iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048297

Ensembl Protein ID

ENSSTOP00000000336.2

UniProt Accession

I3LWH9; I3LWH9_ICTTR

Genbank Protein ID

ENSSTOP00000000336

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01062232

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000000372.2	ENSSTOT00000000373.2	ENSSTOP00000000336.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-21	76.1	311	357

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 311  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 357
           8********988.6*******************.*******7.******5 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MEPATALPQG PRPALPLGSP GPLGEFLPPP ECPVFEPSWE EFADPFAFIH KIRPIAEQTG 60
ICKVRPPPDW QPPFACDVDK LHFTPRIQRL NELEAQTRVK LNFLDQIAKY WELQGSTLKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTCGTCGGA GGAAGGCTGA AAAAGCCCAA GGTGCTGCCG TTGCTAGTAC AAGTCGGACT 60
TGCTATCGCC CGAGCCGCGT CTGTACAGGT CTCGGACAGA GCGGAGCTCG CAGCCGCGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.35	6.00e-102	365.00
IUUC-Aml-001963	Ailuropoda melanoleuca	96.61	0.00e+00	2784.00
IUUC-Atr-002595	Amborella trichopoda	33.81	4.00e-121	430.00
IUUC-Apl-003770	Anas platyrhynchos	86.40	0.00e+00	2179.00
IUUC-Aca-004867	Anolis carolinensis	82.21	0.00e+00	2511.00
IUUC-Ath-007218	Arabidopsis thaliana	35.56	3.00e-09	58.50
IUUC-Acl-008162	Aspergillus clavatus	31.70	2.00e-115	410.00
IUUC-Ani-009139	Aspergillus nidulans	30.94	1.00e-109	392.00
IUUC-Ame-010620	Astyanax mexicanus	62.52	0.00e+00	1925.00
IUUC-Bta-012733	Bos taurus	91.64	0.00e+00	2661.00
IUUC-Bdi-014050	Brachypodium distachyon	29.66	4.00e-123	436.00
IUUC-Bol-015336	Brassica oleracea	36.45	2.00e-14	75.90
IUUC-Cja-019050	Callithrix jacchus	96.76	0.00e+00	2898.00
IUUC-Cfa-021015	Canis familiaris	96.68	0.00e+00	2776.00
IUUC-Cpo-022340	Cavia porcellus	96.75	0.00e+00	2753.00
IUUC-Csa-023441	Chlorocebus sabaeus	97.62	0.00e+00	2877.00
IUUC-Cho-024823	Choloepus hoffmanni	98.08	0.00e+00	1706.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	30.00	7.00e-108	385.00
IUUC-Cne-026851	Cryptococcus neoformans	28.85	1.00e-112	401.00
IUUC-Dre-027707	Danio rerio	61.46	0.00e+00	1847.00
IUUC-Dno-028978	Dasypus novemcinctus	96.49	0.00e+00	2841.00
IUUC-Dor-030854	Dipodomys ordii	86.92	0.00e+00	1926.00
IUUC-Ete-032760	Echinops telfairi	91.20	0.00e+00	1852.00
IUUC-Eca-034370	Equus caballus	97.22	0.00e+00	2720.00
IUUC-Eeu-035012	Erinaceus europaeus	76.96	0.00e+00	1887.00
IUUC-Fca-035494	Felis catus	97.29	0.00e+00	2782.00
IUUC-Fal-037631	Ficedula albicollis	83.31	0.00e+00	2422.00
IUUC-Gmo-039522	Gadus morhua	59.13	0.00e+00	1743.00
IUUC-Ggr-039929	Gaeumannomyces graminis	28.29	5.00e-103	369.00
IUUC-Gga-040802	Gallus gallus	83.86	0.00e+00	2461.00
IUUC-Gac-041563	Gasterosteus aculeatus	62.62	0.00e+00	1865.00
IUUC-Gma-042675	Glycine max	32.70	1.00e-101	365.00
IUUC-Ggo-044856	Gorilla gorilla	79.38	0.00e+00	2178.00
IUUC-Hsa-045888	Homo sapiens	95.42	0.00e+00	2890.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	7.00e-16	79.30
IUUC-Kpa-049245	Komagataella pastoris	21.50	9.00e-32	132.00
IUUC-Lch-050483	Latimeria chalumnae	66.65	0.00e+00	2051.00
IUUC-Lpe-051537	Leersia perrieri	31.69	2.00e-91	330.00
IUUC-Loc-052550	Lepisosteus oculatus	71.31	0.00e+00	2125.00
IUUC-Laf-053761	Loxodonta africana	94.78	0.00e+00	2717.00
IUUC-Mcc-055505	Macaca mulatta	95.35	0.00e+00	2884.00
IUUC-Meu-056467	Macropus eugenii	88.49	0.00e+00	1053.00
IUUC-Mpo-057317	Magnaporthe poae	28.89	3.00e-106	380.00
IUUC-Mga-059358	Meleagris gallopavo	82.88	0.00e+00	2433.00
IUUC-Mmr-060863	Microcebus murinus	97.56	0.00e+00	2870.00
IUUC-Mdo-061957	Monodelphis domestica	89.61	0.00e+00	2702.00
IUUC-Mmu-063944	Mus musculus	94.45	0.00e+00	2774.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	56.20
IUUC-Mpu-066719	Mustela putorius furo	94.86	0.00e+00	2834.00
IUUC-Mlu-067366	Myotis lucifugus	86.00	0.00e+00	2558.00
IUUC-Nle-069256	Nomascus leucogenys	94.38	0.00e+00	2843.00
IUUC-Opr-071002	Ochotona princeps	51.55	0.00e+00	1264.00
IUUC-Ont-071756	Oreochromis niloticus	62.46	0.00e+00	1906.00
IUUC-Oan-073568	Ornithorhynchus anatinus	90.04	0.00e+00	2703.00
IUUC-Ocu-073961	Oryctolagus cuniculus	93.32	0.00e+00	2770.00
IUUC-Oba-075388	Oryza barthii	30.91	6.00e-81	296.00
IUUC-Obr-076296	Oryza brachyantha	39.77	2.00e-88	322.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	9.00e-17	82.40
IUUC-Ogu-079040	Oryza glumaepatula	26.73	5.00e-75	276.00
IUUC-Olo-080668	Oryza longistaminata	38.83	3.00e-16	81.60
IUUC-Ome-081764	Oryza meridionalis	28.64	9.00e-95	342.00
IUUC-Oni-083012	Oryza nivara	30.22	2.00e-74	275.00
IUUC-Oru-084630	Oryza rufipogon	30.55	4.00e-81	296.00
IUUC-Osa-085487	Oryza sativa	38.83	9.00e-17	82.40
IUUC-Ola-086448	Oryzias latipes	62.24	0.00e+00	1862.00
IUUC-Oga-088501	Otolemur garnettii	92.75	0.00e+00	2390.00
IUUC-Oar-090162	Ovis aries	91.17	0.00e+00	2641.00
IUUC-Ptr-090816	Pan troglodytes	95.35	0.00e+00	2890.00
IUUC-Pan-092764	Papio anubis	97.62	0.00e+00	2876.00
IUUC-Psi-093918	Pelodiscus sinensis	83.12	0.00e+00	2235.00
IUUC-Ppa-095839	Physcomitrella patens	38.78	4.00e-16	81.30
IUUC-Pfo-096672	Poecilia formosa	62.56	0.00e+00	1835.00
IUUC-Pab-097854	Pongo abelii	94.28	0.00e+00	2206.00
IUUC-Pca-100241	Procavia capensis	91.27	0.00e+00	1797.00
IUUC-Pva-103035	Pteropus vampyrus	85.65	0.00e+00	2215.00
IUUC-Rno-105574	Rattus norvegicus	93.13	0.00e+00	2715.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.59	4.00e-74	272.00
IUUC-Sit-110534	Setaria italica	32.78	2.00e-100	361.00
IUUC-Sly-111298	Solanum lycopersicum	42.66	6.00e-103	369.00
IUUC-Sar-113477	Sorex araneus	91.28	0.00e+00	2433.00
IUUC-Ssc-116132	Sus scrofa	94.97	0.00e+00	2432.00
IUUC-Tgu-117452	Taeniopygia guttata	83.83	0.00e+00	2424.00
IUUC-Tru-117561	Takifugu rubripes	63.65	0.00e+00	1742.00
IUUC-Tsy-119271	Tarsius syrichta	95.27	0.00e+00	2186.00
IUUC-Tni-119650	Tetraodon nigroviridis	61.67	0.00e+00	1837.00
IUUC-Tae-125894	Triticum aestivum	32.35	3.00e-103	370.00
IUUC-Tur-126632	Triticum urartu	32.47	3.00e-101	363.00
IUUC-Tbe-127890	Tupaia belangeri	91.90	0.00e+00	1569.00
IUUC-Ttr-128546	Tursiops truncatus	90.61	0.00e+00	2015.00
IUUC-Vda-129733	Verticillium dahliae	29.54	7.00e-98	352.00
IUUC-Vpa-130432	Vicugna pacos	90.13	0.00e+00	1580.00
IUUC-Xtr-132008	Xenopus tropicalis	71.28	0.00e+00	2141.00
IUUC-Xma-133571	Xiphophorus maculatus	62.60	0.00e+00	1872.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence