iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089246

Ensembl Protein ID

ENSOARP00000013939.1

UniProt Accession

W5PU08; W5PU08_SHEEP

Genbank Protein ID

ENSOARP00000013939

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01022148

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000013011.1	ENSOART00000014145.1	ENSOARP00000013939.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	96.49	0.00e+00	1847.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

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Nucleotide Sequence
(Fasta)

GTCTACTCTC CATCTCCAAA ATGAAGGGAT GAGACTAGTT GTTTTATTAT GGCTCTGATT 60
TTGTCAAAAT GCAAAGAAGG TGGACTGTGT TGATATAAAT GTGGTATAAA ATGCTATAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	96.40	0.00e+00	1926.00
IUUC-Apl-003290	Anas platyrhynchos	86.95	0.00e+00	1823.00
IUUC-Aca-004905	Anolis carolinensis	83.91	0.00e+00	1695.00
IUUC-Ame-011475	Astyanax mexicanus	77.96	0.00e+00	914.00
IUUC-Cja-019907	Callithrix jacchus	96.14	0.00e+00	1971.00
IUUC-Cfa-020679	Canis familiaris	96.23	0.00e+00	1923.00
IUUC-Cpo-022110	Cavia porcellus	90.90	0.00e+00	1919.00
IUUC-Csa-024166	Chlorocebus sabaeus	97.06	0.00e+00	1909.00
IUUC-Dno-029870	Dasypus novemcinctus	93.93	0.00e+00	939.00
IUUC-Dor-030934	Dipodomys ordii	86.78	0.00e+00	1460.00
IUUC-Dme-031708	Drosophila melanogaster	64.72	1.00e-162	566.00
IUUC-Ete-032652	Echinops telfairi	95.69	0.00e+00	1383.00
IUUC-Eca-033236	Equus caballus	95.70	0.00e+00	1903.00
IUUC-Eeu-035091	Erinaceus europaeus	82.56	0.00e+00	869.00
IUUC-Fca-035773	Felis catus	96.67	0.00e+00	1934.00
IUUC-Fal-036972	Ficedula albicollis	85.83	0.00e+00	1828.00
IUUC-Gmo-039303	Gadus morhua	81.51	0.00e+00	882.00
IUUC-Ggo-044691	Gorilla gorilla	90.19	0.00e+00	1811.00
IUUC-Hsa-046163	Homo sapiens	96.49	0.00e+00	1976.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	92.50	0.00e+00	1015.00
IUUC-Lch-050667	Latimeria chalumnae	73.36	0.00e+00	1510.00
IUUC-Loc-052404	Lepisosteus oculatus	68.59	0.00e+00	1312.00
IUUC-Laf-053618	Loxodonta africana	96.20	0.00e+00	1866.00
IUUC-Mcc-054692	Macaca mulatta	96.49	0.00e+00	1981.00
IUUC-Meu-056025	Macropus eugenii	84.05	0.00e+00	893.00
IUUC-Mmr-061188	Microcebus murinus	96.32	0.00e+00	1921.00
IUUC-Mdo-063035	Monodelphis domestica	91.59	0.00e+00	1850.00
IUUC-Mmu-064146	Mus musculus	91.75	0.00e+00	1867.00
IUUC-Mpu-066217	Mustela putorius furo	95.44	0.00e+00	1914.00
IUUC-Mlu-068023	Myotis lucifugus	94.82	0.00e+00	1916.00
IUUC-Nle-069506	Nomascus leucogenys	96.49	0.00e+00	1978.00
IUUC-Opr-070587	Ochotona princeps	81.90	0.00e+00	1559.00
IUUC-Ont-071278	Oreochromis niloticus	77.70	0.00e+00	886.00
IUUC-Oan-073500	Ornithorhynchus anatinus	91.28	0.00e+00	1899.00
IUUC-Ocu-074299	Oryctolagus cuniculus	95.11	0.00e+00	1807.00
IUUC-Ola-086665	Oryzias latipes	60.47	0.00e+00	1200.00
IUUC-Oga-088519	Otolemur garnettii	89.40	0.00e+00	1716.00
IUUC-Ptr-091102	Pan troglodytes	96.58	0.00e+00	1977.00
IUUC-Pan-091952	Papio anubis	96.67	0.00e+00	1984.00
IUUC-Pfo-097227	Poecilia formosa	78.06	0.00e+00	862.00
IUUC-Pab-097975	Pongo abelii	93.07	0.00e+00	1885.00
IUUC-Pca-101127	Procavia capensis	90.93	0.00e+00	1303.00
IUUC-Pva-102431	Pteropus vampyrus	87.37	0.00e+00	1723.00
IUUC-Sha-106690	Sarcophilus harrisii	90.62	0.00e+00	1844.00
IUUC-Sit-110791	Setaria italica	41.30	2.00e-05	43.10
IUUC-Sbi-114208	Sorghum bicolor	41.30	2.00e-05	42.70
IUUC-Ssc-116189	Sus scrofa	96.49	0.00e+00	1876.00
IUUC-Tgu-116527	Taeniopygia guttata	86.47	0.00e+00	1838.00
IUUC-Tru-118389	Takifugu rubripes	61.69	0.00e+00	1184.00
IUUC-Tsy-119193	Tarsius syrichta	92.63	0.00e+00	1854.00
IUUC-Tni-119790	Tetraodon nigroviridis	63.25	0.00e+00	1091.00
IUUC-Tbe-127445	Tupaia belangeri	90.47	0.00e+00	1505.00
IUUC-Ttr-128877	Tursiops truncatus	96.50	0.00e+00	1878.00
IUUC-Xtr-132274	Xenopus tropicalis	77.99	0.00e+00	1565.00
IUUC-Xma-134230	Xiphophorus maculatus	60.39	0.00e+00	1157.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence