iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073128

Ensembl Protein ID

ENSOANP00000001701.3

UniProt Accession

F6YGK3; F6YGK3_ORNAN

Genbank Protein ID

ENSOANP00000001701

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPN01156869

Gene Name

LATS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000001067.3	ENSOANT00000001702.3	ENSOANP00000001701.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	86.87	0.00e+00	1594.00	IUUC-Hsa-046081
UBD/Alpha-Helix/UBA	85.25	0.00e+00	1571.00	IUUC-Mmu-063504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MVIRALRQTN NRSIEAAIEF ISKMSYQDPR REQMAAAAAR PVNAGLKPPG GVQQSVNRKQ 60
SWKGSKESLV PQRLGPQLGE NAVYRSESPN PQTDVGRPLS GSGLTAFAQG HPCNGQRVNP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTTAAAAA TTCTCCTTTT AGGAAATGGT TATACGAGCT CTTCGACAGA CTAACAATAG 60
AAGTATAGAG GCAGCAATTG AATTTATTAG TAAAATGAGT TACCAAGATC CTCGTCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0060644--P:mammary gland epithelial cell differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:0046620--P:regulation of organ growth
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	86.32	0.00e+00	1609.00
IUUC-Apl-003278	Anas platyrhynchos	83.84	0.00e+00	1547.00
IUUC-Aca-005319	Anolis carolinensis	81.33	0.00e+00	1494.00
IUUC-Ame-011324	Astyanax mexicanus	88.13	0.00e+00	927.00
IUUC-Bta-013438	Bos taurus	85.61	0.00e+00	1570.00
IUUC-Cel-018517	Caenorhabditis elegans	49.68	8.00e-127	447.00
IUUC-Cja-019072	Callithrix jacchus	86.32	0.00e+00	1617.00
IUUC-Cfa-021267	Canis familiaris	86.32	0.00e+00	1612.00
IUUC-Cpo-021496	Cavia porcellus	82.01	0.00e+00	1306.00
IUUC-Csa-023255	Chlorocebus sabaeus	86.32	0.00e+00	1597.00
IUUC-Cho-024461	Choloepus hoffmanni	94.64	0.00e+00	761.00
IUUC-Cin-025264	Ciona intestinalis	65.58	1.00e-140	492.00
IUUC-Dre-028034	Danio rerio	84.31	0.00e+00	914.00
IUUC-Dno-029888	Dasypus novemcinctus	84.80	0.00e+00	1612.00
IUUC-Dor-030144	Dipodomys ordii	79.22	0.00e+00	1337.00
IUUC-Dme-031656	Drosophila melanogaster	74.46	0.00e+00	653.00
IUUC-Ete-032813	Echinops telfairi	89.89	0.00e+00	1153.00
IUUC-Eca-033781	Equus caballus	85.61	0.00e+00	1576.00
IUUC-Eeu-035007	Erinaceus europaeus	83.91	0.00e+00	1569.00
IUUC-Fca-036142	Felis catus	88.96	0.00e+00	1347.00
IUUC-Fal-036626	Ficedula albicollis	83.84	0.00e+00	1564.00
IUUC-Gmo-038688	Gadus morhua	85.75	0.00e+00	772.00
IUUC-Gga-040553	Gallus gallus	83.59	0.00e+00	1548.00
IUUC-Gac-042031	Gasterosteus aculeatus	66.14	0.00e+00	1134.00
IUUC-Ggo-045242	Gorilla gorilla	86.43	0.00e+00	1602.00
IUUC-Hsa-046081	Homo sapiens	86.42	0.00e+00	1600.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	86.36	0.00e+00	1539.00
IUUC-Lch-049425	Latimeria chalumnae	78.66	0.00e+00	1442.00
IUUC-Loc-052418	Lepisosteus oculatus	68.79	0.00e+00	1165.00
IUUC-Laf-053710	Loxodonta africana	85.05	0.00e+00	1591.00
IUUC-Mcc-055079	Macaca mulatta	86.12	0.00e+00	1595.00
IUUC-Meu-056509	Macropus eugenii	69.38	0.00e+00	629.00
IUUC-Mga-059713	Meleagris gallopavo	83.12	0.00e+00	1545.00
IUUC-Mmr-061728	Microcebus murinus	85.78	0.00e+00	1610.00
IUUC-Mdo-061942	Monodelphis domestica	85.17	0.00e+00	1583.00
IUUC-Mmu-063504	Mus musculus	84.91	0.00e+00	1561.00
IUUC-Mpu-066034	Mustela putorius furo	86.12	0.00e+00	1589.00
IUUC-Mlu-067986	Myotis lucifugus	85.71	0.00e+00	1592.00
IUUC-Nle-069202	Nomascus leucogenys	86.12	0.00e+00	1594.00
IUUC-Opr-070801	Ochotona princeps	90.71	0.00e+00	1196.00
IUUC-Ont-072487	Oreochromis niloticus	62.20	0.00e+00	1119.00
IUUC-Ocu-073998	Oryctolagus cuniculus	88.89	0.00e+00	1331.00
IUUC-Ola-086858	Oryzias latipes	61.42	0.00e+00	1063.00
IUUC-Oga-088874	Otolemur garnettii	84.32	0.00e+00	1553.00
IUUC-Oar-089236	Ovis aries	85.43	0.00e+00	1569.00
IUUC-Ptr-091425	Pan troglodytes	86.52	0.00e+00	1603.00
IUUC-Pan-091851	Papio anubis	86.23	0.00e+00	1597.00
IUUC-Psi-093825	Pelodiscus sinensis	83.59	0.00e+00	1263.00
IUUC-Pfo-096326	Poecilia formosa	61.20	0.00e+00	1075.00
IUUC-Pab-097815	Pongo abelii	86.42	0.00e+00	1601.00
IUUC-Pca-101081	Procavia capensis	62.88	0.00e+00	883.00
IUUC-Pva-102836	Pteropus vampyrus	85.01	0.00e+00	1514.00
IUUC-Ptt-103762	Puccinia triticina	37.73	3.00e-92	332.00
IUUC-Rno-106053	Rattus norvegicus	85.21	0.00e+00	1579.00
IUUC-Sha-106843	Sarcophilus harrisii	86.23	0.00e+00	1623.00
IUUC-Sar-113649	Sorex araneus	85.60	0.00e+00	1385.00
IUUC-Ssc-115486	Sus scrofa	93.10	0.00e+00	823.00
IUUC-Tgu-116903	Taeniopygia guttata	83.33	0.00e+00	1551.00
IUUC-Tru-118760	Takifugu rubripes	64.52	0.00e+00	1156.00
IUUC-Tsy-119361	Tarsius syrichta	85.21	0.00e+00	1535.00
IUUC-Tni-120058	Tetraodon nigroviridis	61.97	0.00e+00	1043.00
IUUC-Tbe-127681	Tupaia belangeri	87.72	0.00e+00	1394.00
IUUC-Ttr-128652	Tursiops truncatus	84.66	0.00e+00	1305.00
IUUC-Vpa-130538	Vicugna pacos	84.69	0.00e+00	1562.00
IUUC-Xtr-132895	Xenopus tropicalis	71.01	0.00e+00	1096.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence