iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106579

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01080157

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000010692.1	ENSSHAT00000012591.1	ENSSHAP00000012489.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.20e-27	93.4	179	252

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 179  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 252
           69********************************************************************9986 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

TRNPLVAVYY TNRALCYLKM QQHDKALADC KHALELDGQS VKAHFFLGQC QLEMENYDEA 60
IANLQRAYNL AKEQRLNFGD DIPSALRIAK KKRWNSIEER RIHQENELHA YLTKLIMAER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCGAAATC CCCTTGTGGC TGTTTATTAC ACCAACCGGG CACTGTGCTA TCTGAAGATG 60
CAGCAGCATG ACAAGGCTCT GGCCGACTGC AAGCATGCCC TAGAGCTGGA CGGCCAGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	33.99	2.00e-37	149.00
IUUC-Aml-001350	Ailuropoda melanoleuca	90.62	4.00e-135	473.00
IUUC-Atr-003168	Amborella trichopoda	35.02	4.00e-31	127.00
IUUC-Apl-003736	Anas platyrhynchos	90.23	2.00e-137	481.00
IUUC-Aca-004751	Anolis carolinensis	90.62	4.00e-136	477.00
IUUC-Aly-006292	Arabidopsis lyrata	32.41	7.00e-38	150.00
IUUC-Ath-007012	Arabidopsis thaliana	32.41	2.00e-37	149.00
IUUC-Acl-008025	Aspergillus clavatus	30.00	9.00e-30	123.00
IUUC-Afl-008721	Aspergillus flavus	29.66	3.00e-26	111.00
IUUC-Afu-008853	Aspergillus fumigatus	29.62	8.00e-29	120.00
IUUC-Ani-009349	Aspergillus nidulans	30.37	2.00e-28	119.00
IUUC-Ang-009674	Aspergillus niger	31.06	6.00e-26	110.00
IUUC-Aor-010014	Aspergillus oryzae	29.66	3.00e-26	111.00
IUUC-Ate-010467	Aspergillus terreus	27.00	7.00e-21	94.00
IUUC-Ame-011215	Astyanax mexicanus	60.31	1.00e-81	295.00
IUUC-Bgr-011971	Blumeria graminis	28.29	2.00e-20	92.40
IUUC-Bta-013025	Bos taurus	90.55	7.00e-134	469.00
IUUC-Bci-013945	Botrytis cinerea	39.51	6.00e-15	74.30
IUUC-Bdi-014483	Brachypodium distachyon	37.35	9.00e-41	160.00
IUUC-Bol-015676	Brassica oleracea	33.33	4.00e-38	152.00
IUUC-Bra-017897	Brassica rapa	31.16	3.00e-28	117.00
IUUC-Cel-018323	Caenorhabditis elegans	40.48	4.00e-49	187.00
IUUC-Cja-019657	Callithrix jacchus	88.28	1.00e-132	465.00
IUUC-Cfa-020470	Canis familiaris	89.87	6.00e-123	432.00
IUUC-Cpo-022033	Cavia porcellus	89.45	2.00e-133	468.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	26.24	6.00e-21	94.00
IUUC-Csa-023038	Chlorocebus sabaeus	89.45	1.00e-126	445.00
IUUC-Cin-025381	Ciona intestinalis	53.52	3.00e-77	281.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	31.52	5.00e-33	134.00
IUUC-Dre-027610	Danio rerio	82.03	3.00e-124	437.00
IUUC-Dno-030087	Dasypus novemcinctus	91.02	6.00e-136	476.00
IUUC-Dor-031029	Dipodomys ordii	82.81	4.00e-119	420.00
IUUC-Dse-031275	Dothistroma septosporum	29.39	2.00e-19	89.70
IUUC-Dme-031856	Drosophila melanogaster	54.51	6.00e-80	290.00
IUUC-Ete-033087	Echinops telfairi	85.78	2.00e-111	394.00
IUUC-Eca-033512	Equus caballus	90.23	2.00e-134	471.00
IUUC-Eeu-034763	Erinaceus europaeus	87.37	3.00e-92	330.00
IUUC-Fca-036460	Felis catus	91.02	2.00e-135	474.00
IUUC-Fal-037441	Ficedula albicollis	90.62	1.00e-137	482.00
IUUC-Fox-038028	Fusarium oxysporum	29.15	5.00e-31	127.00
IUUC-Fso-038323	Fusarium solani	31.76	2.00e-24	105.00
IUUC-Gmo-038511	Gadus morhua	79.69	6.00e-119	419.00
IUUC-Ggr-039964	Gaeumannomyces graminis	33.20	3.00e-22	99.00
IUUC-Gga-040854	Gallus gallus	90.62	7.00e-138	483.00
IUUC-Gac-042175	Gasterosteus aculeatus	79.30	5.00e-116	409.00
IUUC-Gma-044046	Glycine max	35.29	4.00e-37	148.00
IUUC-Ggo-044512	Gorilla gorilla	89.45	1.00e-126	445.00
IUUC-Hsa-046872	Homo sapiens	89.45	1.00e-126	445.00
IUUC-Hvu-047372	Hordeum vulgare	35.20	6.00e-38	150.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	89.06	8.00e-133	466.00
IUUC-Lch-049988	Latimeria chalumnae	84.38	4.00e-121	427.00
IUUC-Lpe-050693	Leersia perrieri	35.32	8.00e-39	153.00
IUUC-Loc-052195	Lepisosteus oculatus	81.64	1.00e-119	422.00
IUUC-Lma-053207	Leptosphaeria maculans	27.86	8.00e-21	95.50
IUUC-Laf-054584	Loxodonta africana	89.06	1.00e-134	471.00
IUUC-Mcc-054689	Macaca mulatta	89.45	1.00e-126	445.00
IUUC-Meu-055998	Macropus eugenii	98.35	1.00e-67	249.00
IUUC-Mor-057116	Magnaporthe oryzae	34.12	4.00e-33	134.00
IUUC-Mtr-057684	Medicago truncatula	33.33	5.00e-34	137.00
IUUC-Mga-059332	Meleagris gallopavo	90.62	5.00e-138	483.00
IUUC-Mmr-061377	Microcebus murinus	89.84	6.00e-127	446.00
IUUC-Mdo-061963	Monodelphis domestica	97.27	4.00e-136	476.00
IUUC-Mmu-063146	Mus musculus	89.06	3.00e-125	441.00
IUUC-Mac-064932	Musa acuminata	48.00	4.00e-27	114.00
IUUC-Mpu-066418	Mustela putorius furo	90.62	3.00e-135	474.00
IUUC-Mlu-067066	Myotis lucifugus	90.23	2.00e-135	474.00
IUUC-Nfi-068601	Neosartorya fischeri	29.62	1.00e-28	120.00
IUUC-Ncr-068761	Neurospora crassa	41.67	4.00e-17	81.60
IUUC-Nle-069374	Nomascus leucogenys	89.45	1.00e-126	445.00
IUUC-Opr-070765	Ochotona princeps	85.19	2.00e-92	330.00
IUUC-Ont-071996	Oreochromis niloticus	82.03	3.00e-119	421.00
IUUC-Oba-075967	Oryza barthii	36.65	1.00e-38	153.00
IUUC-Obr-076709	Oryza brachyantha	35.14	1.00e-30	125.00
IUUC-Ogl-076959	Oryza glaberrima	35.66	2.00e-39	155.00
IUUC-Ogu-078247	Oryza glumaepatula	35.66	2.00e-39	155.00
IUUC-Oin-079616	Oryza indica	35.66	2.00e-39	155.00
IUUC-Olo-080492	Oryza longistaminata	33.18	2.00e-28	121.00
IUUC-Ome-081935	Oryza meridionalis	28.29	5.00e-19	90.50
IUUC-Oni-082535	Oryza nivara	35.66	2.00e-39	155.00
IUUC-Opu-083794	Oryza punctata	36.65	3.00e-38	152.00
IUUC-Oru-085166	Oryza rufipogon	35.66	2.00e-39	155.00
IUUC-Osa-085936	Oryza sativa	35.51	1.00e-12	66.20
IUUC-Ola-087081	Oryzias latipes	80.47	4.00e-122	430.00
IUUC-Olu-087790	Ostreococcus lucimarinus	28.79	2.00e-25	109.00
IUUC-Oga-088331	Otolemur garnettii	89.84	2.00e-127	447.00
IUUC-Oar-089987	Ovis aries	90.27	2.00e-134	471.00
IUUC-Ptr-090855	Pan troglodytes	89.45	1.00e-126	445.00
IUUC-Pan-092801	Papio anubis	83.59	1.00e-125	442.00
IUUC-Psi-093393	Pelodiscus sinensis	91.02	9.00e-140	488.00
IUUC-Pma-094680	Petromyzon marinus	69.38	1.00e-100	358.00
IUUC-Pno-094913	Phaeosphaeria nodorum	31.84	3.00e-27	115.00
IUUC-Ppa-095508	Physcomitrella patens	33.33	8.00e-41	160.00
IUUC-Pfo-096850	Poecilia formosa	79.69	5.00e-116	410.00
IUUC-Pab-097963	Pongo abelii	89.45	1.00e-126	445.00
IUUC-Pop-098805	Populus trichocarpa	43.88	5.00e-25	107.00
IUUC-Pca-100788	Procavia capensis	89.45	3.00e-135	474.00
IUUC-Ppe-101221	Prunus persica	33.98	2.00e-38	152.00
IUUC-Pva-103076	Pteropus vampyrus	89.84	5.00e-134	469.00
IUUC-Pte-104237	Pyrenophora teres	30.89	8.00e-26	110.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	30.89	7.00e-26	110.00
IUUC-Rno-105204	Rattus norvegicus	88.67	7.00e-125	439.00
IUUC-Smo-109215	Selaginella moellendorffii	34.12	1.00e-36	146.00
IUUC-Sit-110665	Setaria italica	34.62	3.00e-39	155.00
IUUC-Sly-111473	Solanum lycopersicum	34.88	1.00e-38	152.00
IUUC-Stu-112353	Solanum tuberosum	34.38	3.00e-37	148.00
IUUC-Sbi-114250	Sorghum bicolor	37.80	4.00e-41	161.00
IUUC-Ssc-115416	Sus scrofa	90.62	2.00e-135	474.00
IUUC-Tgu-117272	Taeniopygia guttata	95.37	8.00e-58	214.00
IUUC-Tru-117777	Takifugu rubripes	80.47	8.00e-118	416.00
IUUC-Tni-120572	Tetraodon nigroviridis	80.47	4.00e-117	413.00
IUUC-Tca-121149	Theobroma cacao	37.25	8.00e-43	166.00
IUUC-Tre-122230	Trichoderma reesei	41.18	1.00e-16	80.10
IUUC-Tvi-122678	Trichoderma virens	33.72	1.00e-35	142.00
IUUC-Tae-123820	Triticum aestivum	35.60	2.00e-38	152.00
IUUC-Tur-126009	Triticum urartu	33.07	1.00e-37	150.00
IUUC-Tme-126948	Tuber melanosporum	36.25	2.00e-37	149.00
IUUC-Ttr-129031	Tursiops truncatus	90.62	4.00e-135	473.00
IUUC-Vda-130023	Verticillium dahliae	31.85	5.00e-33	134.00
IUUC-Vvi-131091	Vitis vinifera	48.91	1.00e-25	108.00
IUUC-Xtr-132871	Xenopus tropicalis	84.38	1.00e-118	418.00
IUUC-Xma-134220	Xiphophorus maculatus	79.69	6.00e-116	409.00
IUUC-Yli-134462	Yarrowia lipolytica	27.41	2.00e-21	96.30
IUUC-Zma-135773	Zea mays	36.96	3.00e-41	161.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence