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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046193
Ensembl Protein ID ENSP00000399259.2
UniProt Accession Q86WN1; Q6UX75; Q86Y77; Q9NXX8; FCSD1_HUMAN
Genbank Protein ID AAO45099.1; AAQ88842.1; BAA92232.1; AAH47016.1
Protein Name F-BAR and double SH3 domains protein 1
Genbank Nucleotide ID AY217346; AY358478; AK000007; AC008781
Gene Name FCHSD1; UNQ737/PRO1431
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000197948.10 ENST00000435817.6 ENSP00000399259.2
ENSG00000197948.10 ENST00000522126.5 ENSP00000427796.1
ENSG00000197948.10 ENST00000522783.5 ENSP00000428677.1
ENSG00000197948.10 ENST00000518499.1 ENSP00000430448.1
ENSG00000197948.10 ENST00000519800.1 ENSP00000428776.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 5.80e-19 69.5 474 524
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFv 59
            v + y+a  +deLt+++G+ ++vi +e    +W+k+ ++ +g  G++Pe + 
   Q: 474  HVVFRYQAGREDELTITEGEWLEVI-EEGDADEWVKA-RNQHGEVGFVPERYL 524
           588**********************.7777789****.5***********996 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MQPPPRKVKP AQEVKLRFLE QLSILQTWQQ READLLEDIR SYSKQRAAIE REYGQALQKL 60
AGPFLKREGH RSGEMDSRGR TVFGAWRCLL DATVAGGQTR LQASDRYRDL AGGTGRSAKE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046193|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCTTCCTCC AGTTCCGGAG TCCAGTGGCT GACCGCCTTG CTGGAGCGGA GATGCAGCCG 60
CCGCCCCGAA AAGTGAGCTT GGCCCTGAAT GGGGACTCCT GGCGGGCTGG GGGAACGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046193|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR001452--SH3_domain
PROSITE

PS51741--F_BAR
PS50002--SH3
Pfam

PF00611--FCH
PF14604--SH3_9
SMART

SM00055--FCH
SM00326--SH3
Gene Ontology

GO:0031594--C:neuromuscular junction
GO:0055037--C:recycling endosome
GO:0007274--P:neuromuscular synaptic transmission
GO:0030833--P:regulation of actin filament polymerization
KEGG hsa:89848
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001547 Ailuropoda melanoleuca 91.19 0.00e+00 932.00
IUUC-Apl-003401 Anas platyrhynchos 44.14 4.00e-117 415.00
IUUC-Aca-004495 Anolis carolinensis 51.33 9.00e-172 597.00
IUUC-Bta-012414 Bos taurus 91.55 0.00e+00 928.00
IUUC-Cja-019001 Callithrix jacchus 94.50 0.00e+00 1092.00
IUUC-Cfa-020261 Canis familiaris 90.90 0.00e+00 1008.00
IUUC-Cpo-021303 Cavia porcellus 90.95 0.00e+00 1016.00
IUUC-Csa-024168 Chlorocebus sabaeus 96.96 0.00e+00 1063.00
IUUC-Dno-029012 Dasypus novemcinctus 84.02 0.00e+00 842.00
IUUC-Dor-030539 Dipodomys ordii 84.37 0.00e+00 909.00
IUUC-Ete-032615 Echinops telfairi 77.59 0.00e+00 801.00
IUUC-Eca-034431 Equus caballus 91.19 0.00e+00 852.00
IUUC-Eeu-035222 Erinaceus europaeus 76.37 5.00e-110 392.00
IUUC-Fca-036274 Felis catus 91.73 0.00e+00 967.00
IUUC-Gga-040200 Gallus gallus 46.23 2.00e-131 462.00
IUUC-Ggo-044698 Gorilla gorilla 98.94 0.00e+00 1126.00
IUUC-Itr-048848 Ictidomys tridecemlineatus 90.72 0.00e+00 1052.00
IUUC-Laf-053614 Loxodonta africana 89.34 0.00e+00 967.00
IUUC-Mcc-055801 Macaca mulatta 96.11 0.00e+00 1074.00
IUUC-Meu-055969 Macropus eugenii 74.71 0.00e+00 760.00
IUUC-Mga-059428 Meleagris gallopavo 47.65 3.00e-143 502.00
IUUC-Mvi-060384 Microbotryum violaceum 33.68 1.00e-06 48.50
IUUC-Mmr-060884 Microcebus murinus 94.22 0.00e+00 1004.00
IUUC-Mdo-062232 Monodelphis domestica 79.55 0.00e+00 858.00
IUUC-Mmu-063768 Mus musculus 90.88 0.00e+00 1011.00
IUUC-Mpu-066271 Mustela putorius furo 91.20 0.00e+00 974.00
IUUC-Mlu-067436 Myotis lucifugus 75.61 0.00e+00 785.00
IUUC-Nle-069391 Nomascus leucogenys 97.12 0.00e+00 1071.00
IUUC-Opr-070480 Ochotona princeps 79.19 0.00e+00 881.00
IUUC-Ont-072392 Oreochromis niloticus 43.85 3.00e-130 459.00
IUUC-Oan-073048 Ornithorhynchus anatinus 52.61 7.00e-116 410.00
IUUC-Ocu-074813 Oryctolagus cuniculus 91.55 0.00e+00 1010.00
IUUC-Ola-087476 Oryzias latipes 45.72 4.00e-124 438.00
IUUC-Oga-088857 Otolemur garnettii 92.47 0.00e+00 1012.00
IUUC-Oar-090308 Ovis aries 90.70 0.00e+00 916.00
IUUC-Ptr-091590 Pan troglodytes 99.26 0.00e+00 866.00
IUUC-Pan-091724 Papio anubis 96.38 0.00e+00 1096.00
IUUC-Pfo-096841 Poecilia formosa 43.30 5.00e-113 402.00
IUUC-Pab-098670 Pongo abelii 94.85 0.00e+00 1018.00
IUUC-Pca-100339 Procavia capensis 89.01 0.00e+00 973.00
IUUC-Pva-102174 Pteropus vampyrus 90.24 0.00e+00 1002.00
IUUC-Rno-105310 Rattus norvegicus 90.58 0.00e+00 1001.00
IUUC-Sha-106670 Sarcophilus harrisii 78.13 0.00e+00 783.00
IUUC-Ssc-115785 Sus scrofa 90.09 0.00e+00 854.00
IUUC-Tbe-128036 Tupaia belangeri 90.08 0.00e+00 739.00
IUUC-Ttr-129270 Tursiops truncatus 91.29 0.00e+00 954.00
IUUC-Xtr-132140 Xenopus tropicalis 48.82 6.00e-152 531.00
Created Date 25-Jun-2017

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