iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-007217

UUCD1 version

UUC-ArT-01648

Ensembl Protein ID

AT3G15355.1

UniProt Accession

Q9LUQ5; Q4TYY6; Q9M7X2; UBC25_ARATH

Genbank Protein ID

BAB02364.1; BAB02364.1; AAF35401.1; AEE75657.1; AAK32819.1; AAL15380.1; AAY44864.1

Protein Name

Probable ubiquitin-conjugating enzyme E2 25; E2 ubiquitin-conjugating enzyme 25; Ubiquitin carrier protein 25

Genbank Nucleotide ID

AB022218; AP000413; AC024081; CP002686; AF361806; AY059155; DQ027038

Gene Name

UBC25; At3g15355; MJK13.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT3G15355	AT3G15355.1	AT3G15355.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.70e-27	96.7	336	469

Active Site

Position(s)	Description	Evidence
418	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk..ifhPnvyenGkvClsilk.....eeek 91
           R++ e   lekd pe i+++  ++  ++ ++++i+G ++tpY++g+F ++i fp++YP++PP v++ +   + +Pn+y+ GkvCls+l+     ++ek
   Q: 336  RIQDEWRILEKDLPEMIFVRAYES-RMDLLRAVIIGAQGTPYHDGLFFFDIFFPDTYPSTPPIVHYHSGglRINPNLYNCGKVCLSLLGtwsgnQREK 432
           899*********************.5******************************************9999****************66677799** PP
   S: 92   Wsp.alsvesvllsiqsll..aepnpesplneeaael 125
           W p ++++ +vl+siq l+  ++p++++p +e++a  
   Q: 433  WIPnTSTMLQVLVSIQGLIlnQKPYFNEPGYERSAGS 469
           ***8889***********99888*******9998833 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.

Protein Sequence
(Fasta)

MEPNVVEIAT PPAASCSRIR TPTKAETPEV IDVEEYDLQN GGVPNGNNVD YKNKGKAIDF 60
DSMSYGDYGE EDEYAVGSPG DDYGYPESSP LSNSLLDPES LIYEDDENYS EQYDFEMEAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCACTGTTTT AATTTAGGTC TTTAATTTAT TAAGATTTAG GATTAATAGA GAGAAAGAGG 60
AATTGGTTTT AAGTGTTAAG AGAGAAAAGC CTTTGCGCAA TCTCACTGTG TGTTGGTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding

KEGG

ath:AT3G15355

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001583	Ailuropoda melanoleuca	45.76	2.00e-35	146.00
IUUC-Aly-005551	Arabidopsis lyrata	82.93	0.00e+00	880.00
IUUC-Afl-008480	Aspergillus flavus	46.27	2.00e-45	177.00
IUUC-Ani-009341	Aspergillus nidulans	35.68	6.00e-32	132.00
IUUC-Ate-010487	Aspergillus terreus	45.27	3.00e-46	180.00
IUUC-Ame-011337	Astyanax mexicanus	45.20	9.00e-35	144.00
IUUC-Bta-012501	Bos taurus	45.76	2.00e-35	145.00
IUUC-Bdi-014931	Brachypodium distachyon	60.51	5.00e-95	340.00
IUUC-Bol-016151	Brassica oleracea	61.94	0.00e+00	628.00
IUUC-Bra-017244	Brassica rapa	63.98	1.00e-175	608.00
IUUC-Cel-018661	Caenorhabditis elegans	42.51	1.00e-39	157.00
IUUC-Cja-018746	Callithrix jacchus	46.33	7.00e-36	147.00
IUUC-Cfa-020170	Canis familiaris	45.76	2.00e-35	146.00
IUUC-Cpo-022138	Cavia porcellus	45.76	2.00e-35	145.00
IUUC-Cre-022768	Chlamydomonas reinhardtii	47.95	7.00e-37	146.00
IUUC-Csa-023927	Chlorocebus sabaeus	45.76	2.00e-35	145.00
IUUC-Cne-026812	Cryptococcus neoformans	46.08	7.00e-49	188.00
IUUC-Dre-027941	Danio rerio	46.33	8.00e-44	174.00
IUUC-Dno-028913	Dasypus novemcinctus	45.20	8.00e-35	144.00
IUUC-Ete-032587	Echinops telfairi	43.75	3.00e-32	135.00
IUUC-Eca-033819	Equus caballus	45.20	2.00e-33	139.00
IUUC-Fca-035505	Felis catus	45.76	3.00e-35	145.00
IUUC-Gmo-039521	Gadus morhua	45.76	1.00e-35	144.00
IUUC-Ggr-040040	Gaeumannomyces graminis	45.62	1.00e-31	131.00
IUUC-Gac-042251	Gasterosteus aculeatus	40.17	2.00e-37	150.00
IUUC-Gma-044076	Glycine max	61.73	6.00e-104	371.00
IUUC-Hsa-046339	Homo sapiens	45.76	3.00e-35	145.00
IUUC-Hvu-047441	Hordeum vulgare	61.71	3.00e-96	344.00
IUUC-Lpe-051294	Leersia perrieri	60.87	5.00e-95	340.00
IUUC-Loc-052800	Lepisosteus oculatus	45.76	2.00e-35	145.00
IUUC-Laf-054034	Loxodonta africana	45.76	2.00e-35	145.00
IUUC-Mcc-055267	Macaca mulatta	45.76	2.00e-35	145.00
IUUC-Mpo-057396	Magnaporthe poae	50.33	6.00e-34	139.00
IUUC-Mmr-061179	Microcebus murinus	45.76	3.00e-35	145.00
IUUC-Mdo-062990	Monodelphis domestica	45.76	3.00e-35	145.00
IUUC-Mmu-063825	Mus musculus	45.76	4.00e-35	145.00
IUUC-Mpu-065908	Mustela putorius furo	45.76	2.00e-35	146.00
IUUC-Mlu-067106	Myotis lucifugus	45.76	3.00e-35	145.00
IUUC-Nle-069347	Nomascus leucogenys	45.76	2.00e-35	145.00
IUUC-Opr-070799	Ochotona princeps	45.76	3.00e-35	145.00
IUUC-Ont-072046	Oreochromis niloticus	38.22	1.00e-35	147.00
IUUC-Ocu-074556	Oryctolagus cuniculus	45.76	2.00e-35	145.00
IUUC-Oba-075602	Oryza barthii	58.70	4.00e-86	311.00
IUUC-Obr-076463	Oryza brachyantha	59.71	1.00e-94	338.00
IUUC-Ogl-077040	Oryza glaberrima	58.70	4.00e-86	311.00
IUUC-Ogu-078917	Oryza glumaepatula	58.70	4.00e-86	311.00
IUUC-Oin-079561	Oryza indica	58.70	4.00e-86	311.00
IUUC-Ome-081384	Oryza meridionalis	58.70	7.00e-86	310.00
IUUC-Oni-082241	Oryza nivara	58.70	4.00e-86	311.00
IUUC-Opu-083659	Oryza punctata	59.06	1.00e-93	336.00
IUUC-Oru-084622	Oryza rufipogon	58.70	5.00e-86	311.00
IUUC-Osa-085920	Oryza sativa	58.70	5.00e-86	311.00
IUUC-Ola-087459	Oryzias latipes	45.76	4.00e-36	147.00
IUUC-Oar-090367	Ovis aries	45.76	2.00e-35	146.00
IUUC-Ptr-091512	Pan troglodytes	45.76	3.00e-35	145.00
IUUC-Pan-092222	Papio anubis	45.76	2.00e-35	145.00
IUUC-Pab-098390	Pongo abelii	45.76	3.00e-35	145.00
IUUC-Pop-099782	Populus trichocarpa	44.46	2.00e-119	422.00
IUUC-Pva-103053	Pteropus vampyrus	45.76	2.00e-35	146.00
IUUC-Pte-104333	Pyrenophora teres	40.00	2.00e-38	154.00
IUUC-Pyt-104498	Pyrenophora triticirepentis	38.70	9.00e-37	148.00
IUUC-Sha-107483	Sarcophilus harrisii	45.76	3.00e-35	145.00
IUUC-Sit-110473	Setaria italica	60.82	2.00e-87	315.00
IUUC-Ssc-115927	Sus scrofa	45.76	3.00e-35	145.00
IUUC-Tgu-117132	Taeniopygia guttata	41.01	2.00e-33	139.00
IUUC-Tru-118115	Takifugu rubripes	37.80	1.00e-35	147.00
IUUC-Tsy-118899	Tarsius syrichta	50.00	3.00e-32	135.00
IUUC-Tni-120891	Tetraodon nigroviridis	39.33	2.00e-35	146.00
IUUC-Tca-121636	Theobroma cacao	42.41	2.00e-119	422.00
IUUC-Vpa-130310	Vicugna pacos	45.76	2.00e-35	145.00
IUUC-Vvi-131664	Vitis vinifera	62.86	1.00e-96	346.00
IUUC-Xtr-131861	Xenopus tropicalis	45.20	5.00e-42	168.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence