iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132979

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAMC01124965

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000012585.3	ENSXETT00000027543.3	ENSXETP00000027543.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.10e-81	273.1	377	725

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtre.....flallskelqnpdlglf.lysendketlqpnpdsglknpehlklFeflGrllgkalqd 84
           ++dl krl+++f+gEegld+gGv+r      f +l+++    p +g +  y  ++ +t ++ ++ g++  ehl++F+f+Gr++g+a+++
   Q: 377  PKDLWKRLMIKFRGEEGLDYGGVARMskailFCKLICHGYLYPRYGYWyGYRRSNFNTKETPSELGMCYMEHLSYFHFVGRIMGMAVFH 465
           678999*****************9964555588999************6444445555555555566677******************* PP
   S: 85   grlldlplsksfyklllgkklsledleevdpelykslkeikenaes.....dieelgldltfsvseeilgetkeeeLkpgGenipVtne 168
           g+++d  ++ +fyk+llgk+++l+d+e+vdp+l++sl +i+   +       i+  +l  ++s s + +++ ++  L+   +++p  ++
   Q: 466  GHYIDGGFTLPFYKQLLGKPITLDDMESVDPDLHNSLVWILFPLDLpvppqLITF-CLLSAVSYSLSAVSYSHSASLI---ASVPYLIA 550
           *****************************************66533332212222.2333333444445555555555...45666677 PP
   S: 169  NkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefs 257
              + + l+v++r+ +gi+ q+ a+++Gfnevip++ll++F+e+elel+icG  +idv+d+k++t+ k+ +t+ds+ ++wFw+++e+f+
   Q: 551  SVPDLIALYVNWRFLRGIEAQFLALQKGFNEVIPQHLLKAFDEKELELIICGLGKIDVNDWKSNTRLKH-CTADSNIVKWFWKAVESFD 638
           899****************************************************************99.******************* PP
   S: 258  seerkafLqFvTgssrlPlgGfaelk.....prlfvirk........dasd.drlPssn.TCfnyLkLPeYsskeilkekLlyAieetk 331
           +e r+++LqFvTgssr+Pl+Gf++l+     +                + + +  P ++   fn++++P+Y+++e+l+ekLl+Aieet 
   Q: 639  EERRARLLQFVTGSSRVPLQGFKALQecrglR------GrvpwsaggRGGEfHGVPGAQgASFNRIDIPPYETYEKLYEKLLTAIEETC 721
           **************************665541......22344567744555999*998457*************************** PP
   S: 332  gFel 335
           gF +
   Q: 722  GFAV 725
           **76 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

ISFTVLCAKN LVKKDFFRLP DPFAKVVVDG SGQCHSTDTV KNTLDPKWNQ HYDLYIGKSD 60
SITISVWNHK KIHKKQGAGF LGCVRLLSNA INRLKDTGYQ RLDLCKLGPN DNDTVRGQIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTCATTCA CAGTGCTGTG CGCTAAAAAT CTGGTGAAAA AGGATTTCTT CAGTGAGTAT 60
TACAGTAACT CATAGGTCAA TTGCCCCTGC CAATAGTGCC TGTGTGCCTG GCCGGTACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001305	Ailuropoda melanoleuca	78.81	0.00e+00	1142.00
IUUC-Apl-003513	Anas platyrhynchos	79.26	0.00e+00	1162.00
IUUC-Aca-005358	Anolis carolinensis	78.63	0.00e+00	1154.00
IUUC-Ame-011320	Astyanax mexicanus	72.47	0.00e+00	1085.00
IUUC-Bta-013399	Bos taurus	78.83	0.00e+00	1137.00
IUUC-Cja-019355	Callithrix jacchus	78.75	0.00e+00	1135.00
IUUC-Cpo-022200	Cavia porcellus	78.88	0.00e+00	1142.00
IUUC-Cin-025126	Ciona intestinalis	54.71	0.00e+00	743.00
IUUC-Csv-026339	Ciona savignyi	54.20	0.00e+00	764.00
IUUC-Dre-027650	Danio rerio	74.58	0.00e+00	1109.00
IUUC-Dno-029534	Dasypus novemcinctus	78.68	0.00e+00	1138.00
IUUC-Ete-032715	Echinops telfairi	73.87	0.00e+00	1047.00
IUUC-Eca-033580	Equus caballus	78.75	0.00e+00	1137.00
IUUC-Eeu-034945	Erinaceus europaeus	78.96	0.00e+00	1050.00
IUUC-Fal-037275	Ficedula albicollis	78.76	0.00e+00	1150.00
IUUC-Gmo-039234	Gadus morhua	79.95	0.00e+00	680.00
IUUC-Gga-041060	Gallus gallus	75.43	0.00e+00	1081.00
IUUC-Gac-041295	Gasterosteus aculeatus	75.95	0.00e+00	1115.00
IUUC-Hsa-046726	Homo sapiens	78.68	0.00e+00	1137.00
IUUC-Lch-050026	Latimeria chalumnae	77.84	0.00e+00	1122.00
IUUC-Loc-051760	Lepisosteus oculatus	73.16	0.00e+00	1093.00
IUUC-Laf-053753	Loxodonta africana	78.72	0.00e+00	1137.00
IUUC-Mcc-054815	Macaca mulatta	78.54	0.00e+00	1134.00
IUUC-Mmr-060806	Microcebus murinus	78.83	0.00e+00	1136.00
IUUC-Mdo-062805	Monodelphis domestica	77.75	0.00e+00	1122.00
IUUC-Mmu-064034	Mus musculus	78.54	0.00e+00	1137.00
IUUC-Mpu-066762	Mustela putorius furo	78.68	0.00e+00	1139.00
IUUC-Mlu-066981	Myotis lucifugus	78.72	0.00e+00	1135.00
IUUC-Nle-069804	Nomascus leucogenys	78.68	0.00e+00	1137.00
IUUC-Opr-070591	Ochotona princeps	73.73	0.00e+00	1043.00
IUUC-Ont-071239	Oreochromis niloticus	75.82	0.00e+00	1112.00
IUUC-Oan-072699	Ornithorhynchus anatinus	75.77	0.00e+00	1127.00
IUUC-Ocu-074913	Oryctolagus cuniculus	78.54	0.00e+00	1138.00
IUUC-Oga-089116	Otolemur garnettii	75.80	0.00e+00	1079.00
IUUC-Oar-089366	Ovis aries	78.75	0.00e+00	1140.00
IUUC-Ptr-091382	Pan troglodytes	78.68	0.00e+00	1137.00
IUUC-Psi-093298	Pelodiscus sinensis	79.52	0.00e+00	1131.00
IUUC-Pma-094354	Petromyzon marinus	63.71	0.00e+00	908.00
IUUC-Pab-098682	Pongo abelii	78.68	0.00e+00	1138.00
IUUC-Pva-102754	Pteropus vampyrus	78.27	0.00e+00	1117.00
IUUC-Sha-107144	Sarcophilus harrisii	76.60	0.00e+00	1014.00
IUUC-Sar-113122	Sorex araneus	69.07	0.00e+00	954.00
IUUC-Tgu-117112	Taeniopygia guttata	78.20	0.00e+00	1144.00
IUUC-Tbe-127371	Tupaia belangeri	71.00	0.00e+00	908.00
IUUC-Ttr-129305	Tursiops truncatus	78.79	0.00e+00	1047.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence