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Tag Content
UUCD2 ID IUUC-Cfa-020408
UUCD1 version UUC-CaF-00988
Ensembl Protein ID ENSCAFP00000002344.4
UniProt Accession E2RP15; E2RP15_CANLF
Genbank Protein ID ENSCAFP00000002344
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAEX03008323
Gene Name USP49
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000001609.4 ENSCAFT00000002525.4 ENSCAFP00000002344.4
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.30e-98 329.8 247 650
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp............................................... 42
           tGl+NlgNtCYmNS+LQ+Ls+++++re++l  +++++++  p                                               
   Q: 247  TGLRNLGNTCYMNSILQVLSHLQKFRECFLYLDPSQTQQLFPkapngkaplsgrpaasaaelsarsggaeacereglcfnggasisrsl 335
           7******************************8888888777777789999999999999999999999999999999999999999999 PP
   S: 43   ........kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedk 123
                   ++++ +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ ll+++++el         e+e++++
   Q: 336  eliqnkepSSKHISLCHELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQEL---------ESEGTTR 415
           9999999888899************************************************************.........6688888 PP
   S: 124  selsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..........slqdcLesftkeeeleg 202
           + l   +++k +k+  ++++++F+gql sq++c +c+ +s++ epf+dlsl++p++ ++ ++           l+++L++ft++e leg
   Q: 416  RILIPFSQRKLTKQVLKVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEKgfvplnqtecLLTEMLAKFTETEALEG 504
           999999***************************************************998879*************************9 PP
   S: 203  enkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kkkY 278
           +  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c+++  ++ +  +  Y
   Q: 505  RI-YACDQCNSKRRksnpkplvlseARKQLMIYRLPQVLRLHLKRFRWSGR-NHREKIGVHVVFDQVLTMEPYCCRDMLSSLDkeTFAY 591
           65.*******9999999*******************************997.8889********************876654433999* PP
   S: 279  eLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk ++++ eev++   ++aY+lfY++r
   Q: 592  DLSAVVMHHGkGFGSGHYTAYCYNTEGGfWVHCNDSKLNVCSVEEVCK---TQAYILFYTQR 650
           ************************9999********************...********985 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MDRCKHVGRL RLAQDHSILN PQKWCCRECA TTESVWACLK CSHVACGRYI EDHALKHFEE 60
TGHPLAMEVR DLYVFCYLCK DYVLNDNPEG DLKLLRSSLL AVRGQKQDPP LRRGRTLRSM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020408|DUB,USP|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGATAGAT GCAAACATGT CGGGCGGTTG CGGCTCGCCC AGGACCACTC CATCCTGAAC 60
CCGCAGAAGT GGTGCTGCAG GGAGTGCGCC ACCACCGAGT CCGTGTGGGC TTGTCTCAAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020408|DUB,USP|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0000398--P:mRNA splicing, via spliceosome
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG cfa:474899
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002395 Ailuropoda melanoleuca 97.89 0.00e+00 865.00
IUUC-Apl-003658 Anas platyrhynchos 78.74 0.00e+00 1034.00
IUUC-Aca-005278 Anolis carolinensis 79.19 0.00e+00 1058.00
IUUC-Bta-012911 Bos taurus 94.13 0.00e+00 1169.00
IUUC-Cja-019171 Callithrix jacchus 90.68 0.00e+00 1189.00
IUUC-Cpo-022233 Cavia porcellus 84.80 0.00e+00 1062.00
IUUC-Csa-024272 Chlorocebus sabaeus 89.77 0.00e+00 941.00
IUUC-Cho-025051 Choloepus hoffmanni 90.29 0.00e+00 649.00
IUUC-Dno-029856 Dasypus novemcinctus 89.96 0.00e+00 1162.00
IUUC-Ete-032761 Echinops telfairi 74.72 0.00e+00 827.00
IUUC-Eca-033851 Equus caballus 85.74 0.00e+00 1026.00
IUUC-Fca-035919 Felis catus 97.24 0.00e+00 804.00
IUUC-Fal-037290 Ficedula albicollis 75.95 0.00e+00 919.00
IUUC-Gmo-039249 Gadus morhua 77.67 5.00e-146 511.00
IUUC-Ggo-044979 Gorilla gorilla 91.12 0.00e+00 1172.00
IUUC-Hsa-046743 Homo sapiens 91.27 0.00e+00 1174.00
IUUC-Itr-048251 Ictidomys tridecemlineatus 92.54 0.00e+00 1202.00
IUUC-Lch-050294 Latimeria chalumnae 75.43 0.00e+00 937.00
IUUC-Loc-051961 Lepisosteus oculatus 77.86 0.00e+00 645.00
IUUC-Laf-053819 Loxodonta africana 94.38 0.00e+00 842.00
IUUC-Mcc-055048 Macaca mulatta 91.41 0.00e+00 1172.00
IUUC-Meu-055971 Macropus eugenii 66.59 5.00e-141 494.00
IUUC-Mmr-061253 Microcebus murinus 87.22 2.00e-156 545.00
IUUC-Mdo-062073 Monodelphis domestica 81.03 0.00e+00 1075.00
IUUC-Mmu-064095 Mus musculus 89.56 0.00e+00 1149.00
IUUC-Mpu-066318 Mustela putorius furo 97.93 0.00e+00 883.00
IUUC-Mlu-067090 Myotis lucifugus 91.78 0.00e+00 1154.00
IUUC-Nle-069486 Nomascus leucogenys 91.56 0.00e+00 1178.00
IUUC-Opr-070563 Ochotona princeps 88.63 0.00e+00 1150.00
IUUC-Oan-073245 Ornithorhynchus anatinus 89.68 2.00e-180 625.00
IUUC-Ocu-074851 Oryctolagus cuniculus 90.24 0.00e+00 938.00
IUUC-Ola-086413 Oryzias latipes 61.75 2.00e-173 602.00
IUUC-Oga-088862 Otolemur garnettii 89.37 0.00e+00 1157.00
IUUC-Oar-089462 Ovis aries 91.53 0.00e+00 815.00
IUUC-Ptr-091525 Pan troglodytes 90.73 0.00e+00 1048.00
IUUC-Pan-092363 Papio anubis 91.54 0.00e+00 1125.00
IUUC-Psi-093353 Pelodiscus sinensis 80.20 0.00e+00 1048.00
IUUC-Pma-094155 Petromyzon marinus 60.27 1.00e-81 296.00
IUUC-Pfo-096413 Poecilia formosa 60.26 0.00e+00 740.00
IUUC-Pab-098592 Pongo abelii 89.77 0.00e+00 941.00
IUUC-Pca-100449 Procavia capensis 89.28 0.00e+00 1147.00
IUUC-Pva-102868 Pteropus vampyrus 92.66 0.00e+00 1181.00
IUUC-Rno-105190 Rattus norvegicus 87.72 0.00e+00 1140.00
IUUC-Sha-107337 Sarcophilus harrisii 80.97 0.00e+00 1058.00
IUUC-Sar-113561 Sorex araneus 95.78 2.00e-94 339.00
IUUC-Ssc-115735 Sus scrofa 95.89 0.00e+00 1182.00
IUUC-Tgu-117025 Taeniopygia guttata 71.09 0.00e+00 846.00
IUUC-Tru-117585 Takifugu rubripes 59.10 0.00e+00 723.00
IUUC-Tsy-118814 Tarsius syrichta 89.96 0.00e+00 1152.00
IUUC-Vpa-130263 Vicugna pacos 96.66 0.00e+00 791.00
IUUC-Xtr-132090 Xenopus tropicalis 70.77 0.00e+00 912.00
Created Date 25-Jun-2017

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