iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073367

Ensembl Protein ID

ENSOANP00000001123.3

UniProt Accession

F6ZDW2; F6ZDW2_ORNAN

Genbank Protein ID

ENSOANP00000001123

Protein Name

Histone acetyltransferase

Genbank Nucleotide ID

AAPN01350591

Gene Name

KAT6A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000718.3	ENSOANT00000001124.3	ENSOANP00000001123.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.30e-09	37.5	264	313

Active Site

Position(s)	Description	Evidence
680	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 264  KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 313
           68999******99*********************.9*****97.******85 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK LDGKQNVDWN KLIKRAIEGL AESGGSTLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGATTTTTT GGGATAAGAA AGTGACGTTG TTTTCATTTT CTTTCAGGTT TGACCTACAC 60
ATTTCTCTGA CCCGAACCTG GAGACCTGGG AGGAGCAGTG AGATATTCTG AGTTCCTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR015943--WD40/YVTN_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00526--H15
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0000786--C:nucleosome
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated

KEGG

oaa:100076656

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	86.73	0.00e+00	2939.00
IUUC-Aca-004549	Anolis carolinensis	76.07	0.00e+00	1704.00
IUUC-Ame-010711	Astyanax mexicanus	70.82	1.00e-178	621.00
IUUC-Bta-013426	Bos taurus	82.43	0.00e+00	2140.00
IUUC-Cja-019124	Callithrix jacchus	87.01	0.00e+00	1911.00
IUUC-Cfa-021165	Canis familiaris	88.18	0.00e+00	2361.00
IUUC-Cpo-022332	Cavia porcellus	79.98	0.00e+00	1524.00
IUUC-Cne-026801	Cryptococcus neoformans	63.59	1.00e-73	271.00
IUUC-Dre-028624	Danio rerio	79.38	0.00e+00	671.00
IUUC-Dno-029878	Dasypus novemcinctus	81.67	0.00e+00	1825.00
IUUC-Ete-032342	Echinops telfairi	89.75	0.00e+00	1764.00
IUUC-Eca-033925	Equus caballus	87.34	0.00e+00	2313.00
IUUC-Fca-035985	Felis catus	88.00	0.00e+00	2367.00
IUUC-Gmo-039182	Gadus morhua	74.69	0.00e+00	1194.00
IUUC-Gga-041028	Gallus gallus	84.28	0.00e+00	1888.00
IUUC-Gac-042131	Gasterosteus aculeatus	73.18	0.00e+00	1183.00
IUUC-Gma-044341	Glycine max	42.37	4.00e-10	60.10
IUUC-Ggo-044664	Gorilla gorilla	86.58	0.00e+00	1904.00
IUUC-Hsa-046832	Homo sapiens	86.58	0.00e+00	1905.00
IUUC-Loc-052537	Lepisosteus oculatus	76.65	0.00e+00	1246.00
IUUC-Laf-053686	Loxodonta africana	87.78	0.00e+00	2329.00
IUUC-Mcc-055429	Macaca mulatta	86.67	0.00e+00	1914.00
IUUC-Mvi-060531	Microbotryum violaceum	54.91	3.00e-72	266.00
IUUC-Mmr-061249	Microcebus murinus	84.84	0.00e+00	2253.00
IUUC-Mdo-062826	Monodelphis domestica	78.49	0.00e+00	694.00
IUUC-Mmu-063474	Mus musculus	82.32	0.00e+00	2254.00
IUUC-Mpu-066585	Mustela putorius furo	87.30	0.00e+00	2360.00
IUUC-Mlu-066965	Myotis lucifugus	86.51	0.00e+00	2258.00
IUUC-Nle-069270	Nomascus leucogenys	86.66	0.00e+00	1907.00
IUUC-Opr-070963	Ochotona princeps	75.63	0.00e+00	1605.00
IUUC-Ont-071466	Oreochromis niloticus	71.19	0.00e+00	629.00
IUUC-Ocu-074100	Oryctolagus cuniculus	80.08	0.00e+00	1729.00
IUUC-Ola-087293	Oryzias latipes	73.56	0.00e+00	1192.00
IUUC-Oga-089052	Otolemur garnettii	90.99	0.00e+00	818.00
IUUC-Oar-089692	Ovis aries	83.32	0.00e+00	1813.00
IUUC-Ptr-091107	Pan troglodytes	86.42	0.00e+00	1884.00
IUUC-Pan-092524	Papio anubis	86.52	0.00e+00	1912.00
IUUC-Pfo-096641	Poecilia formosa	70.21	0.00e+00	1176.00
IUUC-Pab-098311	Pongo abelii	87.08	0.00e+00	1916.00
IUUC-Pca-100810	Procavia capensis	82.59	0.00e+00	1680.00
IUUC-Pgr-103522	Puccinia graminis	50.40	8.00e-69	254.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	36.67	4.00e-46	179.00
IUUC-Rno-104990	Rattus norvegicus	82.37	0.00e+00	1849.00
IUUC-Sha-106816	Sarcophilus harrisii	89.61	0.00e+00	2405.00
IUUC-Sre-115066	Sporisorium reilianum	55.56	9.00e-78	285.00
IUUC-Tgu-116639	Taeniopygia guttata	84.68	0.00e+00	1913.00
IUUC-Tru-118571	Takifugu rubripes	71.82	0.00e+00	1216.00
IUUC-Tni-119936	Tetraodon nigroviridis	75.47	0.00e+00	1235.00
IUUC-Tbe-127928	Tupaia belangeri	96.95	0.00e+00	1583.00
IUUC-Uma-129445	Ustilago maydis	56.84	1.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence