iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022221

Ensembl Protein ID

ENSCPOP00000012388.2

UniProt Accession

H0VPG6; H0VPG6_CAVPO

Genbank Protein ID

ENSCPOP00000012388

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02055351

Gene Name

KDM5A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000013751.3	ENSCPOT00000013891.2	ENSCPOP00000012388.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-09	37.7	675	729

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClkls.......veeelpnsekwiCpkCr 52
           k+C +C+++ ++   +++Ce C++wfH +C+ l+        ++ + ++ k+ Cp C 
   Q: 675  KFC-ICRKTASGF--MLQCELCKDWFHNNCVPLPksssqkkGSSWQAKEVKFLCPLCM 729
           68*.*******87..******************9777776656666666669999996 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

WSYSINYLHW GEPKTWYGVP SHAAEQLEEV MRELAPELFE SQPDLLHQLV TIMNPNVLME 60
HGVPVYRTNQ CAGEFVVTFP RAYHSGFNQG YNFAEAVNFC TADWLPIGRQ CVNHYRRLRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAGTTACT CCATTAACTA CTTGCATTGG TATGTATGTA TTGTATTGGT ATGTATCCTT 60
GATCAGTACG GCATACAGAG TTACTGAACT GTTTGTTTAT TTTAGTGCTG AGGGTTGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0019907--C:cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0032993--C:protein-DNA complex
GO:0031490--F:chromatin DNA binding
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0032922--P:circadian regulation of gene expression
GO:0034720--P:histone H3-K4 demethylation
GO:1901726--P:negative regulation of histone deacetylase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002061	Ailuropoda melanoleuca	97.59	0.00e+00	2012.00
IUUC-Apl-004141	Anas platyrhynchos	92.45	0.00e+00	1986.00
IUUC-Aca-004952	Anolis carolinensis	91.14	0.00e+00	1978.00
IUUC-Ame-011323	Astyanax mexicanus	76.37	0.00e+00	1630.00
IUUC-Bta-012902	Bos taurus	96.43	0.00e+00	2022.00
IUUC-Cja-018988	Callithrix jacchus	95.14	0.00e+00	2043.00
IUUC-Cfa-020212	Canis familiaris	96.09	0.00e+00	1972.00
IUUC-Csa-023575	Chlorocebus sabaeus	98.24	0.00e+00	1904.00
IUUC-Cho-024280	Choloepus hoffmanni	89.78	0.00e+00	1770.00
IUUC-Dre-027909	Danio rerio	73.82	0.00e+00	1248.00
IUUC-Dno-029473	Dasypus novemcinctus	97.18	0.00e+00	1877.00
IUUC-Dor-030281	Dipodomys ordii	95.45	0.00e+00	1234.00
IUUC-Ete-033144	Echinops telfairi	89.50	0.00e+00	847.00
IUUC-Eca-034265	Equus caballus	97.09	0.00e+00	2043.00
IUUC-Fca-035476	Felis catus	96.43	0.00e+00	2006.00
IUUC-Fal-037078	Ficedula albicollis	92.66	0.00e+00	1606.00
IUUC-Gga-040466	Gallus gallus	91.22	0.00e+00	1970.00
IUUC-Gac-042566	Gasterosteus aculeatus	77.23	0.00e+00	1410.00
IUUC-Ggo-044524	Gorilla gorilla	89.29	0.00e+00	1769.00
IUUC-Hsa-045821	Homo sapiens	97.84	0.00e+00	2022.00
IUUC-Itr-048908	Ictidomys tridecemlineatus	96.27	0.00e+00	1122.00
IUUC-Lch-050630	Latimeria chalumnae	76.43	0.00e+00	1406.00
IUUC-Loc-051963	Lepisosteus oculatus	80.83	0.00e+00	1441.00
IUUC-Laf-053918	Loxodonta africana	87.89	0.00e+00	1614.00
IUUC-Mcc-055672	Macaca mulatta	95.84	0.00e+00	2003.00
IUUC-Meu-056374	Macropus eugenii	83.10	0.00e+00	961.00
IUUC-Mga-059192	Meleagris gallopavo	80.40	0.00e+00	1615.00
IUUC-Mmr-060968	Microcebus murinus	95.11	0.00e+00	2034.00
IUUC-Mdo-062945	Monodelphis domestica	95.34	0.00e+00	1849.00
IUUC-Mmu-063614	Mus musculus	96.34	0.00e+00	1997.00
IUUC-Mpu-066349	Mustela putorius furo	97.74	0.00e+00	1894.00
IUUC-Mlu-067363	Myotis lucifugus	96.92	0.00e+00	2067.00
IUUC-Nle-070142	Nomascus leucogenys	97.76	0.00e+00	2029.00
IUUC-Opr-071002	Ochotona princeps	90.53	0.00e+00	1397.00
IUUC-Ont-072471	Oreochromis niloticus	77.87	0.00e+00	1448.00
IUUC-Oan-072797	Ornithorhynchus anatinus	79.41	0.00e+00	1207.00
IUUC-Ocu-074164	Oryctolagus cuniculus	95.27	0.00e+00	2068.00
IUUC-Ola-087076	Oryzias latipes	76.52	0.00e+00	1394.00
IUUC-Oga-088350	Otolemur garnettii	97.51	0.00e+00	2045.00
IUUC-Oar-090045	Ovis aries	96.43	0.00e+00	2026.00
IUUC-Ptr-091199	Pan troglodytes	97.01	0.00e+00	2006.00
IUUC-Pan-092094	Papio anubis	93.85	0.00e+00	1992.00
IUUC-Psi-093550	Pelodiscus sinensis	92.16	0.00e+00	1737.00
IUUC-Pfo-097266	Poecilia formosa	77.54	0.00e+00	1420.00
IUUC-Pab-098576	Pongo abelii	97.84	0.00e+00	2015.00
IUUC-Pca-100123	Procavia capensis	93.63	0.00e+00	1655.00
IUUC-Pva-103109	Pteropus vampyrus	91.52	0.00e+00	1924.00
IUUC-Rno-105664	Rattus norvegicus	96.26	0.00e+00	1990.00
IUUC-Sha-107506	Sarcophilus harrisii	94.60	0.00e+00	1989.00
IUUC-Sja-107734	Schizosaccharomyces japonicus	21.51	1.00e-30	129.00
IUUC-Spo-108246	Schizosaccharomyces pombe	21.58	1.00e-34	142.00
IUUC-Sar-113052	Sorex araneus	96.18	0.00e+00	2012.00
IUUC-Tgu-116613	Taeniopygia guttata	91.12	0.00e+00	1925.00
IUUC-Tru-118604	Takifugu rubripes	76.73	0.00e+00	1471.00
IUUC-Tsy-119237	Tarsius syrichta	97.45	0.00e+00	1313.00
IUUC-Tni-120779	Tetraodon nigroviridis	76.50	0.00e+00	1440.00
IUUC-Tbe-127627	Tupaia belangeri	98.33	0.00e+00	726.00
IUUC-Ttr-129242	Tursiops truncatus	94.01	0.00e+00	1911.00
IUUC-Xtr-131762	Xenopus tropicalis	83.59	0.00e+00	1745.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence