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Tag Content
UUCD2 ID IUUC-Mcc-055684
UUCD1 version UUC-MaM-00474
Ensembl Protein ID ENSMMUP00000028200.3
UniProt Accession H9ET39; F7EJ69; H9ET39_MACMU
Genbank Protein ID AFE65548.1; AFH29900.1; AFI33987.1
Protein Name TNF receptor-associated factor 4
Genbank Nucleotide ID JSUE03016318; JU473096; JV043916
Gene Name TRAF4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000021407.3 ENSMMUT00000030133.3 ENSMMUP00000028200.3
ENSMMUG00000021407.3 ENSMMUT00000023821.3 ENSMMUP00000022296.3
ENSMMUG00000021407.3 ENSMMUT00000030134.3 ENSMMUP00000028201.3
ENSMMUG00000021407.3 ENSMMUT00000073207.1 ENSMMUP00000044534.1
ENSMMUG00000021407.3 ENSMMUT00000056564.1 ENSMMUP00000055558.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 5.10e-06 28.0 18 56
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKIYPDP ELEVQVLGLP IRCIHSEEGC RWNGPLRHLQ GHLNTCSFNV VPCPNRCPMK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055684|E3,RING|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGAGGCGCG GGCTGTGGGG CCGCCGCGTG CCTGGCCCCG CTCGCCCGTG CCGGCCGCTC 60
GCCCGCCATG CCTGGTTTCG ACTACAAGTT CCTGGAGAAG CCCAAGCGAC GGCTGCTGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055684|E3,RING|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF
PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF
Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF
SMART

SM00061--MATH
SM00184--RING
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process
GO:0007585--P:respiratory gaseous exchange
GO:0030323--P:respiratory tube development
KEGG mcc:716364
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000797 Aegilops tauschii 40.51 3.00e-08 53.10
IUUC-Aml-001287 Ailuropoda melanoleuca 96.38 0.00e+00 899.00
IUUC-Ame-011530 Astyanax mexicanus 77.45 0.00e+00 774.00
IUUC-Bta-013582 Bos taurus 98.72 0.00e+00 924.00
IUUC-Cja-019883 Callithrix jacchus 94.79 1.00e-51 194.00
IUUC-Cfa-020133 Canis familiaris 91.70 0.00e+00 850.00
IUUC-Cpo-022021 Cavia porcellus 98.72 0.00e+00 928.00
IUUC-Csa-023199 Chlorocebus sabaeus 100.00 0.00e+00 937.00
IUUC-Dre-028193 Danio rerio 76.60 0.00e+00 769.00
IUUC-Dno-028917 Dasypus novemcinctus 98.72 0.00e+00 927.00
IUUC-Ete-032433 Echinops telfairi 97.45 0.00e+00 915.00
IUUC-Fca-036155 Felis catus 97.87 0.00e+00 922.00
IUUC-Gmo-038860 Gadus morhua 77.45 0.00e+00 772.00
IUUC-Gga-041052 Gallus gallus 80.85 0.00e+00 827.00
IUUC-Gac-041489 Gasterosteus aculeatus 77.23 0.00e+00 770.00
IUUC-Gma-042951 Glycine max 26.77 8.00e-08 51.60
IUUC-Ggo-044996 Gorilla gorilla 98.94 0.00e+00 928.00
IUUC-Hsa-046252 Homo sapiens 99.15 0.00e+00 931.00
IUUC-Itr-048232 Ictidomys tridecemlineatus 99.15 0.00e+00 930.00
IUUC-Kpa-049340 Komagataella pastoris 26.46 1.00e-15 78.20
IUUC-Lpe-051100 Leersia perrieri 38.57 1.00e-07 50.80
IUUC-Loc-052312 Lepisosteus oculatus 77.07 0.00e+00 767.00
IUUC-Laf-054376 Loxodonta africana 98.72 0.00e+00 926.00
IUUC-Mmr-061198 Microcebus murinus 99.15 0.00e+00 929.00
IUUC-Mdo-062585 Monodelphis domestica 87.45 0.00e+00 833.00
IUUC-Mmu-064303 Mus musculus 97.23 0.00e+00 917.00
IUUC-Mac-064529 Musa acuminata 30.40 2.00e-10 60.10
IUUC-Mpu-066854 Mustela putorius furo 97.45 0.00e+00 918.00
IUUC-Nle-070098 Nomascus leucogenys 97.87 0.00e+00 919.00
IUUC-Ont-071518 Oreochromis niloticus 77.40 0.00e+00 771.00
IUUC-Ocu-073841 Oryctolagus cuniculus 98.94 0.00e+00 929.00
IUUC-Ola-086674 Oryzias latipes 77.19 0.00e+00 769.00
IUUC-Oga-088510 Otolemur garnettii 98.72 0.00e+00 927.00
IUUC-Oar-089225 Ovis aries 94.89 0.00e+00 881.00
IUUC-Pan-092725 Papio anubis 100.00 0.00e+00 937.00
IUUC-Pfo-096341 Poecilia formosa 77.19 0.00e+00 772.00
IUUC-Pva-103131 Pteropus vampyrus 99.24 1.00e-143 502.00
IUUC-Rno-105996 Rattus norvegicus 97.45 0.00e+00 918.00
IUUC-Sly-111800 Solanum lycopersicum 30.00 6.00e-06 47.40
IUUC-Tru-117602 Takifugu rubripes 77.45 0.00e+00 775.00
IUUC-Tur-126067 Triticum urartu 40.51 2.00e-08 53.50
Created Date 25-Jun-2017

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