iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067271

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02045299

Gene Name

RNF149

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007110.2	ENSMLUT00000007111.2	ENSMLUP00000006491.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-07	30.3	210	251

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C e f  kd  ++lpC+H+fh++C+  w         + +CP C+
   Q: 210  CAVCIENFkvKDVIRILPCKHIFHRTCIDPW------LLDHHTCPMCK 251
           ********9988899****************......9999******6 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

RFGDSSPKEG ALGLVGVPGA RDGDPEGCAP DTRFVVPAPG GGGGGGAAPW VALVAHGGCT 60
LKDKVLVAAR RNASAVVIYN EERHGNLTAP LSHAGTGNIV VIMVSYSKGK EILDLVQKEI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTTCGGCG ACAGCTCCCC CAAGGAGGGC GCGCTGGGCC TGGTGGGCGT CCCGGGCGCC 60
CGGGACGGCG ACCCTGAGGG TTGCGCGCCC GACACGCGCT TCGTGGTGCC CGCGCCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF02225--PA
PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0035690--P:cellular response to drug
GO:0043409--P:negative regulation of MAPK cascade
GO:0031647--P:regulation of protein stability

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000637	Aegilops tauschii	38.46	7.00e-13	67.40
IUUC-Aml-001968	Ailuropoda melanoleuca	81.76	3.00e-139	488.00
IUUC-Apl-004109	Anas platyrhynchos	69.02	6.00e-94	336.00
IUUC-Bta-012340	Bos taurus	76.60	7.00e-138	483.00
IUUC-Cja-019566	Callithrix jacchus	74.04	2.00e-130	458.00
IUUC-Cfa-020289	Canis familiaris	81.06	2.00e-95	341.00
IUUC-Cpo-021916	Cavia porcellus	63.22	3.00e-69	254.00
IUUC-Csa-024084	Chlorocebus sabaeus	76.11	1.00e-133	469.00
IUUC-Cho-024305	Choloepus hoffmanni	76.49	2.00e-111	395.00
IUUC-Csv-026229	Ciona savignyi	38.78	6.00e-50	191.00
IUUC-Cgl-026578	Colletotrichum gloeosporioides	48.08	1.00e-12	67.80
IUUC-Cne-026985	Cryptococcus neoformans	30.84	3.00e-11	64.30
IUUC-Dno-030098	Dasypus novemcinctus	76.29	1.00e-135	475.00
IUUC-Dor-030620	Dipodomys ordii	68.39	6.00e-108	384.00
IUUC-Dse-031214	Dothistroma septosporum	50.00	1.00e-11	64.70
IUUC-Ete-032306	Echinops telfairi	78.42	3.00e-140	491.00
IUUC-Fca-035950	Felis catus	76.23	3.00e-102	363.00
IUUC-Fal-037429	Ficedula albicollis	65.17	1.00e-112	399.00
IUUC-Fso-038141	Fusarium solani	43.48	8.00e-15	75.10
IUUC-Gga-041201	Gallus gallus	64.43	5.00e-113	400.00
IUUC-Ggo-045429	Gorilla gorilla	75.81	4.00e-132	464.00
IUUC-Hsa-046191	Homo sapiens	76.40	9.00e-131	459.00
IUUC-Itr-048018	Ictidomys tridecemlineatus	76.97	2.00e-123	435.00
IUUC-Lch-049498	Latimeria chalumnae	59.59	9.00e-108	383.00
IUUC-Laf-054239	Loxodonta africana	67.88	3.00e-111	394.00
IUUC-Meu-056382	Macropus eugenii	67.78	9.00e-118	416.00
IUUC-Mga-059435	Meleagris gallopavo	66.67	2.00e-61	228.00
IUUC-Mmr-061513	Microcebus murinus	75.38	8.00e-133	466.00
IUUC-Mdo-063028	Monodelphis domestica	69.91	2.00e-123	435.00
IUUC-Mmu-063545	Mus musculus	69.91	1.00e-116	412.00
IUUC-Mpu-066370	Mustela putorius furo	88.48	4.00e-135	474.00
IUUC-Nle-069207	Nomascus leucogenys	75.52	4.00e-131	461.00
IUUC-Opr-070704	Ochotona princeps	65.31	9.00e-82	296.00
IUUC-Oan-072837	Ornithorhynchus anatinus	67.80	3.00e-115	408.00
IUUC-Ocu-074671	Oryctolagus cuniculus	73.26	8.00e-108	383.00
IUUC-Oga-089083	Otolemur garnettii	72.30	4.00e-134	471.00
IUUC-Oar-089254	Ovis aries	78.30	2.00e-99	354.00
IUUC-Ptr-090940	Pan troglodytes	76.11	5.00e-132	464.00
IUUC-Pan-092636	Papio anubis	75.22	2.00e-132	465.00
IUUC-Psi-093435	Pelodiscus sinensis	70.93	7.00e-86	310.00
IUUC-Pab-098525	Pongo abelii	76.90	1.00e-130	459.00
IUUC-Pva-102395	Pteropus vampyrus	78.47	4.00e-141	494.00
IUUC-Pgr-103263	Puccinia graminis	39.24	1.00e-10	61.60
IUUC-Rno-105789	Rattus norvegicus	72.06	6.00e-118	417.00
IUUC-Sha-107305	Sarcophilus harrisii	67.65	3.00e-83	301.00
IUUC-Ssc-115598	Sus scrofa	74.05	1.00e-132	466.00
IUUC-Tgu-116463	Taeniopygia guttata	65.17	2.00e-112	398.00
IUUC-Tsy-118915	Tarsius syrichta	75.72	1.00e-92	332.00
IUUC-Tre-121978	Trichoderma reesei	51.02	6.00e-13	68.90
IUUC-Tme-126970	Tuber melanosporum	49.06	6.00e-13	68.90
IUUC-Tbe-127906	Tupaia belangeri	58.37	1.00e-64	239.00
IUUC-Xtr-131821	Xenopus tropicalis	60.84	2.00e-107	382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence