iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000006969.6	ENSGALT00000011287.5	ENSGALP00000011273.5
ENSGALG00000006969.6	ENSGALT00000076766.1	ENSGALP00000044350.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-59	202.7	156	649

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +G+kN+gNtC++ +v+Q+L+++p++r+l+l+     +  e+++ +   +++ +++++lq lf+ ++ +++k v+p++ l+ l+++ ++ 
   Q: 156  VGMKNIGNTCWFSAVIQSLFQLPQFRRLVLSysfppNVLESCRTR-TGKRNIAFMQELQCLFALMLGTRRKFVDPSAALELLRDAFKS- 242
           6*******************************8887777777766.489999*******************************99998. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           ++ +qqD++Ef++ lld le++++                     + +++  k+++++++lF g++ ++ +    +n+ s+ e+f +++
   Q: 243  TEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVRSPGDKSENPMVQLFYGTFLTEGVH--EGNTFSKIETFGQYP 311
           789********************22..................34568999****************99887..6788899******** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e e+++      e+ +++++ +++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+++ ++
   Q: 312  LQVNGYR-----NLNECLEGAMVEGEMDE------ETATQSVKYVQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHTKLEFPQTIYMD 389
           *******.....9*****98888888876......5667777788899*************************************9999 PP
   S: 263  p..fcts.................................................................................. 267
           +  +c++                                                                                  
   Q: 390  RylYCSKeliqtkreemkklkekmlvlqqklerymkygsgparfplpdmlqyvlefittkpagavssacvsstedsqmmdrqsqgesli 478
           85567778888777777777777777777777777777777777777777777777777766666666666666666665555555555 PP
   S: 268  ...........peekqke....................................................................... 274
                      +                                                                             
   Q: 479  lgtpsqpdsmlD-----Gkdgkpedeavllansspqqqlnaplqpseppaemsdcpaphvvseeemnlvttclqrwrneieqdvrdlke 562
           555555555550.....055555555555555555556666777777777777777777777777777788888888888888888888 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                              ++ Y L+av+vH+G+++ GHY+a+++++ +k Wl+++D +Vte+++ee ++++      ++aY+l+Y 
   Q: 563  siarislsidemysdphlqQVPYHLHAVLVHEGQANAGHYWAFIYDQPRKsWLKYNDISVTESSWEELERDSFgglrnASAYCLMYI 649
           8888888888888888888***************************77667*******************8779************6 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

CAARLKIAPS SPRGALYDCQ VLNKMKEITG IQDADFLHAA LKAAKGNLME ALIVLTEERD 60
QEPVQNTAAA EPSSWEGSAV GKEPPQGGAA FDPEKKGDVH SAVAYGQLES PKAHAAERPQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGCGGGCG GGCGGCGCGG CCCCGCGGCG CGGGGGGTGG GGGTGGTCCG GCCCGGAGGG 60
ATGACGGCCG AGCTGCAGGC CGCGAGCGGC GGCCCGGCGG CCTCGAGGCG GTGAGCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	65.03	0.00e+00	1347.00
IUUC-Apl-004010	Anas platyrhynchos	80.57	0.00e+00	1739.00
IUUC-Bta-013377	Bos taurus	63.89	0.00e+00	1298.00
IUUC-Cel-018346	Caenorhabditis elegans	27.83	5.00e-30	126.00
IUUC-Cja-019977	Callithrix jacchus	64.92	0.00e+00	1333.00
IUUC-Cpo-021817	Cavia porcellus	63.89	0.00e+00	1315.00
IUUC-Csv-025911	Ciona savignyi	34.67	1.00e-142	500.00
IUUC-Cme-027167	Cyanidioschyzon merolae	26.15	2.00e-15	77.80
IUUC-Dno-029559	Dasypus novemcinctus	68.04	0.00e+00	1114.00
IUUC-Dor-030955	Dipodomys ordii	62.57	0.00e+00	1274.00
IUUC-Ete-032828	Echinops telfairi	59.35	0.00e+00	797.00
IUUC-Eca-034300	Equus caballus	64.76	0.00e+00	1311.00
IUUC-Eeu-034458	Erinaceus europaeus	61.65	0.00e+00	1139.00
IUUC-Fca-035753	Felis catus	64.56	0.00e+00	1333.00
IUUC-Fal-037062	Ficedula albicollis	75.36	0.00e+00	1063.00
IUUC-Gmo-039593	Gadus morhua	49.95	0.00e+00	974.00
IUUC-Ggo-045384	Gorilla gorilla	64.99	0.00e+00	1328.00
IUUC-Hsa-046277	Homo sapiens	65.05	0.00e+00	1333.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	65.52	0.00e+00	818.00
IUUC-Lch-049692	Latimeria chalumnae	58.95	0.00e+00	1213.00
IUUC-Laf-053808	Loxodonta africana	64.03	0.00e+00	1280.00
IUUC-Meu-056416	Macropus eugenii	55.32	0.00e+00	1057.00
IUUC-Mga-060011	Meleagris gallopavo	93.26	0.00e+00	1975.00
IUUC-Mmr-060720	Microcebus murinus	63.09	0.00e+00	1264.00
IUUC-Mmu-063870	Mus musculus	65.27	0.00e+00	1330.00
IUUC-Mpu-066454	Mustela putorius furo	63.04	0.00e+00	885.00
IUUC-Mlu-067487	Myotis lucifugus	61.16	0.00e+00	1231.00
IUUC-Nle-070044	Nomascus leucogenys	64.77	0.00e+00	1334.00
IUUC-Opr-070888	Ochotona princeps	74.46	4.00e-122	432.00
IUUC-Ocu-074523	Oryctolagus cuniculus	63.72	0.00e+00	1311.00
IUUC-Ola-086393	Oryzias latipes	51.39	0.00e+00	1021.00
IUUC-Oga-088618	Otolemur garnettii	64.10	0.00e+00	1310.00
IUUC-Ptr-091630	Pan troglodytes	65.71	0.00e+00	1046.00
IUUC-Psi-093422	Pelodiscus sinensis	68.70	0.00e+00	1035.00
IUUC-Pab-098337	Pongo abelii	65.23	0.00e+00	1335.00
IUUC-Pca-100901	Procavia capensis	65.77	0.00e+00	709.00
IUUC-Pva-102226	Pteropus vampyrus	59.84	0.00e+00	1136.00
IUUC-Sha-107489	Sarcophilus harrisii	65.58	0.00e+00	1348.00
IUUC-Tgu-116609	Taeniopygia guttata	76.43	0.00e+00	1550.00
IUUC-Tru-117807	Takifugu rubripes	50.93	0.00e+00	994.00
IUUC-Tsy-118971	Tarsius syrichta	61.52	0.00e+00	842.00
IUUC-Ttr-128887	Tursiops truncatus	60.98	0.00e+00	1241.00
IUUC-Vpa-130614	Vicugna pacos	64.00	0.00e+00	1007.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence