iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117486

Ensembl Protein ID

ENSTGUP00000007146.1

UniProt Accession

H0Z993; H0Z993_TAEGU

Genbank Protein ID

ENSTGUP00000007146

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01010616

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000006914.1	ENSTGUT00000007216.1	ENSTGUP00000007146.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.10e-17	63.3	7	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           de +++ +s++++r++++++ ++vld +l   l +e k    aaa   g++++ae+LL  +       gW refl
   Q: 7    DERFLYMISCFRPRLKQIIQAQPVLD-QLP-SLSAEDKDRVRAAALQRGAAAGAEELLRAVdrgPRGCGWIREFL 79
           68899*********************.887.899999999999999***************99888889***996 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MAEGTRDERF LYMISCFRPR LKQIIQAQPV LDQLPSLSAE DKDRVRAAAL QRGAAAGAEE 60
LLRAVDRGPR GCGWIREFLQ ALERGGCSLA ACYANPSLSQ LPSPAEEAEH DLCVHLVQLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAGG GCACCCGGGA CGAGCGGTTC CTGTACATGA TCTCCTGCTT CAGGCCGCGG 60
CTGAAGCAGA TCATCCAGGC GCAGCCCGTG CTGGACCAGC TCCCCTCGCT GAGCGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	59.81	0.00e+00	1112.00
IUUC-Apl-003900	Anas platyrhynchos	78.67	0.00e+00	1561.00
IUUC-Aca-005329	Anolis carolinensis	60.27	0.00e+00	1099.00
IUUC-Ame-011305	Astyanax mexicanus	48.02	0.00e+00	869.00
IUUC-Bta-012361	Bos taurus	58.57	0.00e+00	1070.00
IUUC-Bci-013755	Botrytis cinerea	45.45	1.00e-01	28.10
IUUC-Bdi-014006	Brachypodium distachyon	21.38	8.70e-02	32.30
IUUC-Cja-018760	Callithrix jacchus	59.50	0.00e+00	1064.00
IUUC-Cfa-020321	Canis familiaris	59.05	0.00e+00	1096.00
IUUC-Cpo-022450	Cavia porcellus	58.08	0.00e+00	1074.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	29.91	3.00e-10	60.80
IUUC-Csa-024194	Chlorocebus sabaeus	60.52	0.00e+00	1075.00
IUUC-Cho-024364	Choloepus hoffmanni	53.49	0.00e+00	727.00
IUUC-Dre-028305	Danio rerio	47.60	0.00e+00	788.00
IUUC-Dno-029831	Dasypus novemcinctus	59.46	0.00e+00	1110.00
IUUC-Dor-030410	Dipodomys ordii	65.49	0.00e+00	795.00
IUUC-Ete-032950	Echinops telfairi	61.33	2.00e-146	513.00
IUUC-Eca-034279	Equus caballus	59.67	0.00e+00	1104.00
IUUC-Eeu-034678	Erinaceus europaeus	57.93	0.00e+00	1082.00
IUUC-Fca-035618	Felis catus	64.62	0.00e+00	716.00
IUUC-Fal-037106	Ficedula albicollis	88.14	0.00e+00	1642.00
IUUC-Fso-038398	Fusarium solani	26.45	4.00e-29	123.00
IUUC-Gmo-038598	Gadus morhua	50.35	0.00e+00	697.00
IUUC-Gga-040467	Gallus gallus	80.23	0.00e+00	1583.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.54	0.00e+00	841.00
IUUC-Ggo-045461	Gorilla gorilla	60.14	0.00e+00	1069.00
IUUC-Hsa-045771	Homo sapiens	59.94	0.00e+00	1064.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	59.27	0.00e+00	1081.00
IUUC-Lch-049913	Latimeria chalumnae	64.22	0.00e+00	912.00
IUUC-Loc-052768	Lepisosteus oculatus	51.78	0.00e+00	994.00
IUUC-Laf-053933	Loxodonta africana	58.04	0.00e+00	1074.00
IUUC-Mcc-054695	Macaca mulatta	60.52	0.00e+00	1078.00
IUUC-Meu-056829	Macropus eugenii	60.62	0.00e+00	906.00
IUUC-Mga-059205	Meleagris gallopavo	79.57	0.00e+00	1582.00
IUUC-Mmr-060703	Microcebus murinus	59.24	0.00e+00	1070.00
IUUC-Mdo-063079	Monodelphis domestica	65.37	0.00e+00	988.00
IUUC-Mmu-064066	Mus musculus	58.62	0.00e+00	1118.00
IUUC-Mpu-066261	Mustela putorius furo	58.97	0.00e+00	1107.00
IUUC-Mlu-068196	Myotis lucifugus	57.73	0.00e+00	1055.00
IUUC-Nle-069479	Nomascus leucogenys	60.12	0.00e+00	1071.00
IUUC-Opr-070717	Ochotona princeps	53.05	0.00e+00	762.00
IUUC-Ont-071702	Oreochromis niloticus	47.11	0.00e+00	878.00
IUUC-Oan-073639	Ornithorhynchus anatinus	59.15	0.00e+00	1033.00
IUUC-Ocu-074521	Oryctolagus cuniculus	58.24	0.00e+00	1091.00
IUUC-Ola-086351	Oryzias latipes	53.07	0.00e+00	709.00
IUUC-Oga-088539	Otolemur garnettii	58.29	0.00e+00	1080.00
IUUC-Oar-090186	Ovis aries	59.35	0.00e+00	1067.00
IUUC-Ptr-090575	Pan troglodytes	59.53	0.00e+00	1062.00
IUUC-Pan-092371	Papio anubis	60.62	0.00e+00	1078.00
IUUC-Psi-093072	Pelodiscus sinensis	71.66	0.00e+00	1427.00
IUUC-Pma-094345	Petromyzon marinus	42.14	2.00e-92	332.00
IUUC-Pfo-096401	Poecilia formosa	46.15	0.00e+00	785.00
IUUC-Pab-097623	Pongo abelii	59.06	0.00e+00	1051.00
IUUC-Pca-100993	Procavia capensis	54.32	0.00e+00	873.00
IUUC-Pva-102227	Pteropus vampyrus	56.45	0.00e+00	1005.00
IUUC-Pgr-103529	Puccinia graminis	35.15	9.00e-16	79.30
IUUC-Rno-105198	Rattus norvegicus	58.67	0.00e+00	1101.00
IUUC-Sha-107622	Sarcophilus harrisii	59.46	0.00e+00	1151.00
IUUC-Sar-113625	Sorex araneus	68.28	1.00e-123	437.00
IUUC-Tru-118445	Takifugu rubripes	44.98	0.00e+00	820.00
IUUC-Tsy-119512	Tarsius syrichta	58.02	0.00e+00	1018.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.64	0.00e+00	828.00
IUUC-Tbe-127644	Tupaia belangeri	53.21	0.00e+00	950.00
IUUC-Ttr-128989	Tursiops truncatus	54.59	0.00e+00	1006.00
IUUC-Vpa-130587	Vicugna pacos	56.69	0.00e+00	898.00
IUUC-Xtr-132127	Xenopus tropicalis	51.70	0.00e+00	1000.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence