorius furo	81.86	0.00e+00	1841.00
IUUC-Mlu-068117	Myotis lucifugus	79.21	0.00e+00	1768.00
IUUC-Nfi-068404	Neosartorya fischeri	45.45	1.00e-81	297.00
IUUC-Ncr-068672	Neurospora crassa	41.81	6.00e-77	281.00
IUUC-Nle-069868	Nomascus leucogenys	93.77	0.00e+00	756.00
IUUC-Opr-071074	Ochotona princeps	62.12	0.00e+00	918.00
IUUC-Ont-072246	Oreochromis niloticus	52.94	0.00e+00	764.00
IUUC-Oan-072911	Ornithorhynchus anatinus	72.11	5.00e-107	382.00
IUUC-Ocu-074627	Oryctolagus cuniculus	77.42	0.00e+00	1751.00
IUUC-Oba-075489	Oryza barthii	46.15	4.00e-82	298.00
IUUC-Obr-076150	Oryza brachyantha	46.30	2.00e-82	300.00
IUUC-Ogl-077437	Oryza glaberrima	46.15	3.00e-82	299.00
IUUC-Ogu-078370	Oryza glumaepatula	46.15	8.00e-83	301.00
IUUC-Oin-079210	Oryza indica	46.15	8.00e-83	301.00
IUUC-Olo-080971	Oryza longistaminata	46.95	3.00e-71	262.00
IUUC-Oni-082031	Oryza nivara	46.15	2.00e-82	300.00
IUUC-Opu-083471	Oryza punctata	45.73	5.00e-82	298.00
IUUC-Oru-084755	Oryza rufipogon	46.15	8.00e-83	301.00
IUUC-Osa-085447	Oryza sativa	46.15	8.00e-83	301.00
IUUC-Oga-089155	Otolemur garnettii	82.21	0.00e+00	1477.00
IUUC-Oar-089620	Ovis aries	81.60	0.00e+00	1770.00
IUUC-Ptr-090812	Pan troglodytes	88.73	0.00e+00	1240.00
IUUC-Pan-092340	Papio anubis	75.99	0.00e+00	1694.00
IUUC-Pma-094386	Petromyzon marinus	53.54	0.00e+00	800.00
IUUC-Pno-095131	Phaeosphaeria nodorum	47.62	4.00e-68	251.00
IUUC-Ppa-095550	Physcomitrella patens	47.13	2.00e-85	310.00
IUUC-Pfo-096110	Poecilia formosa	47.94	0.00e+00	834.00
IUUC-Pab-098422	Pongo abelii	74.87	0.00e+00	1641.00
IUUC-Pop-099174	Populus trichocarpa	45.06	3.00e-78	286.00
IUUC-Pca-100833	Procavia capensis	74.98	0.00e+00	1546.00
IUUC-Ppe-101644	Prunus persica	43.58	5.00e-83	301.00
IUUC-Pva-102410	Pteropus vampyrus	76.44	0.00e+00	1628.00
IUUC-Ptt-103841	Puccinia triticina	39.29	1.00e-73	271.00
IUUC-Pte-104383	Pyrenophora teres	43.85	3.00e-77	283.00
IUUC-Pyt-104427	Pyrenophora triticirepentis	44.39	7.00e-78	285.00
IUUC-Rno-105131	Rattus norvegicus	73.29	0.00e+00	1621.00
IUUC-Sce-106274	Saccharomyces cerevisiae	41.22	5.00e-78	285.00
IUUC-Sha-106661	Sarcophilus harrisii	56.00	0.00e+00	828.00
IUUC-Sja-107915	Schizosaccharomyces japonicus	43.09	6.00e-82	298.00
IUUC-Spo-108300	Schizosaccharomyces pombe	45.48	1.00e-81	297.00
IUUC-Smo-109615	Selaginella moellendorffii	43.31	3.00e-86	312.00
IUUC-Sit-110160	Setaria italica	41.75	1.00e-78	287.00
IUUC-Sly-111164	Solanum lycopersicum	40.17	2.00e-78	286.00
IUUC-Stu-112685	Solanum tuberosum	42.51	3.00e-69	255.00
IUUC-Sar-113692	Sorex araneus	68.23	0.00e+00	777.00
IUUC-Sbi-114301	Sorghum bicolor	46.15	6.00e-78	285.00
IUUC-Sre-115013	Sporisorium reilianum	42.78	2.00e-77	283.00
IUUC-Tgu-116605	Taeniopygia guttata	48.13	0.00e+00	660.00
IUUC-Tru-117614	Takifugu rubripes	54.69	0.00e+00	837.00
IUUC-Tsy-118807	Tarsius syrichta	75.44	0.00e+00	784.00
IUUC-Tni-119809	Tetraodon nigroviridis	56.01	0.00e+00	790.00
IUUC-Tca-121312	Theobroma cacao	46.48	2.00e-81	296.00
IUUC-Tre-121930	Trichoderma reesei	41.71	3.00e-78	286.00
IUUC-Tvi-122373	Trichoderma virens	41.71	2.00e-78	286.00
IUUC-Tae-123064	Triticum aestivum	42.39	2.00e-76	278.00
IUUC-Tme-127027	Tuber melanosporum	41.53	2.00e-64	239.00
IUUC-Tbe-127675	Tupaia belangeri	54.09	6.00e-73	268.00
IUUC-Ttr-128411	Tursiops truncatus	82.98	0.00e+00	1793.00
IUUC-Uma-129408	Ustilago maydis	46.43	1.00e-71	264.00
IUUC-Vda-129994	Verticillium dahliae	39.49	2.00e-69	256.00
IUUC-Vpa-130525	Vicugna pacos	88.30	2.00e-61	230.00
IUUC-Vvi-131038	Vitis vinifera	44.58	7.00e-82	298.00
IUUC-Xtr-132618	Xenopus tropicalis	49.87	0.00e+00	1054.00
IUUC-Xma-133730	Xiphophorus maculatus	48.76	0.00e+00	690.00
IUUC-Yli-134680	Yarrowia lipolytica	40.19	3.00e-78	286.00
IUUC-Zma-135110	Zea mays	45.99	9.00e-79	287.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence