iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003568

Ensembl Protein ID

ENSAPLP00000015984.1

UniProt Accession

U3J906; U3J906_ANAPL

Genbank Protein ID

ENSAPLP00000015984

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01151525

Gene Name

RNF41

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000016094.1	ENSAPLT00000016794.1	ENSAPLP00000015984.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.40e-07	28.9	12	69
E3 activity/RING/RING	2.50e-06	27.6	18	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnl 59
           v e+++CpI   + ++Pv +p + + +  ++I +w++++++ cPv+r+ +t   l P  
   Q: 12   VDEDLICPICSGVLEEPVQAPhCEHAFCNACITQWFSQQQT-CPVDRSVVTVAHLRPVP 69
           56899******************************998887.******99999887764 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlp.CgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC   +++ p+  p C H+f+  C+ +w       s++++CP++r
   Q: 18   CPICSGVLEE-PVQAPhCEHAFCNACITQW------FSQQQTCPVDR 57
           ****999999.777777*************......********987 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MGYDVARFQG DVDEDLICPI CSGVLEEPVQ APHCEHAFCN ACITQWFSQQ QTCPVDRSVV 60
TVAHLRPVPR IMRNMLSKLQ ITCDNAVFGC TTAVVRLDNL MSHLNDCEHN PKRPVTCEQG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTAAGCTG TACGAGGAGG AAGGGGAAAA GATGGGCCAC TGGGAGCAGC TCCCTGCAAC 60
GAGTAACCCA GCCCCGGCCC TGCCTCTGTA CTGCTTAGGG AGGAATTCTG CCGCGGAAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008974--TRAF-like
IPR015036--USP8_interacting
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF08941--USP8_interact

SMART

SM00184--RING

Gene Ontology

GO:0016881--F:acid-amino acid ligase activity
GO:0031386--F:protein tag
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0030336--P:negative regulation of cell migration
GO:0008285--P:negative regulation of cell proliferation
GO:1901525--P:negative regulation of macromitophagy
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0010498--P:proteasomal protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:2000114--P:regulation of establishment of cell polarity
GO:0045619--P:regulation of lymphocyte differentiation
GO:0043408--P:regulation of MAPK cascade
GO:0045637--P:regulation of myeloid cell differentiation
GO:0051896--P:regulation of protein kinase B signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002398	Ailuropoda melanoleuca	95.91	0.00e+00	631.00
IUUC-Aca-005119	Anolis carolinensis	98.74	0.00e+00	644.00
IUUC-Ame-010708	Astyanax mexicanus	90.88	2.00e-176	610.00
IUUC-Bta-013428	Bos taurus	89.94	2.00e-170	590.00
IUUC-Cja-019844	Callithrix jacchus	95.92	0.00e+00	628.00
IUUC-Cfa-021124	Canis familiaris	96.23	0.00e+00	633.00
IUUC-Cpo-022325	Cavia porcellus	95.91	0.00e+00	632.00
IUUC-Csa-023113	Chlorocebus sabaeus	96.23	0.00e+00	633.00
IUUC-Cho-024991	Choloepus hoffmanni	96.92	1.00e-111	394.00
IUUC-Cne-026870	Cryptococcus neoformans	39.02	3.00e-19	90.10
IUUC-Dre-028730	Danio rerio	90.57	5.00e-176	609.00
IUUC-Dno-028908	Dasypus novemcinctus	95.83	4.00e-164	569.00
IUUC-Dor-030411	Dipodomys ordii	95.91	0.00e+00	632.00
IUUC-Dme-031868	Drosophila melanogaster	57.59	2.00e-108	384.00
IUUC-Ete-032896	Echinops telfairi	77.82	4.00e-118	416.00
IUUC-Eca-034135	Equus caballus	96.23	0.00e+00	633.00
IUUC-Eeu-034675	Erinaceus europaeus	95.91	0.00e+00	631.00
IUUC-Fca-035612	Felis catus	96.23	0.00e+00	633.00
IUUC-Fal-036922	Ficedula albicollis	98.77	9.00e-43	163.00
IUUC-Gmo-039648	Gadus morhua	87.42	1.00e-169	588.00
IUUC-Gga-040474	Gallus gallus	99.06	0.00e+00	646.00
IUUC-Gac-041951	Gasterosteus aculeatus	88.68	2.00e-172	597.00
IUUC-Ggo-045126	Gorilla gorilla	95.92	0.00e+00	628.00
IUUC-Hsa-046402	Homo sapiens	96.23	0.00e+00	633.00
IUUC-Itr-047895	Ictidomys tridecemlineatus	96.23	0.00e+00	633.00
IUUC-Lch-050266	Latimeria chalumnae	93.08	2.00e-179	620.00
IUUC-Loc-052547	Lepisosteus oculatus	91.82	3.00e-177	613.00
IUUC-Lma-053014	Leptosphaeria maculans	33.86	2.00e-11	63.20
IUUC-Laf-054332	Loxodonta africana	95.61	0.00e+00	628.00
IUUC-Mcc-055869	Macaca mulatta	96.23	0.00e+00	633.00
IUUC-Meu-056735	Macropus eugenii	96.18	2.00e-164	570.00
IUUC-Mga-060100	Meleagris gallopavo	99.06	0.00e+00	646.00
IUUC-Mmr-061382	Microcebus murinus	96.23	0.00e+00	633.00
IUUC-Mmu-064225	Mus musculus	95.91	0.00e+00	631.00
IUUC-Mpu-066709	Mustela putorius furo	96.23	0.00e+00	633.00
IUUC-Mlu-067168	Myotis lucifugus	95.28	0.00e+00	630.00
IUUC-Nle-070176	Nomascus leucogenys	96.23	0.00e+00	633.00
IUUC-Opr-070259	Ochotona princeps	95.91	0.00e+00	632.00
IUUC-Ont-071235	Oreochromis niloticus	89.94	9.00e-175	605.00
IUUC-Oan-072850	Ornithorhynchus anatinus	56.88	3.00e-89	320.00
IUUC-Ocu-074165	Oryctolagus cuniculus	95.91	0.00e+00	632.00
IUUC-Ola-086658	Oryzias latipes	88.36	6.00e-171	592.00
IUUC-Oga-088933	Otolemur garnettii	96.23	0.00e+00	633.00
IUUC-Oar-090089	Ovis aries	95.91	0.00e+00	632.00
IUUC-Ptr-091263	Pan troglodytes	96.23	0.00e+00	633.00
IUUC-Pan-092926	Papio anubis	96.23	0.00e+00	633.00
IUUC-Psi-093934	Pelodiscus sinensis	91.22	2.00e-168	583.00
IUUC-Pma-094578	Petromyzon marinus	67.50	3.00e-122	430.00
IUUC-Pno-094854	Phaeosphaeria nodorum	35.71	1.00e-12	67.80
IUUC-Pfo-097431	Poecilia formosa	89.94	2.00e-174	604.00
IUUC-Pab-097852	Pongo abelii	96.23	0.00e+00	633.00
IUUC-Pca-100496	Procavia capensis	88.09	3.00e-161	560.00
IUUC-Pva-103157	Pteropus vampyrus	96.52	5.00e-114	402.00
IUUC-Rno-105928	Rattus norvegicus	95.91	0.00e+00	631.00
IUUC-Sha-107556	Sarcophilus harrisii	96.24	0.00e+00	630.00
IUUC-Sar-113208	Sorex araneus	96.23	0.00e+00	633.00
IUUC-Ssc-116011	Sus scrofa	95.91	0.00e+00	632.00
IUUC-Tgu-116882	Taeniopygia guttata	74.37	2.00e-72	264.00
IUUC-Tru-117987	Takifugu rubripes	89.62	1.00e-173	601.00
IUUC-Tsy-118785	Tarsius syrichta	95.91	0.00e+00	626.00
IUUC-Tni-120165	Tetraodon nigroviridis	89.31	2.00e-173	600.00
IUUC-Tbe-127920	Tupaia belangeri	97.01	5.00e-116	409.00
IUUC-Ttr-129160	Tursiops truncatus	95.60	0.00e+00	630.00
IUUC-Vpa-130629	Vicugna pacos	96.23	0.00e+00	633.00
IUUC-Xtr-131895	Xenopus tropicalis	95.28	0.00e+00	629.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence