iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011887

Ensembl Protein ID

ENSAMXP00000014947.1

UniProt Accession

W5L535; W5L535_ASTMX

Genbank Protein ID

ENSAMXP00000014947

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01085644

Gene Name

SRC (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000014517.1	ENSAMXT00000014947.1	ENSAMXP00000014947.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-13	51.2	93	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ ++ +Lt+kkG+ ++++  ++++++W+ + + ++g +G +P+n+v+ 
   Q: 93   TFVALYDYESRTSADLTFKKGERLQIL--NNTEGDWWLARSLTTGESGYIPSNYVAP 147
           5789***********************..8999*********************975 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGTGKSKEGK GKDPGQRSLS LDGTIGMGSS SGHHFSSGPQ TQTPNRSPAV GSSTRINTYH 60
PNNTDHPQLF GGVDHPGSIM SPQRGKYITG VTTFVALYDY ESRTSADLTF KKGERLQILN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGACGG GGAAGAGTAA AGAGGGGAAG GGGAAAGATC CGGGACAGCG TTCCCTCAGT 60
CTGGACGGAA CCATAGGTAT GGGTTCCTCT AGTGGACACC ATTTCAGTTC CGGCCCCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001713	Ailuropoda melanoleuca	78.65	0.00e+00	881.00
IUUC-Aca-004237	Anolis carolinensis	79.34	0.00e+00	888.00
IUUC-Bta-012982	Bos taurus	79.27	0.00e+00	883.00
IUUC-Cja-019995	Callithrix jacchus	78.28	0.00e+00	875.00
IUUC-Cfa-020060	Canis familiaris	79.52	0.00e+00	887.00
IUUC-Cpo-021557	Cavia porcellus	79.89	0.00e+00	880.00
IUUC-Csa-023711	Chlorocebus sabaeus	78.28	0.00e+00	874.00
IUUC-Dre-028491	Danio rerio	84.35	0.00e+00	897.00
IUUC-Dno-029651	Dasypus novemcinctus	77.26	0.00e+00	861.00
IUUC-Ete-033170	Echinops telfairi	86.03	0.00e+00	823.00
IUUC-Eca-033970	Equus caballus	89.14	0.00e+00	858.00
IUUC-Fca-036113	Felis catus	79.52	0.00e+00	887.00
IUUC-Fal-036785	Ficedula albicollis	78.47	0.00e+00	877.00
IUUC-Gga-040899	Gallus gallus	79.70	0.00e+00	887.00
IUUC-Gac-041976	Gasterosteus aculeatus	85.97	0.00e+00	960.00
IUUC-Hsa-046192	Homo sapiens	78.47	0.00e+00	875.00
IUUC-Itr-049014	Ictidomys tridecemlineatus	78.28	0.00e+00	876.00
IUUC-Lch-049892	Latimeria chalumnae	79.04	0.00e+00	876.00
IUUC-Loc-052812	Lepisosteus oculatus	85.16	0.00e+00	920.00
IUUC-Laf-053977	Loxodonta africana	78.83	0.00e+00	882.00
IUUC-Mcc-055159	Macaca mulatta	76.74	0.00e+00	868.00
IUUC-Mga-060135	Meleagris gallopavo	78.83	0.00e+00	879.00
IUUC-Mmr-061168	Microcebus murinus	77.10	0.00e+00	871.00
IUUC-Mdo-063030	Monodelphis domestica	77.46	0.00e+00	877.00
IUUC-Mmu-063893	Mus musculus	77.92	0.00e+00	874.00
IUUC-Mpu-066411	Mustela putorius furo	79.52	0.00e+00	887.00
IUUC-Mlu-068139	Myotis lucifugus	78.28	0.00e+00	877.00
IUUC-Nle-070178	Nomascus leucogenys	76.46	0.00e+00	840.00
IUUC-Ont-072130	Oreochromis niloticus	85.90	0.00e+00	959.00
IUUC-Ocu-074403	Oryctolagus cuniculus	78.14	0.00e+00	876.00
IUUC-Ola-086527	Oryzias latipes	85.71	0.00e+00	951.00
IUUC-Oga-088493	Otolemur garnettii	78.10	0.00e+00	875.00
IUUC-Oar-090279	Ovis aries	79.23	0.00e+00	883.00
IUUC-Ptr-091050	Pan troglodytes	78.47	0.00e+00	875.00
IUUC-Pan-091862	Papio anubis	79.15	0.00e+00	880.00
IUUC-Psi-093071	Pelodiscus sinensis	79.52	0.00e+00	889.00
IUUC-Pfo-096578	Poecilia formosa	86.62	0.00e+00	965.00
IUUC-Pab-097902	Pongo abelii	77.10	0.00e+00	870.00
IUUC-Rno-105847	Rattus norvegicus	78.32	0.00e+00	876.00
IUUC-Sha-107539	Sarcophilus harrisii	79.34	0.00e+00	884.00
IUUC-Ssc-115762	Sus scrofa	78.22	0.00e+00	876.00
IUUC-Tru-117854	Takifugu rubripes	84.63	0.00e+00	938.00
IUUC-Tni-120843	Tetraodon nigroviridis	87.02	0.00e+00	961.00
IUUC-Ttr-128702	Tursiops truncatus	73.14	0.00e+00	800.00
IUUC-Xtr-132291	Xenopus tropicalis	77.76	0.00e+00	836.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence