iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105913

UUCD1 version

UUC-RaN-00753

Ensembl Protein ID

ENSRNOP00000011948.3

UniProt Accession

A0A0H2UHH1; A0A0H2UHH1_RAT

Genbank Protein ID

ENSRNOP00000011948

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AC124896

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000008965.4	ENSRNOT00000011948.4	ENSRNOP00000011948.3

Annotation

mRNA Expression
ArrayExpress
DNA & RNA Element
miRNAMap
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.20e-13	51.1	153	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l ++ ++Lqh CRl+I++c+g+     i +LPLP +LkdYL+++++q
   Q: 153  TKPLYTSAPTLQHFCRLSINKCTGT-----IRGLPLPTRLKDYLEEYKFQ 197
           678999*******************.....7***************9886 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MTLRCLEPSG NGADRTRSQW GTAGSPEDQS PEAARLAKAL RELSQTGWYW GSMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGATGCA GCGGCTGGCG CACCGCTAGC GCACCGCAGC ACCCTCGGCT GGCGACCCAG 60
GAGCCCTGCG GCGCTTTAGG GCGTGGAACC AGGTTTTGCC GGATGCATCC TCCCCTAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	93.43	4.00e-103	366.00
IUUC-Apl-003484	Anas platyrhynchos	77.78	2.00e-70	257.00
IUUC-Aca-004253	Anolis carolinensis	70.12	4.00e-71	260.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	5.20e-02	32.00
IUUC-Ate-010256	Aspergillus terreus	45.45	1.90e+00	27.70
IUUC-Ame-011267	Astyanax mexicanus	61.08	1.00e-58	219.00
IUUC-Bta-013183	Bos taurus	91.92	1.00e-96	345.00
IUUC-Bra-017915	Brassica rapa	33.90	1.00e-01	30.80
IUUC-Cja-018862	Callithrix jacchus	92.93	1.00e-98	351.00
IUUC-Cfa-020226	Canis familiaris	92.39	1.00e-94	338.00
IUUC-Cpo-022414	Cavia porcellus	92.42	3.00e-100	357.00
IUUC-Csa-023758	Chlorocebus sabaeus	93.43	1.00e-101	361.00
IUUC-Cho-024471	Choloepus hoffmanni	82.69	8.00e-70	256.00
IUUC-Dre-028288	Danio rerio	55.72	4.00e-62	230.00
IUUC-Dno-029036	Dasypus novemcinctus	92.42	3.00e-103	367.00
IUUC-Dor-030447	Dipodomys ordii	96.03	3.00e-85	306.00
IUUC-Ete-033023	Echinops telfairi	90.40	5.00e-106	376.00
IUUC-Fca-036469	Felis catus	93.43	5.00e-98	349.00
IUUC-Fal-036642	Ficedula albicollis	72.22	7.00e-69	253.00
IUUC-Gmo-039331	Gadus morhua	53.97	2.00e-35	140.00
IUUC-Gga-040809	Gallus gallus	74.84	1.00e-70	258.00
IUUC-Gac-041398	Gasterosteus aculeatus	55.03	3.00e-58	217.00
IUUC-Ggo-045341	Gorilla gorilla	93.43	9.00e-99	352.00
IUUC-Hsa-046557	Homo sapiens	92.93	4.00e-109	386.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	76.44	4.00e-89	320.00
IUUC-Lch-050160	Latimeria chalumnae	62.00	4.00e-51	193.00
IUUC-Loc-051825	Lepisosteus oculatus	63.25	1.00e-60	225.00
IUUC-Laf-053560	Loxodonta africana	92.42	3.00e-96	343.00
IUUC-Mcc-055890	Macaca mulatta	92.42	1.00e-97	348.00
IUUC-Meu-056218	Macropus eugenii	78.79	1.00e-93	335.00
IUUC-Mga-059755	Meleagris gallopavo	67.76	2.00e-69	254.00
IUUC-Mmr-061387	Microcebus murinus	93.43	2.00e-100	357.00
IUUC-Mdo-062383	Monodelphis domestica	80.81	3.00e-94	337.00
IUUC-Mmu-063443	Mus musculus	96.97	9.00e-106	375.00
IUUC-Mpu-066459	Mustela putorius furo	92.93	2.00e-97	347.00
IUUC-Mlu-068040	Myotis lucifugus	93.43	4.00e-104	369.00
IUUC-Nle-069016	Nomascus leucogenys	88.38	6.00e-96	342.00
IUUC-Opr-071087	Ochotona princeps	86.87	2.00e-100	357.00
IUUC-Ont-072340	Oreochromis niloticus	59.30	2.00e-58	218.00
IUUC-Oan-073443	Ornithorhynchus anatinus	76.77	5.00e-88	316.00
IUUC-Ocu-074539	Oryctolagus cuniculus	93.94	3.00e-98	350.00
IUUC-Ogu-078951	Oryza glumaepatula	26.13	8.40e-02	31.60
IUUC-Oin-079476	Oryza indica	26.13	8.80e-02	31.60
IUUC-Oni-082613	Oryza nivara	26.13	8.80e-02	31.60
IUUC-Oru-085265	Oryza rufipogon	26.13	9.20e-02	31.60
IUUC-Ola-087004	Oryzias latipes	58.23	3.00e-54	203.00
IUUC-Oga-088438	Otolemur garnettii	92.93	4.00e-101	359.00
IUUC-Oar-089932	Ovis aries	91.92	2.00e-96	343.00
IUUC-Ptr-091037	Pan troglodytes	93.43	9.00e-99	352.00
IUUC-Pan-092767	Papio anubis	92.42	8.00e-98	348.00
IUUC-Psi-093099	Pelodiscus sinensis	74.84	1.00e-71	261.00
IUUC-Pma-094671	Petromyzon marinus	45.45	3.00e-37	148.00
IUUC-Pfo-097073	Poecilia formosa	53.11	3.00e-54	204.00
IUUC-Pab-098319	Pongo abelii	92.93	5.00e-104	369.00
IUUC-Pca-101117	Procavia capensis	90.40	1.00e-95	342.00
IUUC-Pva-102117	Pteropus vampyrus	91.92	5.00e-95	339.00
IUUC-Sha-106500	Sarcophilus harrisii	81.22	3.00e-93	333.00
IUUC-Ssc-115252	Sus scrofa	93.43	3.00e-101	360.00
IUUC-Tgu-117524	Taeniopygia guttata	74.84	1.00e-69	254.00
IUUC-Tsy-119335	Tarsius syrichta	91.39	3.00e-82	296.00
IUUC-Tni-120263	Tetraodon nigroviridis	57.23	1.00e-55	209.00
IUUC-Tca-121866	Theobroma cacao	38.10	5.50e-02	32.00
IUUC-Tbe-127915	Tupaia belangeri	91.41	2.00e-93	334.00
IUUC-Ttr-128372	Tursiops truncatus	92.93	1.00e-100	358.00
IUUC-Vpa-130422	Vicugna pacos	96.69	3.00e-85	306.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence