iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041976

Ensembl Protein ID

ENSGACP00000007343.1

UniProt Accession

G3NPS8; G3NPS8_GASAC

Protein Name

Tyrosine-protein kinase

Gene Name

SRC (1 of many)

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000005548.1	ENSGACT00000007361.1	ENSGACP00000007343.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.60e-13	49.7	94	148

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +Lt++kGd ++++  ++++++W+ + + ++g +G +P+n+v+ 
   Q: 94   TFVALYDYESRTASDLTFRKGDRLQIV--NHTEGDWWLARSLTTGESGYIPSNYVAP 148
           6789***********************..88999********************975 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MGAGKSKPKE PGQRSMSLDG TIGTGSDSGH FHHLGPAQQT QTPNRSPAVG TGRRGHGHQG 60
QHQLAPTNTP VLALFGGVDH TGTVTSPHRG GVTTFVALYD YESRTASDLT FRKGDRLQIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGCGG GCAAGAGCAA GCCCAAGGAG CCGGGCCAGC GCTCCATGAG CCTGGACGGC 60
ACCATCGGCA CCGGCTCCGA CAGCGGCCAC TTCCACCACC TGGGACCGGC CCAGCAGACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011887	Astyanax mexicanus	85.97	0.00e+00	959.00
IUUC-Ete-033170	Echinops telfairi	86.46	0.00e+00	830.00
IUUC-Gmo-038707	Gadus morhua	77.68	0.00e+00	848.00
IUUC-Ont-072130	Oreochromis niloticus	94.57	0.00e+00	1055.00
IUUC-Ola-086527	Oryzias latipes	93.30	0.00e+00	1040.00
IUUC-Pfo-096578	Poecilia formosa	94.02	0.00e+00	1070.00
IUUC-Tru-117854	Takifugu rubripes	91.30	0.00e+00	1012.00
IUUC-Tni-120843	Tetraodon nigroviridis	95.42	0.00e+00	1076.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence