iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-025940

UUCD1 version

UUC-CiS-00383

Ensembl Protein ID

ENSCSAVP00000006516.1

UniProt Accession

H2YMG4; H2YMG4_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000003903.1	ENSCSAVT00000006599.1	ENSCSAVP00000006516.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-49	169.0	5	151

Active Site

Position(s)	Description	Evidence
119	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 190  veafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPl 276
           v+ freG+ +vi++e+l++F+++e++++i+G    idv+d+k ++ y ggyt+++p+i+ Fw+vl++f++ee+++fL FvT++sr Pl
   Q: 5    VDRFREGLADVISIEWLRMFDHRECQTIISGAqVAIDVDDMKTNAAYSGGYTAEHPTIEIFWRVLHNFTKEEKRKFLLFVTSCSRPPL 92
           789*****************************999***************************************************** PP
   S: 277  gGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
            Gf+e+ p  f+i++ +++drlP+s+TC n+ ++P+Y    ++++kL+y +e+ +gFels
   Q: 93   LGFKEMDPP-FCIHNGGTPDRLPTSSTCLNLVRIPQYIDDITMRDKLIYCVESLAGFELS 151
           *******98.***********************************************985 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

MRVAVDRFRE GLADVISIEW LRMFDHRECQ TIISGAQVAI DVDDMKTNAA YSGGYTAEHP 60
TIEIFWRVLH NFTKEEKRKF LLFVTSCSRP PLLGFKEMDP PFCIHNGGTP DRLPTSSTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATATCTTAT TAAACTGCAA ATCAATTTGT AACAAGATAT TCAATATATA AAAAGGTTCA 60
TAGATATCTT ATATCTACAA GATACATCCA TCTACTATCC AACTACAAAC TCAACATTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dor-030483	Dipodomys ordii	63.45	1.00e-54	207.00
IUUC-Ete-032240	Echinops telfairi	64.65	2.00e-36	146.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence