iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036972

Ensembl Protein ID

ENSFALP00000003093.1

UniProt Accession

U3JJY9; U3JJY9_FICAL

Genbank Protein ID

ENSFALP00000003093

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010641

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000002947.1	ENSFALT00000003106.1	ENSFALP00000003093.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.64	0.00e+00	1850.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGA EDTKHYEEGK KCVEELALYL KPLSSARGVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCCGGCTGC GGGGGAAGGC GGGCGCAGGA AGGGGCGGGT GGTGCGGAGA GGGAGGGAGG 60
GAGCGAGCTA GGTGGGCGGT GAGAGAAGCA GTCGACGCAC AAGATGGCCG CTGCCGGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	86.61	0.00e+00	1775.00
IUUC-Apl-003290	Anas platyrhynchos	93.98	0.00e+00	2006.00
IUUC-Aca-004905	Anolis carolinensis	84.06	0.00e+00	1791.00
IUUC-Ame-011475	Astyanax mexicanus	64.25	0.00e+00	1189.00
IUUC-Cja-019907	Callithrix jacchus	86.20	0.00e+00	1810.00
IUUC-Cfa-020679	Canis familiaris	85.83	0.00e+00	1749.00
IUUC-Cpo-022110	Cavia porcellus	84.63	0.00e+00	1795.00
IUUC-Csa-024166	Chlorocebus sabaeus	87.29	0.00e+00	1750.00
IUUC-Dor-030934	Dipodomys ordii	77.23	0.00e+00	1341.00
IUUC-Dme-031708	Drosophila melanogaster	64.93	2.00e-163	569.00
IUUC-Ete-032652	Echinops telfairi	85.37	0.00e+00	1247.00
IUUC-Eca-033236	Equus caballus	84.95	0.00e+00	1713.00
IUUC-Eeu-035091	Erinaceus europaeus	81.08	0.00e+00	857.00
IUUC-Fca-035773	Felis catus	86.03	0.00e+00	1747.00
IUUC-Gmo-039303	Gadus morhua	80.27	0.00e+00	900.00
IUUC-Ggo-044691	Gorilla gorilla	81.15	0.00e+00	1656.00
IUUC-Hsa-046163	Homo sapiens	86.81	0.00e+00	1813.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	77.25	0.00e+00	868.00
IUUC-Lch-050667	Latimeria chalumnae	71.99	0.00e+00	1494.00
IUUC-Loc-052404	Lepisosteus oculatus	69.83	0.00e+00	1341.00
IUUC-Laf-053618	Loxodonta africana	86.18	0.00e+00	1705.00
IUUC-Mcc-054692	Macaca mulatta	86.72	0.00e+00	1814.00
IUUC-Meu-056025	Macropus eugenii	75.97	0.00e+00	839.00
IUUC-Mmr-061188	Microcebus murinus	85.74	0.00e+00	1751.00
IUUC-Mdo-063035	Monodelphis domestica	84.70	0.00e+00	1782.00
IUUC-Mmu-064146	Mus musculus	84.34	0.00e+00	1750.00
IUUC-Mpu-066217	Mustela putorius furo	86.16	0.00e+00	1747.00
IUUC-Mlu-068023	Myotis lucifugus	84.50	0.00e+00	1745.00
IUUC-Nle-069506	Nomascus leucogenys	86.99	0.00e+00	1820.00
IUUC-Opr-070587	Ochotona princeps	73.01	0.00e+00	1417.00
IUUC-Ont-071278	Oreochromis niloticus	77.30	0.00e+00	888.00
IUUC-Oan-073500	Ornithorhynchus anatinus	86.67	0.00e+00	1843.00
IUUC-Ocu-074299	Oryctolagus cuniculus	85.45	0.00e+00	1665.00
IUUC-Ola-086665	Oryzias latipes	60.50	0.00e+00	1186.00
IUUC-Oga-088519	Otolemur garnettii	79.56	0.00e+00	1555.00
IUUC-Oar-089246	Ovis aries	85.55	0.00e+00	1659.00
IUUC-Ptr-091102	Pan troglodytes	86.90	0.00e+00	1815.00
IUUC-Pan-091952	Papio anubis	86.57	0.00e+00	1812.00
IUUC-Pfo-097227	Poecilia formosa	60.71	0.00e+00	1143.00
IUUC-Pab-097975	Pongo abelii	84.10	0.00e+00	1737.00
IUUC-Pca-101127	Procavia capensis	77.40	0.00e+00	1120.00
IUUC-Pva-102431	Pteropus vampyrus	77.95	0.00e+00	1535.00
IUUC-Sha-106690	Sarcophilus harrisii	84.37	0.00e+00	1789.00
IUUC-Ssc-116189	Sus scrofa	85.56	0.00e+00	1710.00
IUUC-Tgu-116527	Taeniopygia guttata	97.28	0.00e+00	2127.00
IUUC-Tru-118389	Takifugu rubripes	61.86	0.00e+00	1205.00
IUUC-Tsy-119193	Tarsius syrichta	83.11	0.00e+00	1684.00
IUUC-Tni-119790	Tetraodon nigroviridis	63.27	0.00e+00	1123.00
IUUC-Tbe-127445	Tupaia belangeri	89.05	0.00e+00	1220.00
IUUC-Ttr-128877	Tursiops truncatus	85.07	0.00e+00	1704.00
IUUC-Xtr-132274	Xenopus tropicalis	77.64	0.00e+00	1590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence