iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050502

Ensembl Protein ID

ENSLACP00000011416.1

UniProt Accession

H3AP45; H3AP45_LATCH

Genbank Protein ID

ENSLACP00000011416

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01042831

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010044.1	ENSLACT00000011502.1	ENSLACP00000011416.1
ENSLACG00000010044.1	ENSLACT00000011503.1	ENSLACP00000011417.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.00e-67	221.3	590	640

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           v+ +ydy+aqnddeL + kG ++ v+  ++ d +W+kg  el+g  GlfP+n+v+
   Q: 590  VIGMYDYMAQNDDELAFAKGQIINVL--NKDDPDWWKG--ELNGLTGLFPSNYVK 640
           6779**********************..8889******..9*************8 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

QELREIHNKQ QLQKQKEMEA EKQKEQEKKM AELEKQKEEA QRIKQWKRMH ALVNGECGLG 60
LFSPRRAQEQ EKQWQEQVQK EEEEERRWKM QDEEKQKKED ATKMKEPEEK SKQEMQDKLN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAATTAA GGGAAATTCA TAATAAACAG CAGCTACAGA AACAAAAGGA AATGGAAGCT 60
GAGAAGCAGA AAGAGCAGGA GAAGAAGATG GCAGAGCTGG AGAAGCAGAA AGAAGAAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00168--C2
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001218	Ailuropoda melanoleuca	75.42	0.00e+00	1742.00
IUUC-Apl-003335	Anas platyrhynchos	75.51	0.00e+00	1713.00
IUUC-Aca-005130	Anolis carolinensis	73.90	0.00e+00	1669.00
IUUC-Ago-007935	Ashbya gossypii	34.07	3.00e-14	73.60
IUUC-Ani-009403	Aspergillus nidulans	41.53	5.00e-15	72.40
IUUC-Ame-011878	Astyanax mexicanus	73.47	0.00e+00	1553.00
IUUC-Bta-012863	Bos taurus	74.58	0.00e+00	1692.00
IUUC-Cja-019012	Callithrix jacchus	75.08	0.00e+00	1687.00
IUUC-Cfa-020272	Canis familiaris	75.42	0.00e+00	1738.00
IUUC-Cpo-021352	Cavia porcellus	70.59	0.00e+00	1605.00
IUUC-Dre-028623	Danio rerio	72.07	0.00e+00	1553.00
IUUC-Dno-030044	Dasypus novemcinctus	75.30	0.00e+00	1729.00
IUUC-Dor-030272	Dipodomys ordii	68.97	0.00e+00	1553.00
IUUC-Dme-032099	Drosophila melanogaster	37.05	3.00e-51	197.00
IUUC-Ete-032927	Echinops telfairi	79.58	0.00e+00	850.00
IUUC-Eca-033469	Equus caballus	75.34	0.00e+00	1707.00
IUUC-Eeu-034977	Erinaceus europaeus	67.99	0.00e+00	668.00
IUUC-Fca-036419	Felis catus	74.77	0.00e+00	1722.00
IUUC-Fal-037236	Ficedula albicollis	74.51	0.00e+00	1727.00
IUUC-Gmo-039632	Gadus morhua	68.36	0.00e+00	1345.00
IUUC-Gga-040835	Gallus gallus	71.35	0.00e+00	1660.00
IUUC-Gac-041948	Gasterosteus aculeatus	72.55	0.00e+00	1480.00
IUUC-Hsa-045699	Homo sapiens	75.51	0.00e+00	1738.00
IUUC-Hvu-047839	Hordeum vulgare	33.33	3.00e-08	50.80
IUUC-Itr-048773	Ictidomys tridecemlineatus	71.17	0.00e+00	1628.00
IUUC-Loc-052613	Lepisosteus oculatus	74.50	0.00e+00	1580.00
IUUC-Laf-053608	Loxodonta africana	74.75	0.00e+00	1723.00
IUUC-Mcc-055720	Macaca mulatta	75.08	0.00e+00	1708.00
IUUC-Meu-056445	Macropus eugenii	74.61	0.00e+00	1507.00
IUUC-Mmr-061258	Microcebus murinus	74.92	0.00e+00	1693.00
IUUC-Mdo-062019	Monodelphis domestica	78.70	0.00e+00	1633.00
IUUC-Mmu-063885	Mus musculus	73.84	0.00e+00	1718.00
IUUC-Opr-070441	Ochotona princeps	72.37	0.00e+00	1609.00
IUUC-Ont-071752	Oreochromis niloticus	71.88	0.00e+00	1456.00
IUUC-Oan-073390	Ornithorhynchus anatinus	71.44	0.00e+00	1584.00
IUUC-Obr-076390	Oryza brachyantha	35.90	6.00e-09	55.10
IUUC-Oga-088602	Otolemur garnettii	74.49	0.00e+00	1706.00
IUUC-Oar-090195	Ovis aries	74.69	0.00e+00	1706.00
IUUC-Ptr-091363	Pan troglodytes	75.51	0.00e+00	1737.00
IUUC-Pan-092385	Papio anubis	75.25	0.00e+00	1715.00
IUUC-Pfo-097486	Poecilia formosa	68.00	0.00e+00	1525.00
IUUC-Pca-100270	Procavia capensis	63.54	0.00e+00	895.00
IUUC-Pva-102335	Pteropus vampyrus	74.34	0.00e+00	1708.00
IUUC-Rno-106122	Rattus norvegicus	73.31	0.00e+00	1698.00
IUUC-Sha-106851	Sarcophilus harrisii	73.06	0.00e+00	1670.00
IUUC-Tgu-117028	Taeniopygia guttata	74.77	0.00e+00	1737.00
IUUC-Tru-117789	Takifugu rubripes	72.23	0.00e+00	1511.00
IUUC-Tsy-119039	Tarsius syrichta	78.63	0.00e+00	1171.00
IUUC-Tni-119952	Tetraodon nigroviridis	67.36	0.00e+00	1513.00
IUUC-Tbe-127754	Tupaia belangeri	68.72	0.00e+00	746.00
IUUC-Ttr-129178	Tursiops truncatus	78.38	0.00e+00	1678.00
IUUC-Vpa-130687	Vicugna pacos	69.40	0.00e+00	740.00
IUUC-Xtr-132905	Xenopus tropicalis	74.01	0.00e+00	1679.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence