iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-072666

Ensembl Protein ID

ENSONIP00000020840.1

UniProt Accession

I3KI95; I3KI95_ORENI

Genbank Protein ID

ENSONIP00000020840

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01002491

Gene Name

src; LOC100692677

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000016547.1	ENSONIT00000020859.1	ENSONIP00000020840.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-12	48.1	89	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ +lydye+ +  +L+++kG+ ++++  ++++++W+ + + ++g +G +P+n+v+ 
   Q: 89   TFVALYDYESRTATDLSFRKGERLQIV--NNTEGDWWLARSLTTGESGYIPSNYVAP 143
           6789***********************..8999*********************975 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MGGSKSKSKD VGQRTRSLDG NLSSGGGAGG HHLNSTQQSL TPNRSPTMDA GLSGNQSMAN 60
TAELTLFGGV DNNSVTSSNC ITRAGGVTTF VALYDYESRT ATDLSFRKGE RLQIVNNTEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAAGTTGG CTCACATCAC AAAACGTAAC ACGCTTCATG TGTCATAGGC TACACAGTCT 60
TAACCGCCAA GAACAGGATG AGTAATTGTA CAACGAACCG CGTTTGAACC TGCACTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0048920--P:posterior lateral line neuromast primordium migration
GO:0043114--P:regulation of vascular permeability
GO:0001878--P:response to yeast

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cpo-021557	Cavia porcellus	81.80	0.00e+00	899.00
IUUC-Dre-028491	Danio rerio	87.20	0.00e+00	949.00
IUUC-Ete-033170	Echinops telfairi	88.65	0.00e+00	845.00
IUUC-Eca-033970	Equus caballus	80.52	0.00e+00	882.00
IUUC-Gac-042332	Gasterosteus aculeatus	92.55	0.00e+00	1016.00
IUUC-Ola-086953	Oryzias latipes	91.90	0.00e+00	967.00
IUUC-Psi-093071	Pelodiscus sinensis	82.59	0.00e+00	916.00
IUUC-Pfo-097229	Poecilia formosa	86.59	0.00e+00	949.00
IUUC-Stu-112331	Solanum tuberosum	32.80	2.00e-23	104.00
IUUC-Tru-117849	Takifugu rubripes	92.46	0.00e+00	977.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence