iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048762

Ensembl Protein ID

ENSSTOP00000004468.2

UniProt Accession

I3M585; I3M585_ICTTR

Genbank Protein ID

ENSSTOP00000004468

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01000298

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004953.2	ENSSTOT00000004981.2	ENSSTOP00000004468.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	4.20e-45	152.2	8	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           d ++r+l+s+++ r++ +++v++vld yl+ fl +e+ke+i ++++t+gnm a+elLL+tL   v+  gW+ref+
   Q: 8    DKNFRYLISCFRVRLKSYIQVEPVLD-YLT-FLTNEVKEQIRRTVATSGNMRAVELLLNTLekeVWSPGWTREFV 80
           789***********************.***.*******************************************6 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MSNGFSADKN FRYLISCFRV RLKSYIQVEP VLDYLTFLTN EVKEQIRRTV ATSGNMRAVE 60
LLLNTLEKEV WSPGWTREFV VALQRTGNTL AARYVNPDLT DLPSPSFEKA HDECLQLLNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGAATG GGTTCTCTGC AGACAAGAAC TTTCGCTACC TCATCTCTTG CTTCAGGGTC 60
AGATTGAAAA GTTACATCCA GGTAGAGCCC GTCCTGGACT ACTTGACCTT TCTGACTAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR001315--CARD
IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS50209--CARD
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	80.25	0.00e+00	1567.00
IUUC-Apl-003900	Anas platyrhynchos	60.86	0.00e+00	1197.00
IUUC-Aca-005329	Anolis carolinensis	58.49	0.00e+00	1003.00
IUUC-Ame-011305	Astyanax mexicanus	46.65	0.00e+00	855.00
IUUC-Bta-012361	Bos taurus	80.49	0.00e+00	1519.00
IUUC-Cja-018760	Callithrix jacchus	82.73	0.00e+00	1547.00
IUUC-Cfa-020321	Canis familiaris	79.67	0.00e+00	1502.00
IUUC-Cpo-022450	Cavia porcellus	79.45	0.00e+00	1569.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	33.33	2.00e-12	68.20
IUUC-Csa-024194	Chlorocebus sabaeus	86.24	0.00e+00	1583.00
IUUC-Cho-024364	Choloepus hoffmanni	73.01	0.00e+00	1001.00
IUUC-Dre-028305	Danio rerio	46.71	0.00e+00	782.00
IUUC-Dno-029831	Dasypus novemcinctus	81.85	0.00e+00	1579.00
IUUC-Dor-030410	Dipodomys ordii	76.68	0.00e+00	1234.00
IUUC-Ete-032950	Echinops telfairi	75.46	0.00e+00	646.00
IUUC-Eca-034279	Equus caballus	82.85	0.00e+00	1566.00
IUUC-Eeu-034678	Erinaceus europaeus	78.56	0.00e+00	1545.00
IUUC-Fca-035618	Felis catus	83.66	0.00e+00	943.00
IUUC-Fal-037106	Ficedula albicollis	58.75	0.00e+00	1092.00
IUUC-Gmo-038598	Gadus morhua	49.93	0.00e+00	684.00
IUUC-Gga-040467	Gallus gallus	60.60	0.00e+00	1171.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.83	0.00e+00	842.00
IUUC-Ggo-045461	Gorilla gorilla	86.34	0.00e+00	1579.00
IUUC-Hsa-045771	Homo sapiens	85.95	0.00e+00	1576.00
IUUC-Lch-049913	Latimeria chalumnae	65.95	0.00e+00	924.00
IUUC-Loc-052768	Lepisosteus oculatus	53.63	0.00e+00	979.00
IUUC-Laf-053933	Loxodonta africana	80.93	0.00e+00	1528.00
IUUC-Mcc-054695	Macaca mulatta	86.44	0.00e+00	1590.00
IUUC-Meu-056829	Macropus eugenii	72.08	0.00e+00	1105.00
IUUC-Mga-059205	Meleagris gallopavo	60.51	0.00e+00	1168.00
IUUC-Mvi-060497	Microbotryum violaceum	32.60	6.00e-18	87.00
IUUC-Mmr-060703	Microcebus murinus	83.33	0.00e+00	1530.00
IUUC-Mdo-063079	Monodelphis domestica	71.40	0.00e+00	1442.00
IUUC-Mmu-064066	Mus musculus	78.75	0.00e+00	1579.00
IUUC-Mpu-066261	Mustela putorius furo	80.70	0.00e+00	1536.00
IUUC-Mlu-068196	Myotis lucifugus	79.43	0.00e+00	1502.00
IUUC-Nle-069479	Nomascus leucogenys	83.12	0.00e+00	1538.00
IUUC-Opr-070717	Ochotona princeps	73.88	0.00e+00	1136.00
IUUC-Ont-071702	Oreochromis niloticus	47.49	0.00e+00	868.00
IUUC-Oan-073639	Ornithorhynchus anatinus	66.38	0.00e+00	1196.00
IUUC-Ocu-074521	Oryctolagus cuniculus	82.15	0.00e+00	1590.00
IUUC-Ola-086351	Oryzias latipes	46.18	0.00e+00	818.00
IUUC-Oga-088539	Otolemur garnettii	81.66	0.00e+00	1549.00
IUUC-Oar-090186	Ovis aries	80.98	0.00e+00	1499.00
IUUC-Ptr-090575	Pan troglodytes	83.12	0.00e+00	1535.00
IUUC-Pan-092371	Papio anubis	86.54	0.00e+00	1590.00
IUUC-Psi-093072	Pelodiscus sinensis	63.43	0.00e+00	1254.00
IUUC-Pma-094345	Petromyzon marinus	42.70	9.00e-93	333.00
IUUC-Pfo-096401	Poecilia formosa	52.70	0.00e+00	682.00
IUUC-Pab-097623	Pongo abelii	84.29	0.00e+00	1562.00
IUUC-Pca-100993	Procavia capensis	75.40	0.00e+00	1261.00
IUUC-Pva-102227	Pteropus vampyrus	76.90	0.00e+00	1421.00
IUUC-Rno-105198	Rattus norvegicus	77.90	0.00e+00	1585.00
IUUC-Sha-107622	Sarcophilus harrisii	71.91	0.00e+00	1415.00
IUUC-Sar-113625	Sorex araneus	68.71	0.00e+00	726.00
IUUC-Tgu-117486	Taeniopygia guttata	59.35	0.00e+00	1118.00
IUUC-Tru-118445	Takifugu rubripes	45.88	0.00e+00	821.00
IUUC-Tsy-119512	Tarsius syrichta	82.34	0.00e+00	1491.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.78	0.00e+00	833.00
IUUC-Tbe-127644	Tupaia belangeri	74.24	0.00e+00	1373.00
IUUC-Ttr-128989	Tursiops truncatus	78.15	0.00e+00	1522.00
IUUC-Vpa-130587	Vicugna pacos	78.49	0.00e+00	1227.00
IUUC-Xtr-132127	Xenopus tropicalis	53.04	0.00e+00	1026.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence