iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034237

UUCD1 version

UUC-EqC-00483

Ensembl Protein ID

ENSECAP00000019077.1

UniProt Accession

F6XWF4; F6XWF4_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021523.1	ENSECAT00000023050.1	ENSECAP00000019077.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.60e-18	66.3	39	104
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-11	43.5	138	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+++v+g ef+ahk +L+++Ss+F+alf++++++++ k+ ++i +++p+ ++ ++++ Yt ++++
   Q: 39   CDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTE-KKVYNIPGISPDMMKLIIEYAYTRTVPI 104
           8**********************************998.***********************99986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l+Nc+gi+ f d y cp+L+++a +fil++F+
   Q: 138  LDNCIGICKFTDYYYCPELRQKAYMFILHNFE 169
           69*****************************5 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MEMESAAAST RFHQPHMERK MSAMTCEIFN ELRLEGKLCD VVIKVNGFEF NAHKNILCSC 60
SSYFRALFTS GWNNTEKKVY NIPGISPDMM KLIIEYAYTR TVPITPDNVE KLLAAADQFN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATTCTGG AACTTGGGCT GCCTGATGGG CCCTATATGA AAGATGTAGT AGGGAAAAGG 60
AGCGACAGCT GGCTAAAGGG GCCCCCCCAC AACCCTCCCC CATCACCCTA GGAGAGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0000902--P:cell morphogenesis
GO:0009566--P:fertilization
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0048808--P:male genitalia morphogenesis
GO:0008584--P:male gonad development
GO:0016567--P:protein ubiquitination
GO:0007286--P:spermatid development

KEGG

ecb:100053248

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001576	Ailuropoda melanoleuca	99.84	0.00e+00	1274.00
IUUC-Apl-003525	Anas platyrhynchos	82.49	0.00e+00	1052.00
IUUC-Aca-005295	Anolis carolinensis	88.32	0.00e+00	956.00
IUUC-Ang-009879	Aspergillus niger	26.92	9.00e-09	54.30
IUUC-Ame-010953	Astyanax mexicanus	48.25	1.00e-164	572.00
IUUC-Bta-013447	Bos taurus	99.84	0.00e+00	1274.00
IUUC-Cja-019472	Callithrix jacchus	98.95	0.00e+00	791.00
IUUC-Cfa-020332	Canis familiaris	99.67	0.00e+00	1273.00
IUUC-Cpo-021949	Cavia porcellus	98.19	0.00e+00	1255.00
IUUC-Csa-023573	Chlorocebus sabaeus	99.34	0.00e+00	1269.00
IUUC-Cho-024451	Choloepus hoffmanni	98.34	0.00e+00	1097.00
IUUC-Cin-025680	Ciona intestinalis	51.68	6.00e-173	600.00
IUUC-Csv-026085	Ciona savignyi	51.15	2.00e-172	598.00
IUUC-Dre-028188	Danio rerio	57.31	0.00e+00	690.00
IUUC-Dno-029608	Dasypus novemcinctus	99.84	0.00e+00	1275.00
IUUC-Dor-030200	Dipodomys ordii	100.00	0.00e+00	1140.00
IUUC-Dme-031964	Drosophila melanogaster	46.56	2.00e-153	536.00
IUUC-Ete-032475	Echinops telfairi	96.05	0.00e+00	1221.00
IUUC-Eeu-035104	Erinaceus europaeus	88.99	7.00e-168	582.00
IUUC-Fca-036271	Felis catus	99.67	0.00e+00	1274.00
IUUC-Fal-037352	Ficedula albicollis	68.41	0.00e+00	852.00
IUUC-Ggr-040046	Gaeumannomyces graminis	29.73	4.00e-07	49.70
IUUC-Gga-040205	Gallus gallus	80.14	0.00e+00	1017.00
IUUC-Gac-041982	Gasterosteus aculeatus	54.20	0.00e+00	642.00
IUUC-Ggo-045241	Gorilla gorilla	99.01	0.00e+00	1265.00
IUUC-Hsa-047022	Homo sapiens	99.01	0.00e+00	1265.00
IUUC-Itr-048079	Ictidomys tridecemlineatus	99.84	0.00e+00	1274.00
IUUC-Lch-050637	Latimeria chalumnae	86.96	0.00e+00	1136.00
IUUC-Loc-052412	Lepisosteus oculatus	75.04	0.00e+00	962.00
IUUC-Laf-054118	Loxodonta africana	99.67	0.00e+00	1273.00
IUUC-Mcc-055476	Macaca mulatta	91.28	0.00e+00	1141.00
IUUC-Meu-056158	Macropus eugenii	99.84	0.00e+00	1274.00
IUUC-Mpo-057379	Magnaporthe poae	32.88	3.00e-07	48.90
IUUC-Mga-059634	Meleagris gallopavo	81.05	0.00e+00	1007.00
IUUC-Mmr-061217	Microcebus murinus	90.46	0.00e+00	1125.00
IUUC-Mdo-062138	Monodelphis domestica	99.84	0.00e+00	1273.00
IUUC-Mmu-063769	Mus musculus	99.84	0.00e+00	1274.00
IUUC-Mpu-066045	Mustela putorius furo	100.00	0.00e+00	1275.00
IUUC-Mlu-067348	Myotis lucifugus	99.34	0.00e+00	1269.00
IUUC-Nfi-068435	Neosartorya fischeri	30.65	7.00e-07	47.00
IUUC-Nle-069331	Nomascus leucogenys	98.68	0.00e+00	1259.00
IUUC-Opr-071203	Ochotona princeps	97.04	0.00e+00	1229.00
IUUC-Ont-071882	Oreochromis niloticus	49.49	1.00e-158	553.00
IUUC-Ocu-073757	Oryctolagus cuniculus	99.67	0.00e+00	1268.00
IUUC-Ola-086791	Oryzias latipes	49.08	3.00e-152	531.00
IUUC-Oga-088676	Otolemur garnettii	99.34	0.00e+00	1272.00
IUUC-Oar-089804	Ovis aries	99.67	0.00e+00	1271.00
IUUC-Ptr-090767	Pan troglodytes	98.68	0.00e+00	1261.00
IUUC-Pan-092856	Papio anubis	99.34	0.00e+00	1269.00
IUUC-Psi-094041	Pelodiscus sinensis	92.59	0.00e+00	1201.00
IUUC-Pfo-096673	Poecilia formosa	58.17	0.00e+00	664.00
IUUC-Pab-097694	Pongo abelii	98.68	0.00e+00	1261.00
IUUC-Pca-100693	Procavia capensis	92.27	0.00e+00	997.00
IUUC-Pva-102153	Pteropus vampyrus	100.00	0.00e+00	846.00
IUUC-Rno-105012	Rattus norvegicus	99.84	0.00e+00	1275.00
IUUC-Sha-106593	Sarcophilus harrisii	99.84	0.00e+00	1275.00
IUUC-Sar-113188	Sorex araneus	98.98	0.00e+00	1202.00
IUUC-Tgu-116852	Taeniopygia guttata	70.60	0.00e+00	843.00
IUUC-Tru-118098	Takifugu rubripes	48.82	4.00e-161	561.00
IUUC-Tsy-119581	Tarsius syrichta	85.69	0.00e+00	1062.00
IUUC-Tni-120002	Tetraodon nigroviridis	51.85	4.00e-163	567.00
IUUC-Tbe-127778	Tupaia belangeri	92.60	0.00e+00	1156.00
IUUC-Ttr-128966	Tursiops truncatus	92.93	0.00e+00	1163.00
IUUC-Vpa-130421	Vicugna pacos	99.74	0.00e+00	799.00
IUUC-Xtr-131853	Xenopus tropicalis	59.13	0.00e+00	685.00
IUUC-Xma-133112	Xiphophorus maculatus	58.53	0.00e+00	667.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence